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Serine/threonine-protein kinase 16 (STK16)

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  1. R406 (free base), Tyrosine-protein kinase SYK inhibitor
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    R406 (free base), Tyrosine-protein kinase SYK inhibitor
    CAS: 841290-80-0 EC Number: 617-533-5 PubChem CID: 11213558 Formula: C22H23FN6O5 Molecular Weight: 470.45
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥99%
    In Stock Item #: R129910
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    IUPAC Name
    6-[[5-fluoro-2-(3,4,5-trimethoxyanilino)pyrimidin-4-yl]amino]-2,2-dimethyl-4H-pyrido[3,2-b][1,4]oxazin-3-one
    SMILES
    CC1(C(=O)NC2=C(O1)C=CC(=N2)NC3=NC(=NC=C3F)NC4=CC(=C(C(=C4)OC)OC)OC)C
    InChIKey
    NHHQJBCNYHBUSI-UHFFFAOYSA-N
    InChI
    1S/C22H23FN6O5/c1-22(2)20(30)28-19-13(34-22)6-7-16(27-19)26-18-12(23)10-24-21(29-18)25-11-8-14(31-3)17(33-5)15(9-11)32-4/h6-10H,1-5H3,(H3,24,25,26,27,show more
    Synonyms
    HY-11108 | 2H-PYRIDO[3,2-B]-1,4-OXAZIN-3(4H)-ONE,6-[[5-FLUORO-2-[(3,4,5-TRIMETHOXPHENYL)AMINO]-4-PYRIMIDINYL]AMINO]-2...
  2. SGC AAK1 1
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    SGC AAK1 1
    CAS: 2247894-32-0 PubChem CID: 134812845 Formula: C21H25N5O3S Molecular Weight: 427.52
    ≥98%(HPLC)
    In Stock Item #: S288249
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    IUPAC Name
    N-[6-[3-(diethylsulfamoylamino)phenyl]-1H-indazol-3-yl]cyclopropanecarboxamide
    SMILES
    CCN(CC)S(=O)(=O)NC1=CC=CC(=C1)C2=CC3=C(C=C2)C(=NN3)NC(=O)C4CC4
    InChIKey
    UCBIQZUJJSVQHL-UHFFFAOYSA-N
    InChI
    1S/C21H25N5O3S/c1-3-26(4-2)30(28,29)25-17-7-5-6-15(12-17)16-10-11-18-19(13-16)23-24-20(18)22-21(27)14-8-9-14/h5-7,10-14,25H,3-4,8-9H2,1-2H3,(H2,22,23,show more
    Synonyms
    N-(6-(3-((N,N-diethylsulfamoyl)amino)phenyl)-1H-indazol-3-yl)cyclopropanecarboxamide
  3. Fedratinib (SAR302503, TG101348), Tyrosine-protein kinase JAK2 inhibitor
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    Fedratinib (SAR302503, TG101348), Tyrosine-protein kinase JAK2 inhibitor
    CAS: 936091-26-8 EC Number: 829-304-9 PubChem CID: 16722836 Formula: C27H36N6O3S Molecular Weight: 524.68
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    In Stock Item #: T126330
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    IUPAC Name
    N-tert-butyl-3-[[5-methyl-2-[4-(2-pyrrolidin-1-ylethoxy)anilino]pyrimidin-4-yl]amino]benzenesulfonamide
    SMILES
    CC1=CN=C(N=C1NC2=CC(=CC=C2)S(=O)(=O)NC(C)(C)C)NC3=CC=C(C=C3)OCCN4CCCC4
    InChIKey
    JOOXLOJCABQBSG-UHFFFAOYSA-N
    InChI
    1S/C27H36N6O3S/c1-20-19-28-26(30-21-10-12-23(13-11-21)36-17-16-33-14-5-6-15-33)31-25(20)29-22-8-7-9-24(18-22)37(34,35)32-27(2,3)4/h7-13,18-19,32H,5-6,show more
    Synonyms
    7.ALPHA.-METHYLNORETHINDRONE | FEDRATINIB [WHO-DD] | NSC800099 | NSC-800099 | N-Tert-butyl-3-(5-methyl-2-(4-(2-pyrrol...
  4. AKK1-IN-1
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    AKK1-IN-1
    CAS: 1093222-27-5 Formula: C20H13N5O Molecular Weight: 339.35
    Solid Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    In Stock Item #: A412377
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    IUPAC Name
    N-[5-(4-cyanophenyl)-1H-pyrrolo[2,3-b]pyridin-3-yl]pyridine-3-carboxamide
    SMILES
    C1=CC(=CN=C1)C(=O)NC2=CNC3=C2C=C(C=N3)C4=CC=C(C=C4)C#N
    InChIKey
    JTSLALYXYSRPGW-UHFFFAOYSA-N
    InChI
    1S/C20H13N5O/c21-9-13-3-5-14(6-4-13)16-8-17-18(12-24-19(17)23-11-16)25-20(26)15-2-1-7-22-10-15/h1-8,10-12H,(H,23,24)(H,25,26)
    Synonyms
    LKB1/AAK1 dual inhibitor; MDK-2275; MDK 2275; MDK2275 | A927453 | Pim1/AKK1-IN-1 | Q27462573 | F83701 | N-[5-(4-cyano...
  5. Fedratinib (TG101348), Tyrosine-protein kinase JAK2 inhibitor
    Wish List Compare
    Fedratinib (TG101348), Tyrosine-protein kinase JAK2 inhibitor
    CAS: 936091-26-8 EC Number: 829-304-9 PubChem CID: 16722836 Formula: C27H36N6O3S Molecular Weight: 524.68
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. 10mM in DMSO
    In Stock Item #: F408078
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    Synonyms
    SAR302503 | N-tert-butyl-3-(5-methyl-2-(4-(2-(pyrrolidin-1-yl)ethoxy)phenylamino)pyrimidin-4-ylamino)benzenesulfonamide
  6. R406 (free base), Tyrosine-protein kinase SYK inhibitor
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    R406 (free base), Tyrosine-protein kinase SYK inhibitor
    CAS: 841290-80-0 EC Number: 617-533-5 PubChem CID: 11213558 Formula: C22H23FN6O5 Molecular Weight: 470.45
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. 10mM in DMSO
    Out of Stock Item #: R426186
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    Technical Identifiers
    IUPAC Name
    6-[[5-fluoro-2-(3,4,5-trimethoxyanilino)pyrimidin-4-yl]amino]-2,2-dimethyl-4H-pyrido[3,2-b][1,4]oxazin-3-one
    SMILES
    CC1(C(=O)NC2=C(O1)C=CC(=N2)NC3=NC(=NC=C3F)NC4=CC(=C(C(=C4)OC)OC)OC)C
    InChIKey
    NHHQJBCNYHBUSI-UHFFFAOYSA-N
    InChI
    1S/C22H23FN6O5/c1-22(2)20(30)28-19-13(34-22)6-7-16(27-19)26-18-12(23)10-24-21(29-18)25-11-8-14(31-3)17(33-5)15(9-11)32-4/h6-10H,1-5H3,(H3,24,25,26,27,show more
    Synonyms
    HY-11108 | 2H-PYRIDO[3,2-B]-1,4-OXAZIN-3(4H)-ONE,6-[[5-FLUORO-2-[(3,4,5-TRIMETHOXPHENYL)AMINO]-4-PYRIMIDINYL]AMINO]-2...
  7. no_selection
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    N-[3-[[5-bromo-4-[(4-sulfamoylphenyl)methylamino]pyrimidin-2-yl]amino]phenyl]pyrrolidine-1-carboxamide, Inhibitor of AP2 associated kinase 1;Inhibitor of BMP2 inducible kinase;Inhibitor of serine/threonine kinase 16;Inhibitor of tyrosine kinase 2
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools.
    Out of Stock Item #: N608711
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    Technical Identifiers
    IUPAC Name
    N-[3-[[5-bromo-4-[(4-sulfamoylphenyl)methylamino]pyrimidin-2-yl]amino]phenyl]pyrrolidine-1-carboxamide
    SMILES
    NS(=O)(=O)c1ccc(CNc2nc(Nc3cccc(NC(=O)N4CCCC4)c3)ncc2Br)cc1
    InChIKey
    OEZHSZIDGUKBRK-UHFFFAOYSA-N
    InChI
    1S/C22H24BrN7O3S/c23-19-14-26-21(29-20(19)25-13-15-6-8-18(9-7-15)34(24,32)33)27-16-4-3-5-17(12-16)28-22(31)30-10-1-2-11-30/h3-9,12,14H,1-2,10-11,13H2,show more
    Synonyms
    compound 13
  8. no_selection
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    4-[[[5-bromo-2-[3-(morpholin-4-ylmethyl)anilino]pyrimidin-4-yl]amino]methyl]benzenesulfonamide, Inhibitor of AP2 associated kinase 1;Inhibitor of BMP2 inducible kinase;Inhibitor of serine/threonine kinase 16;Inhibitor of TANK binding kinase 1;Inhibitor of tyrosine kinase 2
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools.
    Out of Stock Item #: B609392
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    Technical Identifiers
    IUPAC Name
    4-[[[5-bromo-2-[3-(morpholin-4-ylmethyl)anilino]pyrimidin-4-yl]amino]methyl]benzenesulfonamide
    SMILES
    NS(=O)(=O)c1ccc(CNc2nc(Nc3cccc(CN4CCOCC4)c3)ncc2Br)cc1
    InChIKey
    RDROKTFULACVDQ-UHFFFAOYSA-N
    InChI
    1S/C22H25BrN6O3S/c23-20-14-26-22(27-18-3-1-2-17(12-18)15-29-8-10-32-11-9-29)28-21(20)25-13-16-4-6-19(7-5-16)33(24,30)31/h1-7,12,14H,8-11,13,15H2,(H2,2show more
    Synonyms
    compound 6
  9. Pim1/AKK1-IN-1
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    Pim1/AKK1-IN-1
    CAS: 1093222-27-5 Formula: C20H13N5O Molecular Weight: 339.35
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. 10 mM in DMSO
    Out of Stock Item #: P1493725
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  10. SGC-AAK1-1
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    SGC-AAK1-1
    CAS: 2247894-32-0 PubChem CID: 134812845 Formula: C21H25N5O3S Molecular Weight: 427.52
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. 10 mM in DMSO
    Out of Stock Item #: S1495564
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