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Proteasome

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  2. Isoginkgetin
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    Isoginkgetin
    CAS: 548-19-6 Formula: C32H22O10 Molecular Weight: 566.51
    ≥98%(HPLC)
    In Stock Item #: I288348
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    Technical Identifiers
    IUPAC Name
    8-[5-(5,7-dihydroxy-4-oxochromen-2-yl)-2-methoxyphenyl]-5,7-dihydroxy-2-(4-methoxyphenyl)chromen-4-one
    SMILES
    COC1=CC=C(C=C1)C2=CC(=O)C3=C(O2)C(=C(C=C3O)O)C4=C(C=CC(=C4)C5=CC(=O)C6=C(C=C(C=C6O5)O)O)OC
    InChIKey
    HUOOMAOYXQFIDQ-UHFFFAOYSA-N
    InChI
    1S/C32H22O10/c1-39-18-6-3-15(4-7-18)26-14-24(38)31-22(36)12-21(35)29(32(31)42-26)19-9-16(5-8-25(19)40-2)27-13-23(37)30-20(34)10-17(33)11-28(30)41-27/hshow more
    Synonyms
    AS-56807 | CHEBI:79087 | KBio2_006022 | HY-N2117 | MFCD00597035 | BRD-K72661036-001-02-1 | KBioSS_000886 | 8-[5-(5,7-...
  3. Gabexate Mesylate
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    Gabexate Mesylate
    CAS: 56974-61-9 Formula: C16H23N3O4·CH4O3S Molecular Weight: 417.48
    Solid ≥99%
    In Stock Item #: G129271
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    Technical Identifiers
    IUPAC Name
    ethyl 4-[6-(diaminomethylideneamino)hexanoyloxy]benzoate;methanesulfonic acid
    SMILES
    CCOC(=O)C1=CC=C(C=C1)OC(=O)CCCCCN=C(N)N.CS(=O)(=O)O
    InChIKey
    DNTNDFLIKUKKOC-UHFFFAOYSA-N
    InChI
    1S/C16H23N3O4.CH4O3S/c1-2-22-15(21)12-7-9-13(10-8-12)23-14(20)6-4-3-5-11-19-16(17)18;1-5(2,3)4/h7-10H,2-6,11H2,1H3,(H4,17,18,19);1H3,(H,2,3,4)
    Synonyms
    HMS3370J02 | ethyl 4-[6-(diaminomethylideneamino)hexanoyloxy]benzoate;methanesulfonic acid | Gabexate mesilate (JP17)...
  4. MG-115
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    MG-115
    CAS: 133407-86-0 Formula: C25H39N3O5 Molecular Weight: 461.59
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥95%
    In Stock Item #: M275487
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    IUPAC Name
    benzyl N-[(2S)-4-methyl-1-[[(2S)-4-methyl-1-oxo-1-[[(2S)-1-oxopentan-2-yl]amino]pentan-2-yl]amino]-1-oxopentan-2-yl]carbamate
    SMILES
    CCCC(C=O)NC(=O)C(CC(C)C)NC(=O)C(CC(C)C)NC(=O)OCC1=CC=CC=C1
    InChIKey
    QEJRGURBLQWEOU-FKBYEOEOSA-N
    InChI
    1S/C25H39N3O5/c1-6-10-20(15-29)26-23(30)21(13-17(2)3)27-24(31)22(14-18(4)5)28-25(32)33-16-19-11-8-7-9-12-19/h7-9,11-12,15,17-18,20-22H,6,10,13-14,16H2show more
    Synonyms
    N-[(2S)-4-methyl-1-[[(2S)-4-methyl-1-oxo-1-[[(2S)-1-oxopentan-2-yl]amino]pentan-2-yl]amino]-1-oxopentan-2-yl]carbamic...
  5. PD 151746
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    PD 151746
    CAS: 179461-52-0 PubChem CID: 5353866 Formula: C11H8FNO2S Molecular Weight: 237.25
    ≥95%
    In Stock Item #: P276048
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    Technical Identifiers
    IUPAC Name
    (Z)-3-(5-fluoro-1H-indol-3-yl)-2-sulfanylprop-2-enoic acid
    SMILES
    C1=CC2=C(C=C1F)C(=CN2)C=C(C(=O)O)S
    InChIKey
    HWMQHECFXSVZGN-KMKOMSMNSA-N
    InChI
    1S/C11H8FNO2S/c12-7-1-2-9-8(4-7)6(5-13-9)3-10(16)11(14)15/h1-5,13,16H,(H,14,15)/b10-3-
    Synonyms
    3-(5-Fluoro-1H-indol-3-yl)-2-mercapto-2-propenoicacid
  6. ONX-0914 (PR-957), Inhibitor of proteasome 20S subunit beta 8
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    ONX-0914 (PR-957), Inhibitor of proteasome 20S subunit beta 8
    CAS: 960374-59-8 Formula: C31H40N4O7 Molecular Weight: 580.67
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    In Stock Item #: O127572
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    Technical Identifiers
    IUPAC Name
    (2S)-3-(4-methoxyphenyl)-N-[(2S)-1-[(2R)-2-methyloxiran-2-yl]-1-oxo-3-phenylpropan-2-yl]-2-[[(2S)-2-[(2-morpholin-4-ylacetyl)amino]propanoyl]amino]proshow more
    SMILES
    CC(C(=O)NC(CC1=CC=C(C=C1)OC)C(=O)NC(CC2=CC=CC=C2)C(=O)C3(CO3)C)NC(=O)CN4CCOCC4
    InChIKey
    WQAVPPWWLLVGFK-VTNASVEKSA-N
    InChI
    1S/C31H40N4O7/c1-21(32-27(36)19-35-13-15-41-16-14-35)29(38)34-26(18-23-9-11-24(40-3)12-10-23)30(39)33-25(28(37)31(2)20-42-31)17-22-7-5-4-6-8-22/h4-12,show more
    Synonyms
    PR-957 | ONX 0914 | ONX0914 | PR957 | PR 957 | N-[2-(4-Morpholinyl)acetyl]-L-alanyl-O-methyl-N-[(1S)-2-[(2R)-2-methyl...
  7. MLN2238, 26S proteasome inhibitor
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    MLN2238, 26S proteasome inhibitor
    CAS: 1072833-77-2 Formula: C14H19BCl2N2O4 Molecular Weight: 361.03
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    In Stock Item #: M128010
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    IUPAC Name
    [(1R)-1-[[2-[(2,5-dichlorobenzoyl)amino]acetyl]amino]-3-methylbutyl]boronic acid
    SMILES
    B(C(CC(C)C)NC(=O)CNC(=O)C1=C(C=CC(=C1)Cl)Cl)(O)O
    InChIKey
    MXAYKZJJDUDWDS-LBPRGKRZSA-N
    InChI
    1S/C14H19BCl2N2O4/c1-8(2)5-12(15(22)23)19-13(20)7-18-14(21)10-6-9(16)3-4-11(10)17/h3-4,6,8,12,22-23H,5,7H2,1-2H3,(H,18,21)(H,19,20)/t12-/m0/s1
    Synonyms
    ENT 25,543 | BCP9000953 | L01XX50 | MFCD18251438 | HY-10453 | BDBM50398609 | Q20948663 | DTXSID701025662 | Ixozamib |...
  8. Oprozomib (ONX 0912), 26S proteosome inhibitor
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    Oprozomib (ONX 0912), 26S proteosome inhibitor
    CAS: 935888-69-0 PubChem CID: 25067547 Formula: C25H32N4O7S Molecular Weight: 532.61
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    In Stock Item #: O129260
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    Technical Identifiers
    IUPAC Name
    N-[(2S)-3-methoxy-1-[[(2S)-3-methoxy-1-[[(2S)-1-[(2R)-2-methyloxiran-2-yl]-1-oxo-3-phenylpropan-2-yl]amino]-1-oxopropan-2-yl]amino]-1-oxopropan-2-yl]-show more
    SMILES
    CC1=NC=C(S1)C(=O)NC(COC)C(=O)NC(COC)C(=O)NC(CC2=CC=CC=C2)C(=O)C3(CO3)C
    InChIKey
    SWZXEVABPLUDIO-WSZYKNRRSA-N
    InChI
    1S/C25H32N4O7S/c1-15-26-11-20(37-15)24(33)29-19(13-35-4)23(32)28-18(12-34-3)22(31)27-17(21(30)25(2)14-36-25)10-16-8-6-5-7-9-16/h5-9,11,17-19H,10,12-14show more
    Synonyms
    ONX-0912 | PR-047 | J-690398 | N-((S)-3-methoxy-1-(((S)-3-methoxy-1-(((S)-1-((R)-2-methyloxiran-2-yl)-1-oxo-3-phenylp...
  9. Calpain Inhibitor VI
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    Calpain Inhibitor VI
    CAS: 190274-53-4 Formula: C17H25FN2O4S Molecular Weight: 372.5
    ≥95%
    Out of Stock Item #: C336446
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    IUPAC Name
    2-[(4-fluorophenyl)sulfonylamino]-3-methyl-N-(4-methyl-1-oxopentan-2-yl)butanamide
    SMILES
    CC(C)CC(C=O)NC(=O)C(C(C)C)NS(=O)(=O)C1=CC=C(C=C1)F
    InChIKey
    WSJWUIDLGZAXID-UHFFFAOYSA-N
    InChI
    1S/C17H25FN2O4S/c1-11(2)9-14(10-21)19-17(22)16(12(3)4)20-25(23,24)15-7-5-13(18)6-8-15/h5-8,10-12,14,16,20H,9H2,1-4H3,(H,19,22)
    Synonyms
    N-(4-Fluorophenylsulfonyl)-L-Valyl-L-Leucinal | 2-[(4-fluorophenyl)sulfonylamino]-3-methyl-N-(4-methyl-1-oxopentan-2-...
  10. Celastrol, Inhibitor of regulator of G-protein signaling 17
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    Celastrol, Inhibitor of regulator of G-protein signaling 17
    CAS: 34157-83-0 EC Number: 636-472-5 Formula: C29H38O4 Molecular Weight: 450.61
    Analytical standard ? Analytical standard — certified-purity material for quantitative calibration. Use to prepare calibration standards and validate analytical methods. Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    In Stock Item #: C107671
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    Technical Identifiers
    IUPAC Name
    (2R,4aS,6aR,6aS,14aS,14bR)-10-hydroxy-2,4a,6a,6a,9,14a-hexamethyl-11-oxo-1,3,4,5,6,13,14,14b-octahydropicene-2-carboxylic acid
    SMILES
    CC1=C(C(=O)C=C2C1=CC=C3C2(CCC4(C3(CCC5(C4CC(CC5)(C)C(=O)O)C)C)C)C)O
    InChIKey
    KQJSQWZMSAGSHN-JJWQIEBTSA-N
    InChI
    1S/C29H38O4/c1-17-18-7-8-21-27(4,19(18)15-20(30)23(17)31)12-14-29(6)22-16-26(3,24(32)33)10-9-25(22,2)11-13-28(21,29)5/h7-8,15,22,31H,9-14,16H2,1-6H3,(show more
    Synonyms
    (2R,4aS,6aR,6aS,14aS,14bR)-10-hydroxy-2,4a,6a,6a,9,14a-hexamethyl-11-oxo-1,3,4,5,6,13,14,14b-octahydropicene-2-carbox...
  11. Calpain Inhibitor XII
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    Calpain Inhibitor XII
    CAS: 181769-57-3 Formula: C26H34N4O5 Molecular Weight: 482.57
    ≥90%
    In Stock Item #: C341237
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    Technical Identifiers
    IUPAC Name
    benzyl N-[1-[[1,2-dioxo-1-(pyridin-2-ylmethylamino)hexan-3-yl]amino]-4-methyl-1-oxopentan-2-yl]carbamate
    SMILES
    CCCC(C(=O)C(=O)NCC1=CC=CC=N1)NC(=O)C(CC(C)C)NC(=O)OCC2=CC=CC=C2
    InChIKey
    PLVWMBFPIAQRHK-UHFFFAOYSA-N
    InChI
    1S/C26H34N4O5/c1-4-10-21(23(31)25(33)28-16-20-13-8-9-14-27-20)29-24(32)22(15-18(2)3)30-26(34)35-17-19-11-6-5-7-12-19/h5-9,11-14,18,21-22H,4,10,15-17H2show more
    Synonyms
    (Rac)-Calpain Inhibitor XII | [3-methyl-1-[[[1-[oxo[(2-pyridinylmethyl)amino]acetyl]butyl]amino]carbonyl]butyl]-carba...
  12. 5-Amino-8-hydroxyquinoline(5A8HQ) - Moligand™,≥96% CAS No(13207-66-4) by Aladdin Scientific
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    5-Amino-8-hydroxyquinoline(5A8HQ)
    CAS: 13207-66-4 EC Number: 108-775-8 Formula: C9H8N2O Molecular Weight: 160.17
    Solid Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥96%
    Out of Stock Item #: A181160
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    Technical Identifiers
    IUPAC Name
    5-aminoquinolin-8-ol
    SMILES
    C1=CC2=C(C=CC(=C2N=C1)O)N
    InChIKey
    YDEUKNRKEYICTH-UHFFFAOYSA-N
    InChI
    1S/C9H8N2O/c10-7-3-4-8(12)9-6(7)2-1-5-11-9/h1-5,12H,10H2
    Synonyms
    N-tert-Butyldimethylsilyl-N-methyltrifluoroacetamide, >=97.0% (GC) | SY045850 | 5-Aminooxin | BB 0221209 | 5-Amino-8-...
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