Guanosine 5'-triphosphate trisodium salt hydrate - 10mM in Water , CAS No.36051-31-7

CAS: 36051-31-7 Cat. No.: G423621 Molecular Weight: 589.13 Beilstein Registry Number: 3585677 EC Number: 252-847-2 PubChem CID: 135445727

GRADE & PURITY 10mM in Water

Synonyms

36051-31-7|Guanosine 5'-triphosphate trisodium salt|GTP Trisodium salt|5'-GTP trisodium salt|Guanosine-5'-triphosphate sodium salt|AKOS025290404|guanosine 5'-tri-phosphate sodium salt|Guanosine 5-triphosphate trisodium salt|AC-32416|E78651|Guanosine 5'-tr

Storage

Store at -80°C

Shipped In

Dry ice packs + Cold packs

Overview

Guanosine 5′-triphosphate (GTP), a purine trinucleotide, is a substrate for RNA polymerases and a wide range of GTPase including G-protein coupled receptor (GPCR) GTPases and cell signaling and cycling associated guanine nucleotide exhange factors (GEF).

Specifications

Synonyms

36051-31-7 | Guanosine 5'-triphosphate trisodium salt | GTP Trisodium salt | 5'-GTP trisodium salt | Guanosine-5'-triphosphate sodium salt | AKOS025290404 | guanosine 5'-tri-phosphate sodium salt | Guanosine 5-triphosphate trisodium salt | AC-32416 | E78651 | Guanosine 5'-tr

Specifications & Purity

10mM in Water

Biochemical and Physiological Mechanisms

Nucleoside triphosphate. Functions as a carrier of phosphates and pyrophosphates involved in channeling chemical energy into specific biosynthetic pathways. Activates signal transducing G proteins。

Storage

Store at -80°C

Shipped In

Dry ice packs + Cold packs

This product requires cold chain shipping. Ground and other economy services are not available.

Names and Identifiers

• Canonical Smiles: C1=NC2=C(N1C3C(C(C(O3)COP(=O)(O)OP(=O)([O-])OP(=O)([O-])[O-])O)O)N=C(NC2=O)N.[Na+].[Na+].[Na+]
• IUPAC Name: trisodium;[[[(2R,3S,4R,5R)-5-(2-amino-6-oxo-1H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-oxidophosphoryl] phosphate
• InChIKey: KZRMTEVIDYXWQW-CYCLDIHTSA-K
• INCHI: 1S/C10H16N5O14P3.3Na/c11-10-13-7-4(8(18)14-10)12-2-15(7)9-6(17)5(16)3(27-9)1-26-31(22,23)29-32(24,25)28-30(19,20)21;;;/h2-3,5-6,9,16-17H,1H2,(H,22,23)(H,24,25)(H2,19,20,21)(H3,11,13,14,18);;;/q;3*+1/p-3/t3-,5-,6-,9-;;;/m1.../s1
• Isomeric SMILES: C1=NC2=C(N1[C@H]3[C@@H]([C@@H]([C@H](O3)COP(=O)(O)OP(=O)([O-])OP(=O)([O-])[O-])O)O)N=C(NC2=O)N.[Na+].[Na+].[Na+]
• WGK Germany: 3
• PubChem CID: 135445727
• Molecular Weight: 589.13
• Beilstein: 3585677

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Nucleosides, nucleotides, and analogues
    • Class Purine nucleotides
      • Subclass Purine ribonucleotides

• Kingdom: Organic compounds
• Superclass: Nucleosides, nucleotides, and analogues
• Class: Purine nucleotides
• Subclass: Purine ribonucleotides
• Intermediate Tree Nodes: Not available
• Direct Parent: Purine ribonucleoside triphosphates
• Alternative Parents: Purine ribonucleoside monophosphates Pentose phosphates Glycosylamines 6-oxopurines Monosaccharide phosphates Hypoxanthines Pyrimidones Aminopyrimidines and derivatives Alkyl phosphates N-substituted imidazoles Vinylogous amides Oxolanes Heteroaromatic compounds Secondary alcohols 1,2-diols Oxacyclic compounds Azacyclic compounds Primary amines Organic sodium salts Organic zwitterions Organic oxides Hydrocarbon derivatives
• Molecular Framework: Aromatic heteropolycyclic compounds
• Substituents: Purine ribonucleoside triphosphate - Purine ribonucleoside monophosphate - Pentose phosphate - Pentose-5-phosphate - Glycosyl compound - N-glycosyl compound - 6-oxopurine - Hypoxanthine - Monosaccharide phosphate - Pentose monosaccharide - Imidazopyrimidine - Purine - Aminopyrimidine - Pyrimidone - Monosaccharide - N-substituted imidazole - Organic phosphoric acid derivative - Phosphoric acid ester - Pyrimidine - Alkyl phosphate - Vinylogous amide - Azole - Heteroaromatic compound - Imidazole - Oxolane - Secondary alcohol - 1,2-diol - Organoheterocyclic compound - Organic alkali metal salt - Oxacycle - Azacycle - Organic sodium salt - Primary amine - Organic zwitterion - Organic oxygen compound - Hydrocarbon derivative - Organic oxide - Organic salt - Amine - Organooxygen compound - Organic nitrogen compound - Alcohol - Organonitrogen compound - Aromatic heteropolycyclic compound
• Description: This compound belongs to the class of organic compounds known as purine ribonucleoside triphosphates. These are purine ribobucleotides with a triphosphate group linked to the ribose moiety.
• External Descriptors: Not available

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

Chemical and Physical Properties

• Molecular Weight: 589.130 g/mol
• Hydrogen Bond Donor Count: 5
• Hydrogen Bond Acceptor Count: 16
• Rotatable Bond Count: 7
• Exact Mass: 588.936 Da
• Monoisotopic Mass: 588.936 Da
• Topological Polar Surface Area: 303.000 Ų
• Heavy Atom Count: 35
• Formal Charge: 0
• Complexity: 907.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 4
• Undefined Atom Stereocenter Count: 0
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 4

XLogP3

References

1. Liu Xianglan, Hu Jiaming, Wu Jiarui, Tian Yiru, Wang Jinbo, Wu Chunyan, Chen Qingfeng, Krall Leonard, He Yanping, Lu Qun.  (2025)  Identification of Co-29, a 5-cyano-2-thiacetyl aromatic pyrimidinone, as a potential inhibitor targeting the RdRp of norovirus.  Virology Journal,  22  (1): (1-14).  [PMID:40186285] [10.1186/s12985-025-02687-w]