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Ephrin type-a receptor 2 (EPHA2)

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  1. ALW-II-41-27 - ≥98% CAS No(1186206-79-0) by Aladdin Scientific
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    ALW-II-41-27
    CAS: 1186206-79-0 Formula: C32H32F3N5O2S Molecular Weight: 607.69
    ≥98%
    In Stock Item #: A127683
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    Technical Identifiers
    IUPAC Name
    N-[5-[[4-[(4-ethylpiperazin-1-yl)methyl]-3-(trifluoromethyl)phenyl]carbamoyl]-2-methylphenyl]-5-thiophen-2-ylpyridine-3-carboxamide
    SMILES
    CCN1CCN(CC1)CC2=C(C=C(C=C2)NC(=O)C3=CC(=C(C=C3)C)NC(=O)C4=CN=CC(=C4)C5=CC=CS5)C(F)(F)F
    InChIKey
    HYWXBDQAYLPMIX-UHFFFAOYSA-N
    InChI
    1S/C32H32F3N5O2S/c1-3-39-10-12-40(13-11-39)20-23-8-9-26(17-27(23)32(33,34)35)37-30(41)22-7-6-21(2)28(16-22)38-31(42)25-15-24(18-36-19-25)29-5-4-14-43-show more
    Synonyms
    EX-A2618 | ALW-II-41-27 | HMS3333E20 | BCP26205 | HMS2043H01 | HY-18007 | SCHEMBL20136698 | N-[5-({4-[(4-Ethylpiperaz...
  2. Alisertib (MLN8237), Serine/threonine-protein kinase Aurora-A inhibitor
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    Alisertib (MLN8237), Serine/threonine-protein kinase Aurora-A inhibitor
    CAS: 1028486-01-2 Formula: C27H20ClFN4O4 Molecular Weight: 518.94
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    In Stock Item #: A126379
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    Technical Identifiers
    IUPAC Name
    4-[[9-chloro-7-(2-fluoro-6-methoxyphenyl)-5H-pyrimido[5,4-d][2]benzazepin-2-yl]amino]-2-methoxybenzoic acid
    SMILES
    COC1=C(C(=CC=C1)F)C2=NCC3=CN=C(N=C3C4=C2C=C(C=C4)Cl)NC5=CC(=C(C=C5)C(=O)O)OC
    InChIKey
    ZLHFILGSQDJULK-UHFFFAOYSA-N
    InChI
    1S/C27H20ClFN4O4/c1-36-21-5-3-4-20(29)23(21)25-19-10-15(28)6-8-17(19)24-14(12-30-25)13-31-27(33-24)32-16-7-9-18(26(34)35)22(11-16)37-2/h3-11,13H,12H2,show more
    Synonyms
    Alisertib | MLN8237 | MLN-8237 | UNII-O3FX965V0I | MLN8237 (Alisertib) | FT-0672433 | Alisertib (USAN) | Alisertib; M...
  3. Dorsomorphin, Inhibitor of EPH receptor A2;Inhibitor of fms related receptor tyrosine kinase 1;Inhibitor of fms related receptor tyrosine kinase 3;Inhibitor of kinase insert domain receptor;Inhibitor of LCK proto-oncogene; Src family tyrosine kinase;Inhibitor of MAPK i
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    Dorsomorphin, Inhibitor of EPH receptor A2;Inhibitor of fms related receptor tyrosine kinase 1;Inhibitor of fms related receptor tyrosine kinase 3;Inhibitor of kinase insert domain receptor;Inhibitor of LCK proto-oncogene; Src family tyrosine kinase;Inhibitor of MAPK i
    CAS: 866405-64-3 EC Number: 635-949-5 Formula: C24H25N5O Molecular Weight: 399.49
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    In Stock Item #: D139352
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    IUPAC Name
    6-[4-(2-piperidin-1-ylethoxy)phenyl]-3-pyridin-4-ylpyrazolo[1,5-a]pyrimidine
    SMILES
    C1CCN(CC1)CCOC2=CC=C(C=C2)C3=CN4C(=C(C=N4)C5=CC=NC=C5)N=C3
    InChIKey
    XHBVYDAKJHETMP-UHFFFAOYSA-N
    InChI
    1S/C24H25N5O/c1-2-12-28(13-3-1)14-15-30-22-6-4-19(5-7-22)21-16-26-24-23(17-27-29(24)18-21)20-8-10-25-11-9-20/h4-11,16-18H,1-3,12-15H2
    Synonyms
    6-[4-(2-piperidin-1-ylethoxy)phenyl]-3-pyridin-4-yl-pyrazolo[1,5-a]pyrimidine | AC-27419 | SY256013 | AM20061004 | Do...
  4. FMK, Inhibitor of ribosomal protein S6 kinase A3
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    FMK, Inhibitor of ribosomal protein S6 kinase A3
    CAS: 821794-92-7 Formula: C18H19FN4O2 Molecular Weight: 342.37
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    In Stock Item #: F127391
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    IUPAC Name
    1-[4-amino-7-(3-hydroxypropyl)-5-(4-methylphenyl)pyrrolo[2,3-d]pyrimidin-6-yl]-2-fluoroethanone
    SMILES
    CC1=CC=C(C=C1)C2=C(N(C3=NC=NC(=C23)N)CCCO)C(=O)CF
    InChIKey
    IKLGYJACVCXYIL-UHFFFAOYSA-N
    InChI
    1S/C18H19FN4O2/c1-11-3-5-12(6-4-11)14-15-17(20)21-10-22-18(15)23(7-2-8-24)16(14)13(25)9-19/h3-6,10,24H,2,7-9H2,1H3,(H2,20,21,22)
    Synonyms
    BDBM50248765 | MFCD22417081 | 1-[4-Amino-7-(3-hydroxypropyl)-5-(4-methylphenyl)-7H-pyrrolo[2,3-d]pyrimidin-6-yl]-2-fl...
  5. LY 3009120, Inhibitor of A-Raf proto-oncogene; serine/threonine kinase;Inhibitor of B-Raf proto-oncogene; serine/threonine kinase;Inhibitor of Raf-1 proto-oncogene; serine/threonine kinase
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    LY 3009120, Inhibitor of A-Raf proto-oncogene; serine/threonine kinase;Inhibitor of B-Raf proto-oncogene; serine/threonine kinase;Inhibitor of Raf-1 proto-oncogene; serine/threonine kinase
    CAS: 1454682-72-4 Formula: C23H29FN6O Molecular Weight: 424.52
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%(HPLC)
    In Stock Item #: L288815
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    Technical Identifiers
    IUPAC Name
    1-(3,3-dimethylbutyl)-3-[2-fluoro-4-methyl-5-[7-methyl-2-(methylamino)pyrido[2,3-d]pyrimidin-6-yl]phenyl]urea
    SMILES
    CC1=CC(=C(C=C1C2=C(N=C3C(=C2)C=NC(=N3)NC)C)NC(=O)NCCC(C)(C)C)F
    InChIKey
    HHCBMISMPSAZBF-UHFFFAOYSA-N
    InChI
    1S/C23H29FN6O/c1-13-9-18(24)19(29-22(31)26-8-7-23(3,4)5)11-16(13)17-10-15-12-27-21(25-6)30-20(15)28-14(17)2/h9-12H,7-8H2,1-6H3,(H2,26,29,31)(H,25,27,2show more
    Synonyms
    1454682-72-4 | C72761 | Pan-raf inhibitor ly3009120 | SCHEMBL15241297 | 1-(3,3-dimethylbutyl)-3-[2-fluoro-4-methyl-5-...
  6. 3β-Hydroxy-Δ5-cholenic Acid
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    3β-Hydroxy-Δ5-cholenic Acid
    CAS: 5255-17-4 EC Number: 973-563-1 Formula: C24H38O3 Molecular Weight: 374.57
    ≥97%
    In Stock Item #: H163032
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    Technical Identifiers
    IUPAC Name
    (4R)-4-[(3S,8S,9S,10R,13R,14S,17R)-3-hydroxy-10,13-dimethyl-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-17-yl]pentanoic acid
    SMILES
    CC(CCC(=O)O)C1CCC2C1(CCC3C2CC=C4C3(CCC(C4)O)C)C
    InChIKey
    HIAJCGFYHIANNA-QIZZZRFXSA-N
    InChI
    1S/C24H38O3/c1-15(4-9-22(26)27)19-7-8-20-18-6-5-16-14-17(25)10-12-23(16,2)21(18)11-13-24(19,20)3/h5,15,17-21,25H,4,6-14H2,1-3H3,(H,26,27)/t15-,17+,18+show more
    Synonyms
    3beta-Hydroxy-5-cholenoate | Chol-5-en-24-oic acid, 3-hydroxy-, (3b)- | 3b-hydroxy-5-cholenoic acid | 3.beta.-Hydroxy...
  7. 3β-Hydroxy-Δ5-cholenic Acid
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    3β-Hydroxy-Δ5-cholenic Acid
    CAS: 5255-17-4 EC Number: 973-563-1 Formula: C24H38O3 Molecular Weight: 374.57
    10mM in DMSO
    In Stock Item #: H424508
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    Technical Identifiers
    IUPAC Name
    (4R)-4-[(3S,8S,9S,10R,13R,14S,17R)-3-hydroxy-10,13-dimethyl-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-17-yl]pentanoic acid
    SMILES
    CC(CCC(=O)O)C1CCC2C1(CCC3C2CC=C4C3(CCC(C4)O)C)C
    InChIKey
    HIAJCGFYHIANNA-QIZZZRFXSA-N
    InChI
    1S/C24H38O3/c1-15(4-9-22(26)27)19-7-8-20-18-6-5-16-14-17(25)10-12-23(16,2)21(18)11-13-24(19,20)3/h5,15,17-21,25H,4,6-14H2,1-3H3,(H,26,27)/t15-,17+,18+show more
    Synonyms
    3beta-Hydroxy-5-cholenoate | Chol-5-en-24-oic acid, 3-hydroxy-, (3b)- | 3b-hydroxy-5-cholenoic acid | 3.beta.-Hydroxy...
  8. ALW-II-41-27
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    ALW-II-41-27
    CAS: 1186206-79-0 Formula: C32H32F3N5O2S Molecular Weight: 607.69
    10mM in DMSO
    In Stock Item #: A420821
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    Technical Identifiers
    IUPAC Name
    N-[5-[[4-[(4-ethylpiperazin-1-yl)methyl]-3-(trifluoromethyl)phenyl]carbamoyl]-2-methylphenyl]-5-thiophen-2-ylpyridine-3-carboxamide
    SMILES
    CCN1CCN(CC1)CC2=C(C=C(C=C2)NC(=O)C3=CC(=C(C=C3)C)NC(=O)C4=CN=CC(=C4)C5=CC=CS5)C(F)(F)F
    InChIKey
    HYWXBDQAYLPMIX-UHFFFAOYSA-N
    InChI
    1S/C32H32F3N5O2S/c1-3-39-10-12-40(13-11-39)20-23-8-9-26(17-27(23)32(33,34)35)37-30(41)22-7-6-21(2)28(16-22)38-31(42)25-15-24(18-36-19-25)29-5-4-14-43-show more
    Synonyms
    ALW-II-41-27|1186206-79-0|N-(5-((4-((4-ethylpiperazin-1-yl)methyl)-3-(trifluoromethyl)phenyl)carbamoyl)-2-methylpheny...
  9. Alisertib (MLN8237), Serine/threonine-protein kinase Aurora-A inhibitor
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    Alisertib (MLN8237), Serine/threonine-protein kinase Aurora-A inhibitor
    CAS: 1028486-01-2 Formula: C27H20ClFN4O4 Molecular Weight: 518.94
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. 10mM in DMSO
    In Stock Item #: A408546
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    Technical Identifiers
    Synonyms
    Benzoic acid, 4-[[9-chloro-7-(2-fluoro-6-methoxyphenyl)-5H-pyrimido[5,4-d][2]benzazepin-2-yl]amino]-2-methoxy-
  10. Dorsomorphin, Inhibitor of EPH receptor A2;Inhibitor of fms related receptor tyrosine kinase 1;Inhibitor of fms related receptor tyrosine kinase 3;Inhibitor of kinase insert domain receptor;Inhibitor of LCK proto-oncogene; Src family tyrosine kinase;Inhibitor of MAPK i
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    Dorsomorphin, Inhibitor of EPH receptor A2;Inhibitor of fms related receptor tyrosine kinase 1;Inhibitor of fms related receptor tyrosine kinase 3;Inhibitor of kinase insert domain receptor;Inhibitor of LCK proto-oncogene; Src family tyrosine kinase;Inhibitor of MAPK i
    CAS: 866405-64-3 EC Number: 635-949-5 Formula: C24H25N5O Molecular Weight: 399.49
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. 2mM in DMSO
    In Stock Item #: D426448
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    Technical Identifiers
    IUPAC Name
    6-[4-(2-piperidin-1-ylethoxy)phenyl]-3-pyridin-4-ylpyrazolo[1,5-a]pyrimidine
    SMILES
    C1CCN(CC1)CCOC2=CC=C(C=C2)C3=CN4C(=C(C=N4)C5=CC=NC=C5)N=C3
    InChIKey
    XHBVYDAKJHETMP-UHFFFAOYSA-N
    InChI
    1S/C24H25N5O/c1-2-12-28(13-3-1)14-15-30-22-6-4-19(5-7-22)21-16-26-24-23(17-27-29(24)18-21)20-8-10-25-11-9-20/h4-11,16-18H,1-3,12-15H2
    Synonyms
    BML-275 | 6-[4-(2-piperidin-1-ylethoxy)phenyl]-3-pyridin-4-yl-pyrazolo[1,5-a]pyrimidine | AC-27419 | SY256013 | AM200...
  11. LY 3009120, Inhibitor of A-Raf proto-oncogene; serine/threonine kinase;Inhibitor of B-Raf proto-oncogene; serine/threonine kinase;Inhibitor of Raf-1 proto-oncogene; serine/threonine kinase
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    LY 3009120, Inhibitor of A-Raf proto-oncogene; serine/threonine kinase;Inhibitor of B-Raf proto-oncogene; serine/threonine kinase;Inhibitor of Raf-1 proto-oncogene; serine/threonine kinase
    CAS: 1454682-72-4 Formula: C23H29FN6O Molecular Weight: 424.52
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. 2mM in DMSO
    In Stock Item #: L421677
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    Technical Identifiers
    IUPAC Name
    1-(3,3-dimethylbutyl)-3-[2-fluoro-4-methyl-5-[7-methyl-2-(methylamino)pyrido[2,3-d]pyrimidin-6-yl]phenyl]urea
    SMILES
    CC1=CC(=C(C=C1C2=C(N=C3C(=C2)C=NC(=N3)NC)C)NC(=O)NCCC(C)(C)C)F
    InChIKey
    HHCBMISMPSAZBF-UHFFFAOYSA-N
    InChI
    1S/C23H29FN6O/c1-13-9-18(24)19(29-22(31)26-8-7-23(3,4)5)11-16(13)17-10-15-12-27-21(25-6)30-20(15)28-14(17)2/h9-12H,7-8H2,1-6H3,(H2,26,29,31)(H,25,27,2show more
    Synonyms
    LY3009120|1454682-72-4|LY-3009120|DP-4978|1-(3,3-dimethylbutyl)-3-[2-fluoro-4-methyl-5-[7-methyl-2-(methylamino)pyrid...
  12. no_selection
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    (2S)-2-[[(4R)-4-[(3R,5R,8R,9S,10S,13R,14S,17R)-3-hydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]pentanoyl]amino]-3-(1H-indol-3-yl)propanoic acid, Inhibitor of EPH receptor A1;Inhibitor of EPH receptor A2;Inhibitor of EPH receptor A3;Inhibitor of EPH receptor A4;Inhibitor of EPH receptor A5;Inhibitor of EPH receptor A6;Inhibitor of EPH receptor A7;Inhibitor of EPH receptor A8;Inhibitor of EPH recept
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools.
    Out of Stock Item #: S608920
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    Technical Identifiers
    IUPAC Name
    (2S)-2-[[(4R)-4-[(3R,5R,8R,9S,10S,13R,14S,17R)-3-hydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-1show more
    SMILES
    O[C@@H]1CC[C@]2([C@@H](C1)CC[C@@H]1[C@@H]2CC[C@]2([C@H]1CC[C@@H]2[C@@H](CCC(=O)N[C@H](C(=O)O)Cc1c[nH]c2c1cccc2)C)C)C
    InChIKey
    ITOFPJRDSCGOSA-KZLRUDJFSA-N
    InChI
    1S/C35H50N2O4/c1-21(8-13-32(39)37-31(33(40)41)18-22-20-36-30-7-5-4-6-25(22)30)27-11-12-28-26-10-9-23-19-24(38)14-16-34(23,2)29(26)15-17-35(27,28)3/h4-show more
    Synonyms
    PCM126 | compound 20
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