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Glucagon receptor (GCGR)

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  1. hGCGR Antagonist, Antagonist of glukagon receptor
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    hGCGR Antagonist, Antagonist of glukagon receptor
    CAS: 438618-32-7 Formula: C20H30N2OS Molecular Weight: 346.5
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥95%
    Out of Stock Item #: G338729
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    IUPAC Name
    N-[3-cyano-6-(2-methylbutan-2-yl)-4,5,6,7-tetrahydro-1-benzothiophen-2-yl]-2-ethylbutanamide
    SMILES
    CCC(CC)C(=O)NC1=C(C2=C(S1)CC(CC2)C(C)(C)CC)C#N
    InChIKey
    SWIBDWBSJSJQHL-UHFFFAOYSA-N
    InChI
    1S/C20H30N2OS/c1-6-13(7-2)18(23)22-19-16(12-21)15-10-9-14(11-17(15)24-19)20(4,5)8-3/h13-14H,6-11H2,1-5H3,(H,22,23)
    Synonyms
    MFCD01920208 | NCGC00340210-02 | AKOS017343007 | N-[3-cyano-6-(2-methylbutan-2-yl)-4,5,6,7-tetrahydro-1-benzothiophen...
  2. VU 0650991
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    VU 0650991
    CAS: 488097-06-9 EC Number: 963-629-8 PubChem CID: 1941609 Formula: C16H11ClF6N4O2 Molecular Weight: 440.73
    ≥98%(HPLC)
    Out of Stock Item #: V288056
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    IUPAC Name
    7-(4-chlorophenyl)-1,3-dimethyl-5,5-bis(trifluoromethyl)-8H-pyrimido[4,5-d]pyrimidine-2,4-dione
    SMILES
    CN1C2=C(C(=O)N(C1=O)C)C(N=C(N2)C3=CC=C(C=C3)Cl)(C(F)(F)F)C(F)(F)F
    InChIKey
    MFEIZMHODFOWAT-UHFFFAOYSA-N
    InChI
    1S/C16H11ClF6N4O2/c1-26-11-9(12(28)27(2)13(26)29)14(15(18,19)20,16(21,22)23)25-10(24-11)7-3-5-8(17)6-4-7/h3-6H,1-2H3,(H,24,25)
    Synonyms
    7-(4-Chlorophenyl)-5,8-dihydro-1,3-dimethyl-5,5-bis(trifluoromethyl)pyrimido[4,5-d]pyrimidine-2,4(1H,3H)-dione
  3. L-168,049, Antagonist of glukagon receptor
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    L-168,049, Antagonist of glukagon receptor
    CAS: 191034-25-0 Formula: C24H20BrClN2O Molecular Weight: 467.79
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥99%(HPLC)
    In Stock Item #: L287004
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    IUPAC Name
    4-[3-(5-bromo-2-propoxyphenyl)-5-(4-chlorophenyl)-1H-pyrrol-2-yl]pyridine
    SMILES
    CCCOC1=C(C=C(C=C1)Br)C2=C(NC(=C2)C3=CC=C(C=C3)Cl)C4=CC=NC=C4
    InChIKey
    HHBOWXZOLYQFNY-UHFFFAOYSA-N
    InChI
    1S/C24H20BrClN2O/c1-2-13-29-23-8-5-18(25)14-20(23)21-15-22(16-3-6-19(26)7-4-16)28-24(21)17-9-11-27-12-10-17/h3-12,14-15,28H,2,13H2,1H3
    Synonyms
    4-[(2-amino-4-oxo-3H-pteridin-6-yl)methyl-(2,2,2-trifluoroacetyl)amino]benzoic acid | 4-[3-(5-Bromo-2-propoxy-phenyl)...
  4. Adomeglivant, Antagonist of glukagon receptor
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    Adomeglivant, Antagonist of glukagon receptor
    CAS: 1488363-78-5 Formula: C32H36F3NO4 Molecular Weight: 555.63
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. 10mM in DMSO
    In Stock Item #: A421743
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    IUPAC Name
    3-[[4-[(1S)-1-[4-(4-tert-butylphenyl)-3,5-dimethylphenoxy]-4,4,4-trifluorobutyl]benzoyl]amino]propanoic acid
    SMILES
    CC1=CC(=CC(=C1C2=CC=C(C=C2)C(C)(C)C)C)OC(CCC(F)(F)F)C3=CC=C(C=C3)C(=O)NCCC(=O)O
    InChIKey
    FASLTMSUPQDLIB-MHZLTWQESA-N
    InChI
    1S/C32H36F3NO4/c1-20-18-26(19-21(2)29(20)23-10-12-25(13-11-23)31(3,4)5)40-27(14-16-32(33,34)35)22-6-8-24(9-7-22)30(39)36-17-15-28(37)38/h6-13,18-19,27show more
    Synonyms
    F85410 | AKOS040741049 | FASLTMSUPQDLIB-MHZLTWQESA-N | A858152 | ADOMEGLIVANT [WHO-DD] | .BETA.-ALANINE, N-(4-((1S)-1...
  5. Adomeglivant - Moligand™, ≥98% CAS No(1488363-78-5) by Aladdin Scientific
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    Adomeglivant, Antagonist of glukagon receptor
    CAS: 1488363-78-5 Formula: C32H36F3NO4 Molecular Weight: 555.63
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    In Stock Item #: A412451
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    IUPAC Name
    3-[[4-[(1S)-1-[4-(4-tert-butylphenyl)-3,5-dimethylphenoxy]-4,4,4-trifluorobutyl]benzoyl]amino]propanoic acid
    SMILES
    CC1=CC(=CC(=C1C2=CC=C(C=C2)C(C)(C)C)C)OC(CCC(F)(F)F)C3=CC=C(C=C3)C(=O)NCCC(=O)O
    InChIKey
    FASLTMSUPQDLIB-MHZLTWQESA-N
    InChI
    1S/C32H36F3NO4/c1-20-18-26(19-21(2)29(20)23-10-12-25(13-11-23)31(3,4)5)40-27(14-16-32(33,34)35)22-6-8-24(9-7-22)30(39)36-17-15-28(37)38/h6-13,18-19,27show more
    Synonyms
    F85410 | AKOS040741049 | FASLTMSUPQDLIB-MHZLTWQESA-N | A858152 | ADOMEGLIVANT [WHO-DD] | .BETA.-ALANINE, N-(4-((1S)-1...
  6. GRA Ex-25
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    GRA Ex-25
    CAS: 307983-31-9 Formula: C29H36F3N3O5 Molecular Weight: 563.61
    ≥98%
    In Stock Item #: G412374
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    IUPAC Name
    3-[[4-[[(4-tert-butylcyclohexyl)-[[4-(trifluoromethoxy)phenyl]carbamoyl]amino]methyl]benzoyl]amino]propanoic acid
    SMILES
    CC(C)(C)C1CCC(CC1)N(CC2=CC=C(C=C2)C(=O)NCCC(=O)O)C(=O)NC3=CC=C(C=C3)OC(F)(F)F
    InChIKey
    BZXMLCVDKDXRQY-UHFFFAOYSA-N
    InChI
    1S/C29H36F3N3O5/c1-28(2,3)21-8-12-23(13-9-21)35(27(39)34-22-10-14-24(15-11-22)40-29(30,31)32)18-19-4-6-20(7-5-19)26(38)33-17-16-25(36)37/h4-7,10-11,14show more
  7. no_selection
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    BAY27-9955, Antagonist of glukagon receptor
    CAS: 202855-56-9 Formula: C23H31FO Molecular Weight: 342.49
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    In Stock Item #: B607939
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    IUPAC Name
    1-[2-(4-fluorophenyl)-4,6-di(propan-2-yl)-3-propylphenyl]ethanol
    SMILES
    CCCc1c(cc(c(c1c1ccc(cc1)F)C(O)C)C(C)C)C(C)C
    InChIKey
    VDTWKXAPIQBOMO-UHFFFAOYSA-N
    InChI
    1S/C23H31FO/c1-7-8-19-20(14(2)3)13-21(15(4)5)22(16(6)25)23(19)17-9-11-18(24)12-10-17/h9-16,25H,7-8H2,1-6H3
    Synonyms
    BAY-279955 | BAY-27-9955 | BAY27-9955 | UNII-8YYY3F3G47 | 1-(4'-fluoro-3,5-diisopropyl-6-propyl-[1,1'-biphenyl]-2-yl)...
  8. no_selection
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    MK-0893, Glukagon receptor antagonist
    CAS: 870823-12-4 Formula: C32H27Cl2N3O4 Molecular Weight: 588.48
    Solid Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    In Stock Item #: M611910
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    IUPAC Name
    3-[[4-[(1S)-1-[3-(3,5-dichlorophenyl)-5-(6-methoxynaphthalen-2-yl)pyrazol-1-yl]ethyl]benzoyl]amino]propanoic acid
    SMILES
    CC(C1=CC=C(C=C1)C(=O)NCCC(=O)O)N2C(=CC(=N2)C3=CC(=CC(=C3)Cl)Cl)C4=CC5=C(C=C4)C=C(C=C5)OC
    InChIKey
    DNTVJEMGHBIUMW-IBGZPJMESA-N
    InChI
    1S/C32H27Cl2N3O4/c1-19(20-3-5-21(6-4-20)32(40)35-12-11-31(38)39)37-30(18-29(36-37)25-14-26(33)17-27(34)15-25)24-8-7-23-16-28(41-2)10-9-22(23)13-24/h3-show more
    Synonyms
    (S)-3-(4-(1-(3-(3,5-Dichlorophenyl)-5-(6-methoxynaphthalen-2-yl)-1H-pyrazol-1-yl)ethyl)benzamido)propanoic acid | BDB...
  9. no_selection
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    NNC 92-1687, Antagonist of glukagon receptor
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools.
    Out of Stock Item #: N612343
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    IUPAC Name
    2-(1H-benzimidazol-2-ylsulfanyl)-1-(3,4-dihydroxyphenyl)ethanone
    SMILES
    O=C(c1ccc(c(c1)O)O)CSc1nc2c([nH]1)cccc2
    InChIKey
    NVYSVDRYESXWBD-UHFFFAOYSA-N
    InChI
    1S/C15H12N2O3S/c18-12-6-5-9(7-13(12)19)14(20)8-21-15-16-10-3-1-2-4-11(10)17-15/h1-7,18-19H,8H2,(H,16,17)
    Synonyms
    NNC92-1687
  11. PF-06291874, Glukagon receptor antagonist
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    PF-06291874, Glukagon receptor antagonist
    CAS: 1393124-08-7 PubChem CID: 60151939 Formula: C26H28F3N3O4 Molecular Weight: 503.51
    ≥99%
    Out of Stock Item #: P651142
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    IUPAC Name
    3-[[4-[(1S)-1-[3,5-dimethyl-4-[4-(trifluoromethyl)pyrazol-1-yl]phenoxy]butyl]benzoyl]amino]propanoic acid
    SMILES
    CCCC(C1=CC=C(C=C1)C(=O)NCCC(=O)O)OC2=CC(=C(C(=C2)C)N3C=C(C=N3)C(F)(F)F)C
    InChIKey
    IBDYYOQKQCCSDP-QFIPXVFZSA-N
    InChI
    1S/C26H28F3N3O4/c1-4-5-22(18-6-8-19(9-7-18)25(35)30-11-10-23(33)34)36-21-12-16(2)24(17(3)13-21)32-15-20(14-31-32)26(27,28)29/h6-9,12-15,22H,4-5,10-11Hshow more
    Synonyms
    .BETA.-ALANINE, N-(4-((1S)-1-(3,5-DIMETHYL-4-(4-(TRIFLUOROMETHYL)-1H-PYRAZOL-1-YL)PHENOXY)BUTYL)BENZOYL)- | BDBM50433...
  12. 4-[2-(2-bromophenyl)-4-(4-fluorophenyl)-1H-imidazol-5-yl]Pyridine
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    4-[2-(2-bromophenyl)-4-(4-fluorophenyl)-1H-imidazol-5-yl]Pyridine
    CAS: 384820-17-1 PubChem CID: 9886904 Formula: C20H13BrFN3 Molecular Weight: 394.2
    Out of Stock Item #: B669027
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    Technical Identifiers
    IUPAC Name
    4-[2-(2-bromophenyl)-4-(4-fluorophenyl)-1H-imidazol-5-yl]pyridine
    SMILES
    C1=CC=C(C(=C1)C2=NC(=C(N2)C3=CC=NC=C3)C4=CC=C(C=C4)F)Br
    InChIKey
    COVWDRBCMJOSQM-UHFFFAOYSA-N
    InChI
    1S/C20H13BrFN3/c21-17-4-2-1-3-16(17)20-24-18(13-5-7-15(22)8-6-13)19(25-20)14-9-11-23-12-10-14/h1-12H,(H,24,25)
    Synonyms
    4-[2-(2-bromophenyl)-4-(4-fluorophenyl)-1H-imidazol-5-yl]Pyridine | 4-[2-(2-BROMOPHENYL)-5-(4-FLUOROPHENYL)-1H-IMIDAZ...
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