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Map/microtubule affinity-regulating kinase 4 (MARK4)

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  1. PF-03814735
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    PF-03814735
    CAS: 942487-16-3 Formula: C23H25F3N6O2 Molecular Weight: 474.48
    ≥98%
    Out of Stock Item #: P127543
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    Technical Identifiers
    IUPAC Name
    N-[2-[(1R,8S)-4-[[4-(cyclobutylamino)-5-(trifluoromethyl)pyrimidin-2-yl]amino]-11-azatricyclo[6.2.1.02,7]undeca-2(7),3,5-trien-11-yl]-2-oxoethyl]acetashow more
    SMILES
    CC(=O)NCC(=O)N1C2CCC1C3=C2C=CC(=C3)NC4=NC=C(C(=N4)NC5CCC5)C(F)(F)F
    InChIKey
    RYYNGWLOYLRZLK-RBUKOAKNSA-N
    InChI
    1S/C23H25F3N6O2/c1-12(33)27-11-20(34)32-18-7-8-19(32)16-9-14(5-6-15(16)18)30-22-28-10-17(23(24,25)26)21(31-22)29-13-3-2-4-13/h5-6,9-10,13,18-19H,2-4,7show more
    Synonyms
    UNII-6V5T4O5758 | NSC801015 | NSC-801015 | DTXSID601025621 | C23H25F3N6O2 | Q27265567 | PF03814735 | PF-03814735 | s2...
  2. BX-912, Inhibitor of 3-phosphoinositide dependent protein kinase 1;Inhibitor of checkpoint kinase 1;Inhibitor of cyclin dependent kinase 2;Inhibitor of glycogen synthase kinase 3 beta;Inhibitor of kinase insert domain receptor;Inhibitor of protein kinase A
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    BX-912, Inhibitor of 3-phosphoinositide dependent protein kinase 1;Inhibitor of checkpoint kinase 1;Inhibitor of cyclin dependent kinase 2;Inhibitor of glycogen synthase kinase 3 beta;Inhibitor of kinase insert domain receptor;Inhibitor of protein kinase A
    CAS: 702674-56-4 EC Number: 809-821-6 Formula: C20H23BrN8O Molecular Weight: 471.36
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥97%
    In Stock Item #: B126138
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    IUPAC Name
    N-[3-[[5-bromo-4-[2-(1H-imidazol-5-yl)ethylamino]pyrimidin-2-yl]amino]phenyl]pyrrolidine-1-carboxamide
    SMILES
    C1CCN(C1)C(=O)NC2=CC=CC(=C2)NC3=NC=C(C(=N3)NCCC4=CN=CN4)Br
    InChIKey
    DMMILYKXNCVKOJ-UHFFFAOYSA-N
    InChI
    1S/C20H23BrN8O/c21-17-12-24-19(28-18(17)23-7-6-16-11-22-13-25-16)26-14-4-3-5-15(10-14)27-20(30)29-8-1-2-9-29/h3-5,10-13H,1-2,6-9H2,(H,22,25)(H,27,30)(show more
    Synonyms
    HY-11005 | N-(3-((4-((2-(1H-imidazol-4-yl)ethyl)amino)-5-bromopyrimidin-2-yl)amino)phenyl)pyrrolidine-1-carboxamide;B...
  3. Rivastigmine Tartrate, Cholinesterases; ACHE & BCHE inhibitor
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    Rivastigmine Tartrate, Cholinesterases; ACHE & BCHE inhibitor
    CAS: 129101-54-8 EC Number: 603-318-3 PubChem CID: 6918078 Formula: C14H22N2O2 · C4H6O6 Molecular Weight: 400.42
    ≥98%
    In Stock Item #: R129987
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    IUPAC Name
    (2R,3R)-2,3-dihydroxybutanedioic acid;[3-[(1S)-1-(dimethylamino)ethyl]phenyl] N-ethyl-N-methylcarbamate
    SMILES
    CCN(C)C(=O)OC1=CC=CC(=C1)C(C)N(C)C.C(C(C(=O)O)O)(C(=O)O)O
    InChIKey
    GWHQHAUAXRMMOT-MBANBULQSA-N
    InChI
    1S/C14H22N2O2.C4H6O6/c1-6-16(5)14(17)18-13-9-7-8-12(10-13)11(2)15(3)4;5-1(3(7)8)2(6)4(9)10/h7-11H,6H2,1-5H3;1-2,5-6H,(H,7,8)(H,9,10)/t11-;1-,2-/m01/s1
    Synonyms
    Q27133236 | AKOS022179413 | AS-14385 | AKOS003617905 | Carbamic acid, ethylmethyl-, 3-(1-(dimethylamino)ethyl)phenyl ...
  5. Rivastigmine Tartrate, Cholinesterases; ACHE & BCHE inhibitor
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    Rivastigmine Tartrate, Cholinesterases; ACHE & BCHE inhibitor
    CAS: 129101-54-8 EC Number: 603-318-3 PubChem CID: 6918078 Formula: C14H22N2O2 · C4H6O6 Molecular Weight: 400.42
    10mM in DMSO
    Out of Stock Item #: R408641
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    Synonyms
    ENA 713 | N-​ethyl-​N-​methyl-​carbamic acid 3-​[(1S)​-​1-​(dimethylamino)​ethyl]​phenyl ester, (2R,​3R)​-​2,​3-​dihy...
  6. α-Mangostin
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    α-Mangostin
    CAS: 6147-11-1 EC Number: 683-120-1 Formula: C24H26O6 Molecular Weight: 410.46
    10mM in DMSO
    In Stock Item #: M425091
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    IUPAC Name
    1,3,6-trihydroxy-7-methoxy-2,8-bis(3-methylbut-2-enyl)xanthen-9-one
    SMILES
    CC(=CCC1=C(C2=C(C=C1O)OC3=C(C2=O)C(=C(C(=C3)O)OC)CC=C(C)C)O)C
    InChIKey
    GNRIZKKCNOBBMO-UHFFFAOYSA-N
    InChI
    1S/C24H26O6/c1-12(2)6-8-14-16(25)10-19-21(22(14)27)23(28)20-15(9-7-13(3)4)24(29-5)17(26)11-18(20)30-19/h6-7,10-11,25-27H,8-9H2,1-5H3
    Synonyms
    1,3,6-trihydroxy-7-methoxy-2,8-bis(3-methylbut-2-enyl)-9H-xanthen-9-one | A833244 | NSC 139154 | 9H-Xanthen-9-one,1,3...
  7. α-Mangostin
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    α-Mangostin
    CAS: 6147-11-1 EC Number: 683-120-1 Formula: C24H26O6 Molecular Weight: 410.46
    ≥98%(HPLC)
    In Stock Item #: M101531
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    Technical Identifiers
    IUPAC Name
    1,3,6-trihydroxy-7-methoxy-2,8-bis(3-methylbut-2-enyl)xanthen-9-one
    SMILES
    CC(=CCC1=C(C2=C(C=C1O)OC3=C(C2=O)C(=C(C(=C3)O)OC)CC=C(C)C)O)C
    InChIKey
    GNRIZKKCNOBBMO-UHFFFAOYSA-N
    InChI
    1S/C24H26O6/c1-12(2)6-8-14-16(25)10-19-21(22(14)27)23(28)20-15(9-7-13(3)4)24(29-5)17(26)11-18(20)30-19/h6-7,10-11,25-27H,8-9H2,1-5H3
    Synonyms
    1,3,6-trihydroxy-7-methoxy-2,8-bis(3-methylbut-2-enyl)-9H-xanthen-9-one | A833244 | NSC 139154 | 9H-Xanthen-9-one,1,3...
  8. no_selection
    Wish List Compare
    5-cyclopropyl-4-N-[2-(1H-imidazol-5-yl)ethyl]-2-N-[3-(morpholin-4-ylmethyl)phenyl]pyrimidine-2,4-diamine, Inhibitor of microtubule affinity regulating kinase 3;Inhibitor of microtubule affinity regulating kinase 4
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools.
    Out of Stock Item #: C608731
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    IUPAC Name
    5-cyclopropyl-4-N-[2-(1H-imidazol-5-yl)ethyl]-2-N-[3-(morpholin-4-ylmethyl)phenyl]pyrimidine-2,4-diamine
    SMILES
    C(Cc1c[nH]cn1)Nc1nc(Nc2cccc(CN3CCOCC3)c2)ncc1C1CC1
    InChIKey
    HZHDCONQUBRRDH-UHFFFAOYSA-N
    InChI
    1S/C23H29N7O/c1-2-17(15-30-8-10-31-11-9-30)12-19(3-1)28-23-26-14-21(18-4-5-18)22(29-23)25-7-6-20-13-24-16-27-20/h1-3,12-14,16,18H,4-11,15H2,(H,24,27)(show more
    Synonyms
    compound 14
  9. no_selection
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    N-[3-[[5-bromo-2-[[3-methyl-1-(2,2,2-trifluoroethyl)pyrazol-4-yl]amino]pyrimidin-4-yl]amino]propyl]cyclobutanecarboxamide, Inhibitor of serine/threonine kinase 17a
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools.
    Out of Stock Item #: N609433
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    Technical Identifiers
    IUPAC Name
    N-[3-[[5-bromo-2-[[3-methyl-1-(2,2,2-trifluoroethyl)pyrazol-4-yl]amino]pyrimidin-4-yl]amino]propyl]cyclobutanecarboxamide
    SMILES
    Cc1nn(CC(F)(F)F)cc1Nc1ncc(Br)c(NCCCNC(=O)C2CCC2)n1
    InChIKey
    PJLYZTYJSMPZHT-UHFFFAOYSA-N
    InChI
    1S/C18H23BrF3N7O/c1-11-14(9-29(28-11)10-18(20,21)22)26-17-25-8-13(19)15(27-17)23-6-3-7-24-16(30)12-4-2-5-12/h8-9,12H,2-7,10H2,1H3,(H,24,30)(H2,23,25,2show more
    Synonyms
    compound 7
  11. MRT199665
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    MRT199665
    CAS: 1456858-57-3 PubChem CID: 71725150 Formula: C28H31N5O2 Molecular Weight: 469.58
    ≥99%
    Out of Stock Item #: M646396
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    Technical Identifiers
    IUPAC Name
    7-[(1S)-4-hydroxy-2,3-dihydro-1H-inden-1-yl]-5,5-dimethyl-2-[3-(pyrrolidin-1-ylmethyl)anilino]pyrrolo[2,3-d]pyrimidin-6-one
    SMILES
    CC1(C2=CN=C(N=C2N(C1=O)C3CCC4=C3C=CC=C4O)NC5=CC=CC(=C5)CN6CCCC6)C
    InChIKey
    OFIFLUFVENTCNZ-QHCPKHFHSA-N
    InChI
    1S/C28H31N5O2/c1-28(2)22-16-29-27(30-19-8-5-7-18(15-19)17-32-13-3-4-14-32)31-25(22)33(26(28)35)23-12-11-21-20(23)9-6-10-24(21)34/h5-10,15-16,23,34H,3-show more
  12. PF-03814735
    Wish List Compare
    PF-03814735
    CAS: 942487-16-3 Formula: C23H25F3N6O2 Molecular Weight: 474.48
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. 10 mM in DMSO
    Out of Stock Item #: P1497210
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