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· · COA & SDS available for every product · Same-day shipping on in-stock items Isosakuranetin - Moligand™, ≥98% , Channel blocker of TRPM3, CAS No.480-43-3, Channel blocker of TRPM3
GRADE & PURITY Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98% Synonyms
BRD-K19341706-001-01-7 | CCG-208396 | 5'-METHYL-2'-HYDROXYACETOPHENONE | SR-05000002273-2 | EINECS 207-551-8 | 5,7-dihydroxy-4''-methoxyflavanone | 5,7-Dihydroxy-4'-methoxyflavanone | (S)-2,3-dihydro-5,7-dihydroxy-2-(4-methoxyphenyl)-4H-1-benzopyran-4-one
Storage
Protected from light,Store at -20°C
Shipped In
Ice chest + Ice pads
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Why this grade Moligand™, ≥98% Moligand™ for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
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Storage & shipping Protected from light,Store at -20°C Ships Ice chest + Ice pads Check lot-specific COA for exact specifications.
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Quality documents SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
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Literature proof Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
Overview Information
Isosakuranetin (4'-Methylnaringenin), an O-methylated flavonoid, is the 4'-methoxy derivative of naringenin, a flavanone found inCitrusspecies.
Specifications Synonyms
BRD-K19341706-001-01-7 | CCG-208396 | 5'-METHYL-2'-HYDROXYACETOPHENONE | SR-05000002273-2 | EINECS 207-551-8 | 5, 7-dihydroxy-4''-methoxyflavanone | 5, 7-Dihydroxy-4'-methoxyflavanone | (S)-2, 3-dihydro-5, 7-dihydroxy-2-(4-methoxyphenyl)-4H-1-benzopyran-4-one
Specifications & Purity
Moligand™, ≥98%
Biochemical and Physiological Mechanisms
Isosakuranetin (4'-Methylnaringenin), an O-methylated flavonoid, is the 4'-methoxy derivative of naringenin, a flavanone found in Citrus species.
Storage
Protected from light, Store at -20°C
Shipped In
Ice chest + Ice pads
This product requires cold chain shipping. Ground and other economy services are not available.
Action Type
CHANNEL BLOCKER
Mechanism of action
Channel blocker of TRPM3
Product Properties ALogP 2.599 hba_count 3 HBD Count 2 Rotatable Bond 2
Names and Identifiers Pubchem Sid 488188316 Pubchem Sid Url https://pubchem.ncbi.nlm.nih.gov/substance/488188316 Canonical Smiles COC1=CC=C(C=C1)C2CC(=O)C3=C(C=C(C=C3O2)O)O IUPAC Name (2S)-5,7-dihydroxy-2-(4-methoxyphenyl)-2,3-dihydrochromen-4-one InChIKey HMUJXQRRKBLVOO-AWEZNQCLSA-N INCHI 1S/C16H14O5/c1-20-11-4-2-9(3-5-11)14-8-13(19)16-12(18)6-10(17)7-15(16)21-14/h2-7,14,17-18H,8H2,1H3/t14-/m0/s1 Isomeric SMILES COC1=CC=C(C=C1)[C@@H]2CC(=O)C3=C(C=C(C=C3O2)O)O Alternate CAS 480-43-3 MeSH Entry Terms isosakuranetin Molecular Weight 286.28 Reaxy-Rn 91628 Reaxys-RN_link_address https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=91628&ln=
Documentation 📋 Safety Data Sheet (SDS) Comprehensive hazard, handling, storage, and regulatory compliance document.
Download SDS → ✅ Certificate of Analysis (COA) Lot-specific quality data. Enter your lot number to retrieve the exact COA.
Look up COA → 📊 Datasheet Quick-reference summary of product specifications and applications.
View datasheet → 🔬 Specification Sheet Full quality attributes and acceptance criteria for this grade.
View spec sheet →
Advanced Data Taxonomic Classification Kingdom Organic compounds Superclass Phenylpropanoids and polyketides Class Flavonoids Subclass O-methylated flavonoids Intermediate Tree Nodes Not available Direct Parent 4'-O-methylated flavonoids Alternative Parents Flavanones 7-hydroxyflavonoids 5-hydroxyflavonoids Chromones Phenoxy compounds Methoxybenzenes Aryl alkyl ketones Anisoles Alkyl aryl ethers 1-hydroxy-4-unsubstituted benzenoids 1-hydroxy-2-unsubstituted benzenoids Vinylogous acids Oxacyclic compounds Organic oxides Hydrocarbon derivatives Molecular Framework Aromatic heteropolycyclic compounds Substituents 4p-methoxyflavonoid-skeleton - 5-hydroxyflavonoid - 7-hydroxyflavonoid - Flavanone - Hydroxyflavonoid - Flavan - Chromone - Benzopyran - Chromane - 1-benzopyran - Phenoxy compound - Methoxybenzene - Anisole - Phenol ether - Aryl ketone - Aryl alkyl ketone - Alkyl aryl ether - 1-hydroxy-4-unsubstituted benzenoid - 1-hydroxy-2-unsubstituted benzenoid - Monocyclic benzene moiety - Benzenoid - Vinylogous acid - Ketone - Oxacycle - Organoheterocyclic compound - Ether - Organic oxide - Organic oxygen compound - Organooxygen compound - Hydrocarbon derivative - Aromatic heteropolycyclic compound Description This compound belongs to the class of organic compounds known as 4'-o-methylated flavonoids. These are flavonoids with methoxy groups attached to the C4' atom of the flavonoid backbone. External Descriptors Flavanones Data sources 1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.
3D Structure Associated Targets(Human) Associated Targets(non-human) Mechanisms of Action Certificates（CoA,COO,BSE/TSE and Analysis Chart) Chemical and Physical Properties Solubility Solubility (25°C) In vitro DMSO: 57 mg/mL (199.1 mM); Sensitivity light & moisture & heat sensitive DMSO(mg / mL) Max Solubility 57 DMSO(mM) Max Solubility 199.106215690855 Molecular Weight 286.280 g/mol XLogP3 2.700 Hydrogen Bond Donor Count 2 Hydrogen Bond Acceptor Count 5 Rotatable Bond Count 2 Exact Mass 286.084 Da Monoisotopic Mass 286.084 Da Topological Polar Surface Area 76.000 Ų Heavy Atom Count 21 Formal Charge 0 Complexity 377.000 Isotope Atom Count 0 Defined Atom Stereocenter Count 1 Undefined Atom Stereocenter Count 0 Defined Bond Stereocenter Count 0 Undefined Bond Stereocenter Count 0 The total count of all stereochemical bonds 0 Covalently-Bonded Unit Count 1
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