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Serine/threonine-protein kinase sik1 (SIK1)

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  1. ARN-3236, Inhibitor of salt inducible kinase 1;Inhibitor of salt inducible kinase 2;Inhibitor of SIK family kinase 3
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    ARN-3236, Inhibitor of salt inducible kinase 1;Inhibitor of salt inducible kinase 2;Inhibitor of SIK family kinase 3
    CAS: 1613710-01-2 Formula: C19H16N2O2S Molecular Weight: 336.41
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. 10mM in DMSO
    In Stock Item #: A421945
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    Technical Identifiers
    IUPAC Name
    3-(2,4-dimethoxyphenyl)-4-thiophen-3-yl-1H-pyrrolo[2,3-b]pyridine
    SMILES
    COC1=CC(=C(C=C1)C2=CNC3=NC=CC(=C23)C4=CSC=C4)OC
    InChIKey
    WEHOIIGXTMKVRG-UHFFFAOYSA-N
    InChI
    1S/C19H16N2O2S/c1-22-13-3-4-15(17(9-13)23-2)16-10-21-19-18(16)14(5-7-20-19)12-6-8-24-11-12/h3-11H,1-2H3,(H,20,21)
    Synonyms
    1H-​Pyrrolo[2,​3-​b]​pyridine,3-​(2,​4-​dimethoxyphenyl)​-​4-​(3-​thienyl)​-
  2. ARN-3236 - Moligand™, ≥98%, CAS No. 1613710-01-2 by
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    ARN-3236, Inhibitor of salt inducible kinase 1;Inhibitor of salt inducible kinase 2;Inhibitor of SIK family kinase 3
    CAS: 1613710-01-2 Formula: C19H16N2O2S Molecular Weight: 336.41
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    In Stock Item #: A414050
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    Technical Identifiers
    IUPAC Name
    3-(2,4-dimethoxyphenyl)-4-thiophen-3-yl-1H-pyrrolo[2,3-b]pyridine
    SMILES
    COC1=CC(=C(C=C1)C2=CNC3=NC=CC(=C23)C4=CSC=C4)OC
    InChIKey
    WEHOIIGXTMKVRG-UHFFFAOYSA-N
    InChI
    1S/C19H16N2O2S/c1-22-13-3-4-15(17(9-13)23-2)16-10-21-19-18(16)14(5-7-20-19)12-6-8-24-11-12/h3-11H,1-2H3,(H,20,21)
    Synonyms
    1H-​Pyrrolo[2,​3-​b]​pyridine,3-​(2,​4-​dimethoxyphenyl)​-​4-​(3-​thienyl)​-
  3. HG-9-91-01, Inhibitor of salt inducible kinase 1;Inhibitor of salt inducible kinase 2;Inhibitor of SIK family kinase 3
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    HG-9-91-01, Inhibitor of salt inducible kinase 1;Inhibitor of salt inducible kinase 2;Inhibitor of SIK family kinase 3
    CAS: 1456858-58-4 Formula: C32H37N7O3 Molecular Weight: 567.68
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. 10mM in DMSO
    In Stock Item #: H421682
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    Technical Identifiers
    IUPAC Name
    1-(2,4-dimethoxyphenyl)-3-(2,6-dimethylphenyl)-1-[6-[4-(4-methylpiperazin-1-yl)anilino]pyrimidin-4-yl]urea
    SMILES
    CC1=C(C(=CC=C1)C)NC(=O)N(C2=C(C=C(C=C2)OC)OC)C3=NC=NC(=C3)NC4=CC=C(C=C4)N5CCN(CC5)C
    InChIKey
    UYUHRKLITDJEHB-UHFFFAOYSA-N
    InChI
    1S/C32H37N7O3/c1-22-7-6-8-23(2)31(22)36-32(40)39(27-14-13-26(41-4)19-28(27)42-5)30-20-29(33-21-34-30)35-24-9-11-25(12-10-24)38-17-15-37(3)16-18-38/h6-show more
    Synonyms
    BCP25041 | DTXSID401025699 | SCHEMBL15271960 | SIK inhibitor 1 | HG-9-91-01 (1) | MS-30272 | 1-(2,4-Dimethoxyphenyl)-...
  4. HG-9-91-01, Inhibitor of salt inducible kinase 1;Inhibitor of salt inducible kinase 2;Inhibitor of SIK family kinase 3
    Wish List Compare
    HG-9-91-01, Inhibitor of salt inducible kinase 1;Inhibitor of salt inducible kinase 2;Inhibitor of SIK family kinase 3
    CAS: 1456858-58-4 Formula: C32H37N7O3 Molecular Weight: 567.68
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥99%
    In Stock Item #: H413999
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    Pricing & Pack Sizes
    Technical Identifiers
    IUPAC Name
    1-(2,4-dimethoxyphenyl)-3-(2,6-dimethylphenyl)-1-[6-[4-(4-methylpiperazin-1-yl)anilino]pyrimidin-4-yl]urea
    SMILES
    CC1=C(C(=CC=C1)C)NC(=O)N(C2=C(C=C(C=C2)OC)OC)C3=NC=NC(=C3)NC4=CC=C(C=C4)N5CCN(CC5)C
    InChIKey
    UYUHRKLITDJEHB-UHFFFAOYSA-N
    InChI
    1S/C32H37N7O3/c1-22-7-6-8-23(2)31(22)36-32(40)39(27-14-13-26(41-4)19-28(27)42-5)30-20-29(33-21-34-30)35-24-9-11-25(12-10-24)38-17-15-37(3)16-18-38/h6-show more
    Synonyms
    BCP25041 | DTXSID401025699 | SCHEMBL15271960 | SIK inhibitor 1 | HG-9-91-01 (1) | MS-30272 | 1-(2,4-Dimethoxyphenyl)-...
  5. YKL-05-099
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    YKL-05-099
    CAS: 1936529-65-5 PubChem CID: 121596782 Formula: C32H34ClN7O3 Molecular Weight: 600.11
    10mM in DMSO
    In Stock Item #: Y422363
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    IUPAC Name
    3-(2-chloro-6-methylphenyl)-7-[2-methoxy-4-(1-methylpiperidin-4-yl)anilino]-1-(5-methoxypyridin-2-yl)-4H-pyrimido[4,5-d]pyrimidin-2-one
    SMILES
    CC1=C(C(=CC=C1)Cl)N2CC3=CN=C(N=C3N(C2=O)C4=NC=C(C=C4)OC)NC5=C(C=C(C=C5)C6CCN(CC6)C)OC
    InChIKey
    VQINULODWGEVBB-UHFFFAOYSA-N
    InChI
    1S/C32H34ClN7O3/c1-20-6-5-7-25(33)29(20)39-19-23-17-35-31(37-30(23)40(32(39)41)28-11-9-24(42-3)18-34-28)36-26-10-8-22(16-27(26)43-4)21-12-14-38(2)15-1show more
    Synonyms
    Pyrimido[4,​5-​d]​pyrimidin-​2(1H)​-​one,3-​(2-​chloro-​6-​methylphenyl)​-​3,​4-​dihydro-​7-​[[2-​methoxy-​4-​(1-​met...
  6. YKL-05-099
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    YKL-05-099
    CAS: 1936529-65-5 PubChem CID: 121596782 Formula: C32H34ClN7O3 Molecular Weight: 600.11
    ≥98%
    In Stock Item #: Y414441
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    Technical Identifiers
    IUPAC Name
    3-(2-chloro-6-methylphenyl)-7-[2-methoxy-4-(1-methylpiperidin-4-yl)anilino]-1-(5-methoxypyridin-2-yl)-4H-pyrimido[4,5-d]pyrimidin-2-one
    SMILES
    CC1=C(C(=CC=C1)Cl)N2CC3=CN=C(N=C3N(C2=O)C4=NC=C(C=C4)OC)NC5=C(C=C(C=C5)C6CCN(CC6)C)OC
    InChIKey
    VQINULODWGEVBB-UHFFFAOYSA-N
    InChI
    1S/C32H34ClN7O3/c1-20-6-5-7-25(33)29(20)39-19-23-17-35-31(37-30(23)40(32(39)41)28-11-9-24(42-3)18-34-28)36-26-10-8-22(16-27(26)43-4)21-12-14-38(2)15-1show more
    Synonyms
    3-(2-chloro-6-methylphenyl)-7-[2-methoxy-4-(1-methylpiperidin-4-yl)anilino]-1-(5-methoxypyridin-2-yl)-4H-pyrimido[4,5...
  7. no_selection
    Wish List Compare
    GLPG3970, Inhibitor of salt inducible kinase 2;Inhibitor of SIK family kinase 3
    CAS: 2403733-82-2 PubChem CID: 146273261
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools.
    Out of Stock Item #: G610582
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    IUPAC Name
    8-methoxy-6-[7-(2-morpholin-4-ylethoxy)imidazo[1,2-a]pyridin-3-yl]-2-(2,2,2-trifluoroethyl)-3,4-dihydroisoquinolin-1-one
    SMILES
    COc1cc(cc2c1C(=O)N(CC2)CC(F)(F)F)c1cnc2n1ccc(c2)OCCN1CCOCC1
    InChIKey
    XASOHFCUIQARJT-UHFFFAOYSA-N
    InChI
    1S/C25H27F3N4O4/c1-34-21-13-18(12-17-2-4-31(16-25(26,27)28)24(33)23(17)21)20-15-29-22-14-19(3-5-32(20)22)36-11-8-30-6-9-35-10-7-30/h3,5,12-15H,2,4,6-1show more
    Synonyms
    GTPL12157 | XASOHFCUIQARJT-UHFFFAOYSA-N | 8-Methoxy-6-[7-(2-morpholin-4-ylethoxy)imidazo[1,2-a]pyridin-3-yl]-2-(2,2,2...
  8. GLPG3970
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    GLPG3970
    CAS: 2403733-82-2 PubChem CID: 146273261
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. 10 mM in DMSO
    Out of Stock Item #: G1497670
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  9. A-216546 free base
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    A-216546 free base
    CAS: 212481-66-8 EC Number: 860-920-0 Formula: C30H48N2O6 Molecular Weight: 532.700
    ≥98%
    Out of Stock Item #: A1007580
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    Technical Identifiers
    IUPAC Name
    (2S,3R,4S)-1-[2-(dibutylamino)-2-oxoethyl]-2-(2,2-dimethylpentyl)-4-(7-methoxy-1,3-benzodioxol-5-yl)pyrrolidine-3-carboxylic acid
    SMILES
    CCCCN(CCCC)C(=O)CN1C[C@@H]([C@H]([C@@H]1CC(C)(C)CCC)C(=O)O)C2=CC3=C(C(=C2)OC)OCO3
    InChIKey
    OAEWNSKRLBVVBV-QSEAXJEQSA-N
    InChI
    1S/C30H48N2O6/c1-7-10-13-31(14-11-8-2)26(33)19-32-18-22(21-15-24(36-6)28-25(16-21)37-20-38-28)27(29(34)35)23(32)17-30(4,5)12-9-3/h15-16,22-23,27H,7-14show more
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