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Sodium channel protein type 10 subunit alpha (SCN10A)

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  1. PF 04885614, Inhibitor of K v11.1;Inhibitor of Na v1.6;Inhibitor of Na v1.8
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    PF 04885614, Inhibitor of K v11.1;Inhibitor of Na v1.6;Inhibitor of Na v1.8
    CAS: 1480833-70-2 PubChem CID: 65459349 Formula: C13H14F3N3O Molecular Weight: 285.26
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%(HPLC)
    In Stock Item #: P288823
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    Technical Identifiers
    IUPAC Name
    2-[5-[4-(trifluoromethoxy)phenyl]-1H-imidazol-2-yl]propan-2-amine
    SMILES
    CC(C)(C1=NC=C(N1)C2=CC=C(C=C2)OC(F)(F)F)N
    InChIKey
    AGORGFNWYAUYSU-UHFFFAOYSA-N
    InChI
    1S/C13H14F3N3O/c1-12(2,17)11-18-7-10(19-11)8-3-5-9(6-4-8)20-13(14,15)16/h3-7H,17H2,1-2H3,(H,18,19)
    Synonyms
    1-Methyl-[1-[4-(4-trifluoromethoxy)phenyl]-imidazol-2-yl]-ethanamine
  2. ICA 121431
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    ICA 121431
    CAS: 313254-51-2 EC Number: 809-095-0 Formula: C23H19N3O3S2 Molecular Weight: 449.55
    ≥98%(HPLC)
    Out of Stock Item #: I287555
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    IUPAC Name
    2,2-diphenyl-N-[4-(1,3-thiazol-2-ylsulfamoyl)phenyl]acetamide
    SMILES
    C1=CC=C(C=C1)C(C2=CC=CC=C2)C(=O)NC3=CC=C(C=C3)S(=O)(=O)NC4=NC=CS4
    InChIKey
    URSQNPPONHUJDL-UHFFFAOYSA-N
    InChI
    1S/C23H19N3O3S2/c27-22(21(17-7-3-1-4-8-17)18-9-5-2-6-10-18)25-19-11-13-20(14-12-19)31(28,29)26-23-24-15-16-30-23/h1-16,21H,(H,24,26)(H,25,27)
    Synonyms
    F0012-0842 | Oprea1_750763 | 2,2-DIPHENYL-N-{4-[(1,3-THIAZOL-2-YL)SULFAMOYL]PHENYL}ACETAMIDE | BDBM50118516 | BCP2861...
  3. A-803467, Channel blocker of Na v1.8
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    A-803467, Channel blocker of Na v1.8
    CAS: 944261-79-4 EC Number: 687-382-8 Formula: C19H16ClNO4 Molecular Weight: 357.79
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    In Stock Item #: A127941
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    IUPAC Name
    5-(4-chlorophenyl)-N-(3,5-dimethoxyphenyl)furan-2-carboxamide
    SMILES
    COC1=CC(=CC(=C1)NC(=O)C2=CC=C(O2)C3=CC=C(C=C3)Cl)OC
    InChIKey
    VHKBTPQDHDSBSP-UHFFFAOYSA-N
    InChI
    1S/C19H16ClNO4/c1-23-15-9-14(10-16(11-15)24-2)21-19(22)18-8-7-17(25-18)12-3-5-13(20)6-4-12/h3-11H,1-2H3,(H,21,22)
    Synonyms
    MFCD10574689 | 5-(4-chlorophenyl)-N-(3,5-dimethoxyphenyl)-2-furamide | AS-55982 | N-t-butoxycarbonyl-S-tritylcysteine...
  4. Eleclazine, Inhibitor of Na v1.5
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    Eleclazine, Inhibitor of Na v1.5
    CAS: 1443211-72-0 Formula: C21H16F3N3O3 Molecular Weight: 415.372
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥97%
    In Stock Item #: E174249
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    IUPAC Name
    4-(pyrimidin-2-ylmethyl)-7-[4-(trifluoromethoxy)phenyl]-2,3-dihydro-1,4-benzoxazepin-5-one
    SMILES
    C1COC2=C(C=C(C=C2)C3=CC=C(C=C3)OC(F)(F)F)C(=O)N1CC4=NC=CC=N4
    InChIKey
    YNUAEEJQYHYLMS-UHFFFAOYSA-N
    InChI
    1S/C21H16F3N3O3/c22-21(23,24)30-16-5-2-14(3-6-16)15-4-7-18-17(12-15)20(28)27(10-11-29-18)13-19-25-8-1-9-26-19/h1-9,12H,10-11,13H2
    Synonyms
    Eleclazine|1443211-72-0|GS-6615|Eleclazine [INN]|4-(pyrimidin-2-ylmethyl)-7-(4-(trifluoromethoxy)phenyl)-3,4-dihydrob...
  5. A-803467, Channel blocker of Na v1.8
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    A-803467, Channel blocker of Na v1.8
    CAS: 944261-79-4 EC Number: 687-382-8 Formula: C19H16ClNO4 Molecular Weight: 357.79
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. 10mM in DMSO
    In Stock Item #: A409222
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    Technical Identifiers
    Synonyms
    5-(4-chlorophenyl)-N-(3,5-dimethoxyphenyl)furan-2-carboxamide
  6. VX-150
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    VX-150
    CAS: 1793080-72-4 PubChem CID: 118126601 Formula: C21H17F4N2O7P Molecular Weight: 516.34
    ≥98%
    In Stock Item #: V412695
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    Technical Identifiers
    IUPAC Name
    [4-[[2-(4-fluoro-2-methylphenoxy)-4-(trifluoromethyl)benzoyl]amino]-2-oxopyridin-1-yl]methyl dihydrogen phosphate
    SMILES
    CC1=C(C=CC(=C1)F)OC2=C(C=CC(=C2)C(F)(F)F)C(=O)NC3=CC(=O)N(C=C3)COP(=O)(O)O
    InChIKey
    SQDQNNKQTHOQHO-UHFFFAOYSA-N
    InChI
    1S/C21H17F4N2O7P/c1-12-8-14(22)3-5-17(12)34-18-9-13(21(23,24)25)2-4-16(18)20(29)26-15-6-7-27(19(28)10-15)11-33-35(30,31)32/h2-10H,11H2,1H3,(H,26,29)(Hshow more
    Synonyms
    EOS-62073
  7. VX-150
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    VX-150
    CAS: 1793080-72-4 PubChem CID: 118126601 Formula: C21H17F4N2O7P Molecular Weight: 516.34
    10mM in DMSO
    In Stock Item #: V422186
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    Pricing & Pack Sizes
    Technical Identifiers
    IUPAC Name
    [4-[[2-(4-fluoro-2-methylphenoxy)-4-(trifluoromethyl)benzoyl]amino]-2-oxopyridin-1-yl]methyl dihydrogen phosphate
    SMILES
    CC1=C(C=CC(=C1)F)OC2=C(C=CC(=C2)C(F)(F)F)C(=O)NC3=CC(=O)N(C=C3)COP(=O)(O)O
    InChIKey
    SQDQNNKQTHOQHO-UHFFFAOYSA-N
    InChI
    1S/C21H17F4N2O7P/c1-12-8-14(22)3-5-17(12)34-18-9-13(21(23,24)25)2-4-16(18)20(29)26-15-6-7-27(19(28)10-15)11-33-35(30,31)32/h2-10H,11H2,1H3,(H,26,29)(Hshow more
    Synonyms
    EOS-62073
  8. ABBV-318, Channel blocker of Na v1.7;Channel blocker of Na v1.8
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    ABBV-318, Channel blocker of Na v1.7;Channel blocker of Na v1.8
    CAS: 1802848-94-7 Formula: C20H15F4N3O2 Molecular Weight: 405.35
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    In Stock Item #: A607321
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    Technical Identifiers
    Synonyms
    ABBV318;compound 73
  9. no_selection
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    PF-01247324, Channel blocker of Na v1.8
    CAS: 875051-72-2 EC Number: 109-926-0 PubChem CID: 11659955 Formula: C13H10Cl3N3O Molecular Weight: 330.6
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools.
    Out of Stock Item #: P612721
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    Technical Identifiers
    IUPAC Name
    6-amino-N-methyl-5-(2,3,5-trichlorophenyl)pyridine-2-carboxamide
    SMILES
    CNC(=O)C1=NC(=C(C=C1)C2=C(C(=CC(=C2)Cl)Cl)Cl)N
    InChIKey
    HPIUHDCRVYDAEJ-UHFFFAOYSA-N
    InChI
    1S/C13H10Cl3N3O/c1-18-13(20)10-3-2-7(12(17)19-10)8-4-6(14)5-9(15)11(8)16/h2-5H,1H3,(H2,17,19)(H,18,20)
    Synonyms
    BCP29090 | HY-101383 | SCHEMBL3463441 | DTXSID40470208 | EX-A2501 | Q27088308 | AKOS027423927 | 6-amino-N-methyl-5-(2...
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