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· · COA & SDS available for every product · Same-day shipping on in-stock items Hemicholinium-3 - Moligand™, ≥95% , CHT, CAS No.312-45-8, CHT
GRADE & PURITY Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥95% Synonyms
NSC 527583 | Prestwick_566 | SR-01000075620-1 | LP00578 | 2,2'-(1,1'-Biphenyl)-4,4'-diylbis(2-hydroxy-4,4-dimethyl-morpholinium) dibromide | GTPL4493 | Morpholinium, 2,2'-(1,1'-biphenyl)-4,4'-diylbis(2-hydroxy-4,4-dimethyl-, bromide (1:2) | H-108 | 2,2'-(
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Why this grade Moligand™, ≥95% Moligand™ for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
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Storage & shipping Store at 2-8°C Ships Wet ice Check lot-specific COA for exact specifications.
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Quality documents SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
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Literature proof Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
Overview A potent and selective choline uptake blocker.
Specifications Synonyms
NSC 527583 | Prestwick_566 | SR-01000075620-1 | LP00578 | 2, 2'-(1, 1'-Biphenyl)-4, 4'-diylbis(2-hydroxy-4, 4-dimethyl-morpholinium) dibromide | GTPL4493 | Morpholinium, 2, 2'-(1, 1'-biphenyl)-4, 4'-diylbis(2-hydroxy-4, 4-dimethyl-, bromide (1:2) | H-108 | 2, 2'-(
Specifications & Purity
Moligand™, ≥95%
Biochemical and Physiological Mechanisms
The role of acetylcholine-3 in blocking neuronal choline uptake, and thus in inhibiting the synthesis of choline in the brain, may play a role in blocking neuronal choline uptake, which inhibits the production of acetylcholine in the brain
Shipped In
Wet ice
This product requires cold chain shipping. Ground and other economy services are not available.
Names and Identifiers Pubchem Sid 488180974 Pubchem Sid Url https://pubchem.ncbi.nlm.nih.gov/substance/488180974 Canonical Smiles C[N+]1(CCOC(C1)(C2=CC=C(C=C2)C3=CC=C(C=C3)C4(C[N+](CCO4)(C)C)O)O)C.[Br-].[Br-] IUPAC Name 2-[4-[4-(2-hydroxy-4,4-dimethylmorpholin-4-ium-2-yl)phenyl]phenyl]-4,4-dimethylmorpholin-4-ium-2-ol;dibromide InChIKey OPYKHUMNFAMIBL-UHFFFAOYSA-L INCHI 1S/C24H34N2O4.2BrH/c1-25(2)13-15-29-23(27,17-25)21-9-5-19(6-10-21)20-7-11-22(12-8-20)24(28)18-26(3,4)14-16-30-24;;/h5-12,27-28H,13-18H2,1-4H3;2*1H/q+2;;/p-2 Isomeric SMILES C[N+]1(CCOC(C1)(C2=CC=C(C=C2)C3=CC=C(C=C3)C4(C[N+](CCO4)(C)C)O)O)C.[Br-].[Br-] WGK Germany 3 RTECS QF2450000 Alternate CAS 312-45-8 MeSH Entry Terms Hemicholinium;Hemicholinium 3 Molecular Weight 574.35 Reaxy-Rn 5704458 Reaxys-RN_link_address https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=5704458&ln=
Documentation 📋 Safety Data Sheet (SDS) Comprehensive hazard, handling, storage, and regulatory compliance document.
Download SDS → ✅ Certificate of Analysis (COA) Lot-specific quality data. Enter your lot number to retrieve the exact COA.
Look up COA → 📊 Datasheet Quick-reference summary of product specifications and applications.
View datasheet → 🔬 Specification Sheet Full quality attributes and acceptance criteria for this grade.
View spec sheet →
Advanced Data Taxonomic Classification Kingdom Organic compounds Superclass Organoheterocyclic compounds Class Oxazinanes Subclass Morpholines Intermediate Tree Nodes Not available Direct Parent Phenylmorpholines Alternative Parents Biphenyls and derivatives Aralkylamines Tetraalkylammonium salts Hemiacetals Oxacyclic compounds Azacyclic compounds Organopnictogen compounds Organic zwitterions Organic bromide salts Hydrocarbon derivatives Molecular Framework Aromatic heteromonocyclic compounds Substituents Biphenyl - Phenylmorpholine - Aralkylamine - Monocyclic benzene moiety - Benzenoid - Tetraalkylammonium salt - Quaternary ammonium salt - Hemiacetal - Oxacycle - Azacycle - Organic zwitterion - Amine - Hydrocarbon derivative - Organooxygen compound - Organonitrogen compound - Organopnictogen compound - Organic oxygen compound - Organic nitrogen compound - Organic salt - Organic bromide salt - Aromatic heteromonocyclic compound Description This compound belongs to the class of organic compounds known as phenylmorpholines. These are aromatic compounds containing a morpholine ring and a benzene ring linked to each other through a CC or a CN bond. External Descriptors Not available Data sources 1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.
3D Structure Associated Targets(Human) Associated Targets(non-human) Mechanisms of Action Certificates（CoA,COO,BSE/TSE and Analysis Chart) Chemical and Physical Properties Solubility Soluble in ethanol: 1.3 mg/mL: water: 10 mg/mL Sensitivity moisture sensitive Melt Point(°C) 180° C Molecular Weight 574.300 g/mol XLogP3 Hydrogen Bond Donor Count 2 Hydrogen Bond Acceptor Count 6 Rotatable Bond Count 3 Exact Mass 574.086 Da Monoisotopic Mass 572.089 Da Topological Polar Surface Area 58.900 Ų Heavy Atom Count 32 Formal Charge 0 Complexity 544.000 Isotope Atom Count 0 Defined Atom Stereocenter Count 0 Undefined Atom Stereocenter Count 2 Defined Bond Stereocenter Count 0 Undefined Bond Stereocenter Count 0 The total count of all stereochemical bonds 0 Covalently-Bonded Unit Count 3
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