≥99% for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
Store at -20°C Ships Ice chest + Ice pads Check lot-specific COA for exact specifications.
SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
Glycolithocholic acid 3-sulfate (SLCG) is a cholic acid derivative and a metabolite of glycolithocholic acid. Glycolithocholic acid 3-sulfate inhibits replication of HIV-1 in vitro. Glycolithocholic acid 3-sulfate can be used for the research of HIV infection and gallbladder disease
In Vitro
Glycolithocholic acid 3-sulfate (100 μg/mL) protects MT-4 cells against HIV-1-induced cytopathogenicity. Glycolithocholic acid 3-sulfate (200 μg/mL) shows no toxicity for host cells. Glycolithocholic acid 3-sulfate inhibits HIV-1 antigen expression in HIV-1-infected CEM cells. MCE has not independently confirmed the accuracy of these methods. They are for reference only.
In Vivo
Glycolithocholic acid 3-sulfate (24 μmoL /100 g; i.v., once) induces intrahepatic cholestasis and increases biliary cholesterol secretion in male Wistar rats with bile fistula. MCE has not independently confirmed the accuracy of these methods. They are for reference only. Animal Model: Male Wistar rats with bile fistulaDosage: 24 μmoL/100 g Administration: Intravenous injection; 24 μmoL/100 g Result: Induced intrahepatic cholestasis and increased biliary cholesterol secretion.
Form:Solid
IC50& Target:Microbial Metabolite
| Isomeric SMILES | C[C@H](CCC(=O)NCC(=O)O)[C@H]1CC[C@@H]2[C@@]1(CC[C@H]3[C@H]2CC[C@H]4[C@@]3(CC[C@H](C4)OS(=O)(=O)O)C)C |
|---|---|
| PubChem CID | 72222 |
| Molecular Weight | 513.69 |
Comprehensive hazard, handling, storage, and regulatory compliance document.
Download SDS →Lot-specific quality data. Enter your lot number to retrieve the exact COA.
Look up COA →Full quality attributes and acceptance criteria for this grade.
View spec sheet →| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
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| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
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| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
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| Molecular Weight | 513.700 g/mol |
|---|---|
| XLogP3 | 5.200 |
| Hydrogen Bond Donor Count | 3 |
| Hydrogen Bond Acceptor Count | 7 |
| Rotatable Bond Count | 8 |
| Exact Mass | 513.276 Da |
| Monoisotopic Mass | 513.276 Da |
| Topological Polar Surface Area | 138.000 Ų |
| Heavy Atom Count | 35 |
| Formal Charge | 0 |
| Complexity | 917.000 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 9 |
| Undefined Atom Stereocenter Count | 0 |
| Defined Bond Stereocenter Count | 0 |
| Undefined Bond Stereocenter Count | 0 |
| The total count of all stereochemical bonds | 0 |
| Covalently-Bonded Unit Count | 1 |
