Determine the necessary mass, volume, or concentration for preparing a solution.
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Moligand™, ≥98% Moligand™ for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
Store at -20°C,Argon charged Ships Ice chest + Ice pads Check lot-specific COA for exact specifications.
SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
Cited in 17 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
Carnosine is an antioxidant. Inhibits soluble guanylyl cyclase (sGC) by interacting with the heme iron to form a chelate complex.
An antioxidant soluble guanylyl cyclase inhibitor.
| Canonical Smiles | C1=C(NC=N1)CC(C(=O)O)NC(=O)CCN |
|---|---|
| IUPAC Name | (2S)-2-(3-aminopropanoylamino)-3-(1H-imidazol-5-yl)propanoic acid |
| InChIKey | CQOVPNPJLQNMDC-ZETCQYMHSA-N |
| INCHI | 1S/C9H14N4O3/c10-2-1-8(14)13-7(9(15)16)3-6-4-11-5-12-6/h4-5,7H,1-3,10H2,(H,11,12)(H,13,14)(H,15,16)/t7-/m0/s1 |
| Isomeric SMILES | C1=C(NC=N1)C[C@@H](C(=O)O)NC(=O)CCN |
| WGK Germany | 2 |
| RTECS | MS3080000 |
| Alternate CAS | 305-84-0,1370422-07-3 |
| MeSH Entry Terms | beta Alanylhistidine;beta-Alanylhistidine;Carnosine;Carnosine Hydrochloride;Carnosine, (D-His)-Isomer;Hydrochloride, Carnosine;L Carnosine;L-Carnosine |
| Molecular Weight | 226.23 |
| Beilstein | 87671 |
| Reaxy-Rn | 535203 |
| Reaxys-RN_link_address | https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=535203&ln= |
Comprehensive hazard, handling, storage, and regulatory compliance document.
Download SDS →Lot-specific quality data. Enter your lot number to retrieve the exact COA.
Look up COA →Full quality attributes and acceptance criteria for this grade.
View spec sheet →Taxonomy Tree
| Kingdom | Organic compounds |
|---|---|
| Superclass | Organic acids and derivatives |
| Class | Peptidomimetics |
| Subclass | Hybrid peptides |
| Intermediate Tree Nodes | Not available |
| Direct Parent | Hybrid peptides |
| Alternative Parents | Histidine and derivatives N-acyl-L-alpha-amino acids Beta amino acids and derivatives Imidazolyl carboxylic acids and derivatives Heteroaromatic compounds Secondary carboxylic acid amides Amino acids Monocarboxylic acids and derivatives Carboxylic acids Azacyclic compounds Organopnictogen compounds Organic oxides Monoalkylamines Hydrocarbon derivatives Carbonyl compounds |
| Molecular Framework | Aromatic heteromonocyclic compounds |
| Substituents | Hybrid peptide - Histidine or derivatives - N-acyl-alpha-amino acid - N-acyl-alpha amino acid or derivatives - N-acyl-l-alpha-amino acid - Beta amino acid or derivatives - Alpha-amino acid or derivatives - Imidazolyl carboxylic acid derivative - Azole - Heteroaromatic compound - Imidazole - Amino acid - Amino acid or derivatives - Secondary carboxylic acid amide - Carboxamide group - Azacycle - Organoheterocyclic compound - Carboxylic acid derivative - Carboxylic acid - Monocarboxylic acid or derivatives - Organopnictogen compound - Primary aliphatic amine - Organic nitrogen compound - Amine - Organonitrogen compound - Organooxygen compound - Carbonyl group - Primary amine - Hydrocarbon derivative - Organic oxygen compound - Organic oxide - Aromatic heteromonocyclic compound |
| Description | This compound belongs to the class of organic compounds known as hybrid peptides. These are compounds containing at least two different types of amino acids (alpha, beta, gamma, delta) linked to each other through a peptide bond. |
| External Descriptors | dipeptide |
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Find and download the COA for your product by matching the lot number on the packaging.
| Lot Number | Certificate Type | Date | Item |
|---|---|---|---|
| Certificate of Analysis | Apr 07, 2026 | C106843 | |
| Certificate of Analysis | Mar 12, 2026 | C106843 | |
| Certificate of Analysis | Mar 12, 2026 | C106843 | |
| Certificate of Analysis | Mar 12, 2026 | C106843 | |
| Certificate of Analysis | Mar 12, 2026 | C106843 | |
| Certificate of Analysis | Sep 28, 2025 | C106843 | |
| Certificate of Analysis | Sep 28, 2025 | C106843 | |
| Certificate of Analysis | Sep 28, 2025 | C106843 | |
| Certificate of Analysis | Sep 28, 2025 | C106843 | |
| Certificate of Analysis | Jan 18, 2025 | C106843 | |
| Certificate of Analysis | Jan 18, 2025 | C106843 | |
| Certificate of Analysis | Jan 18, 2025 | C106843 | |
| Certificate of Analysis | Jan 18, 2025 | C106843 | |
| Certificate of Analysis | Jan 18, 2025 | C106843 | |
| Certificate of Analysis | Jan 18, 2025 | C106843 | |
| Certificate of Analysis | Jan 18, 2025 | C106843 | |
| Certificate of Analysis | Oct 24, 2024 | C106843 | |
| Certificate of Analysis | Oct 24, 2024 | C106843 | |
| Certificate of Analysis | Oct 24, 2024 | C106843 | |
| Certificate of Analysis | Oct 24, 2024 | C106843 | |
| Certificate of Analysis | Feb 04, 2024 | C106843 | |
| Certificate of Analysis | Feb 04, 2024 | C106843 | |
| Certificate of Analysis | Feb 04, 2024 | C106843 | |
| Certificate of Analysis | Feb 04, 2024 | C106843 | |
| Certificate of Analysis | Aug 12, 2023 | C106843 | |
| Certificate of Analysis | Aug 12, 2023 | C106843 | |
| Certificate of Analysis | Aug 12, 2023 | C106843 | |
| Certificate of Analysis | Jun 10, 2022 | C106843 | |
| Certificate of Analysis | Jun 10, 2022 | C106843 | |
| Certificate of Analysis | Jun 10, 2022 | C106843 | |
| Certificate of Analysis | Jun 10, 2022 | C106843 | |
| Certificate of Analysis | Jun 07, 2021 | C106843 | |
| Certificate of Analysis | Jun 07, 2021 | C106843 | |
| Certificate of Analysis | Jun 07, 2021 | C106843 | |
| Certificate of Analysis | Jun 07, 2021 | C106843 |
| Solubility | Soluble in 80% acetic acid (10 mg/ml), and water (1:3.1). |
|---|---|
| Sensitivity | Hygroscopic;air sensitive |
| Specific Rotation[α] | 21 ° (C=2, H2O) |
| Melt Point(°C) | 253°C |
| Molecular Weight | 226.230 g/mol |
| XLogP3 | -4.000 |
| Hydrogen Bond Donor Count | 4 |
| Hydrogen Bond Acceptor Count | 5 |
| Rotatable Bond Count | 6 |
| Exact Mass | 226.107 Da |
| Monoisotopic Mass | 226.107 Da |
| Topological Polar Surface Area | 121.000 Ų |
| Heavy Atom Count | 16 |
| Formal Charge | 0 |
| Complexity | 259.000 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 1 |
| Undefined Atom Stereocenter Count | 0 |
| Defined Bond Stereocenter Count | 0 |
| Undefined Bond Stereocenter Count | 0 |
| The total count of all stereochemical bonds | 0 |
| Covalently-Bonded Unit Count | 1 |
| 1. Wei Jia, Jiying Zhu. (2023) Molecular Mechanism of ε-Polylysine Treatment of Animal-Derived Foods: Glycine Amidinotransferase Activity Implicates Upregulation of l-Arginine and Creatine. JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, [PMID:37793042] [10.1021/acs.jafc.3c04033] |
| 2. Tian Hao, Zhimin Yang, Jianfeng Liang, Jingjin Yu, Jun Liu. (2023) Foliar Application of Carnosine and Chitosan Improving Drought Tolerance in Bermudagrass. Agronomy-Basel, 13 (2): (442). [PMID:] [10.3390/agronomy13020442] |
| 3. Qi Yue, Xu Xinglian, Dong Hualin, Yang Zongyun, Wang Peng. (2022) Insight Into the Effect of Carnosine on the Dispersibility of Myosin Under a Low-salt Condition and its Mechanism. Food Biophysics, 18 (1): (71-81). [PMID:] [10.1007/s11483-022-09747-6] |
| 4. Yali Chen, Ling Xia, Xiaohua Xiao, Gongke Li. (2022) Enhanced capillary zone electrophoresis in cyclic olefin copolymer microchannels using the combination of dynamic and static coatings for rapid analysis of carnosine and niacinamide in cosmetics. JOURNAL OF SEPARATION SCIENCE, 45 (12): (2045-2054). [PMID:35324077] [10.1002/jssc.202101007] |
| 5. Junyang Xu, Yanjun Jiang, Liya Zhou, Li Ma, Zhihong Huang, Jiafu Shi, Jing Gao, Ying He. (2021) Nickel-Carnosine complex: A new carrier for enzymes immobilization by affinity adsorption. CHINESE JOURNAL OF CHEMICAL ENGINEERING, [PMID:] [10.1016/j.cjche.2021.04.019] |
| 6. He Qi, Zheng Li, Haijiao Zheng, Qiong Jia. (2021) Carnosine functionalized magnetic metal–organic framework nanocomposites for synergistic enrichment of phosphopeptides. ANALYTICA CHIMICA ACTA, [PMID:33832591] [10.1016/j.aca.2021.338383] |
| 7. Lili Zhang, Wen Duan, Yan Huang, Yuyu Zhang, Baoguo Sun, Dandan Pu, Yizhuang Tang, Chao Liu. (2020) Sensory taste properties of chicken (Hy-Line brown) soup as prepared with five different parts of the chicken. INTERNATIONAL JOURNAL OF FOOD PROPERTIES, [PMID:] [10.1080/10942912.2020.1828455] |
| 8. Liu Pei, Yan Xu, Jiaqiang Liu, Junbiao Wu, Yide Han, Xia Zhang. (2019) Effects of solvent-induced morphology evolution of Zn2GeO4 on photocatalytic activities of g-C3N4/Zn2GeO4 composites. JOURNAL OF THE AMERICAN CERAMIC SOCIETY, 102 (11): (6517-6528). [PMID:] [10.1111/jace.16605] |
| 9. Wei Wang, Ruiguang Bai, Xiaoyu Cai, Ping Lin, Lihong Ma. (2017) Separation and determination of peptide metabolite of Bacillus licheniformis in a microbial fuel cell by high-speed capillary micellar electrokinetic chromatography. JOURNAL OF SEPARATION SCIENCE, 40 (22): (4446-4452). [PMID:28960829] [10.1002/jssc.201700656] |
| 10. Chusheng Liu, Haibin Li, Qiqin Wang, Jacques Crommen, Haibo Zhou, Zhengjin Jiang. (2017) Preparation and evaluation of 400 μm I.D. polymer-based hydrophilic interaction chromatography monolithic columns with high column efficiency. JOURNAL OF CHROMATOGRAPHY A, [PMID:28629939] [10.1016/j.chroma.2017.06.034] |
| 11. Hongji Li, Xiao Wei, Yeqing Xu, Kai Lu, Yufeng Zhang, Yongsheng Yan, Chunxiang Li. (2016) A thin shell and “sunny shape” molecular imprinted fluorescence sensor in selective detection of trace level pesticides in river. JOURNAL OF ALLOYS AND COMPOUNDS, [PMID:] [10.1016/j.jallcom.2016.12.239] |
| 12. Ru Song, Kai-qiang Zhang, Rong-bian Wei. (2016) In vitro antioxidative activities of squid (Ommastrephes bartrami) viscera autolysates and identification of active peptides. PROCESS BIOCHEMISTRY, [PMID:] [10.1016/j.procbio.2016.06.015] |
| 13. Wei Wang, Lihong Ma, Ping Lin, Kaixuan Xu. (2016) Separation and detection of amino acid metabolites of Escherichia coli in microbial fuel cell with CE. ELECTROPHORESIS, 37 (14): (2106-2111). [PMID:27121957] [10.1002/elps.201600007] |
| 14. Xing Chen, Yufeng Zou, Minyi Han, Lihua Pan, Tong Xing, Xinglian Xu, Guanghong Zhou. (2015) Solubilisation of myosin in a solution of low ionic strength l-histidine: Significance of the imidazole ring. FOOD CHEMISTRY, [PMID:26593463] [10.1016/j.foodchem.2015.09.039] |
| 15. Lu Wang, Limei Xiao, Shoujing Zheng, Jie Pang, Jiebo Chen. (2024) Characterization and assessment of free amino acids in different varieties of sugarcane. INDUSTRIAL CROPS AND PRODUCTS, [PMID:] [10.1016/j.indcrop.2024.118306] |
| 16. Shang Chi, Yaping Li, Tingting Ye, Jiawei Kang, Zhihui Xiang, Xiaoqing Kuang, Chenggang Yi, Yiying Qi, Wei Wang. (2025) Energy reconversion of ultrasound on a piezoelectric hydrogel promotes ROS/CO generation and wound self-closure for infected chronic wound healing. Matter, [PMID:] [10.1016/j.matt.2025.101989] |
| 17. Siyu Wu, Xiaojuan Niu, Jiali Chen, Wangni Meng, Han Tao, Jianli Zhou, Yuangen Wu. (2025) Design of Mn-Car multivalent laccase mimics through self-assembled coordination and its application for ultrasensitive colorimetric detection of kanamycin in food. MICROCHEMICAL JOURNAL, [PMID:] [10.1016/j.microc.2025.114523] |
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