Mitogen-activated protein kinase kinase kinase 8 (MAP3K8)

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  1. MEK Inhibitor II, Inhibitor of mitogen-activated protein kinase kinase 1;Inhibitor of mitogen-activated protein kinase kinase kinase 8
    CAS: 623163-52-0 Formula: C14H8NO4Cl Molecular Weight: 289.7
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    In Stock Item #: M333585
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    IUPAC Name
    1-(3-chloro-1,4-dioxonaphthalen-2-yl)pyrrolidine-2,5-dione
    SMILES
    C1CC(=O)N(C1=O)C2=C(C(=O)C3=CC=CC=C3C2=O)Cl
    InChIKey
    GYQSWJNGTWVFOL-UHFFFAOYSA-N
    InChI
    1S/C14H8ClNO4/c15-11-12(16-9(17)5-6-10(16)18)14(20)8-4-2-1-3-7(8)13(11)19/h1-4H,5-6H2
    Synonyms
    NCI60_031219 | 1-(3-chloro-1,4-dioxonaphthalen-2-yl)pyrrolidine-2,5-dione | GTPL6007 | NSC686549 | NSC-686549 | MEK I...
  2. TC-S 7006, Inhibitor of mitogen-activated protein kinase kinase kinase 8
    CAS: 871307-18-5 EC Number: 111-094-9 PubChem CID: 9549300 Formula: C21H14ClFN6 Molecular Weight: 404.83
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥99%
    Out of Stock Item #: T287927
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    IUPAC Name
    4-(3-chloro-4-fluoroanilino)-6-(pyridin-3-ylmethylamino)-1,7-naphthyridine-3-carbonitrile
    SMILES
    C1=CC(=CN=C1)CNC2=NC=C3C(=C2)C(=C(C=N3)C#N)NC4=CC(=C(C=C4)F)Cl
    InChIKey
    NMEUKWOOQOHUNA-UHFFFAOYSA-N
    InChI
    1S/C21H14ClFN6/c22-17-6-15(3-4-18(17)23)29-21-14(8-24)11-26-19-12-28-20(7-16(19)21)27-10-13-2-1-5-25-9-13/h1-7,9,11-12H,10H2,(H,26,29)(H,27,28)
    Synonyms
    DTXSID20946032 | 4-(3-chloro-4-fluorophenylamino)-6-(pyridin-3-ylmethylamino)-1,7-naphthyridine-3-carbonitrile | 4-(3...
  3. Cot inhibitor-2
    CAS: 915363-56-3 PubChem CID: 44143370 Formula: C26H25Cl2FN8 Molecular Weight: 539.43
    Out of Stock Item #: C650545
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    IUPAC Name
    8-chloro-4-(3-chloro-4-fluoroanilino)-6-[[1-(1-ethylpiperidin-4-yl)triazol-4-yl]methylamino]quinoline-3-carbonitrile
    SMILES
    CCN1CCC(CC1)N2C=C(N=N2)CNC3=CC4=C(C(=CN=C4C(=C3)Cl)C#N)NC5=CC(=C(C=C5)F)Cl
    InChIKey
    PHNZIIMWDVXPGG-UHFFFAOYSA-N
    InChI
    1S/C26H25Cl2FN8/c1-2-36-7-5-20(6-8-36)37-15-19(34-35-37)14-31-18-9-21-25(33-17-3-4-24(29)22(27)10-17)16(12-30)13-32-26(21)23(28)11-18/h3-4,9-11,13,15,show more
    Synonyms
    BDBM29923 | 8-chloro-4-(3-chloro-4-fluoroanilino)-6-[[1-(1-ethylpiperidin-4-yl)triazol-4-yl]methylamino]quinoline-3-c...
  4. Tpl2 Kinase Inhibitor 1
    CAS: 871307-18-5 EC Number: 111-094-9 PubChem CID: 9549300 Formula: C21H14ClFN6 Molecular Weight: 404.83
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. 10 mM in DMSO
    Out of Stock Item #: T1495533
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