Maleimidoacetic acid N-hydroxysuccinimide ester - ≥95% , CAS No.55750-61-3

CAS: 55750-61-3 Cat. No.: M170978 Molecular Weight: 252.18 EC Number: 637-252-1

GRADE & PURITY ≥95%

Synonyms

1H-Pyrrole-1-acetic acid, 2,5-dihydro-2,5-dioxo-, 2,5-dioxo-1-pyrrolidinyl ester | GS-5668 | Maleimidoacetic acid N-hydroxysuccinimide ester | AMY21437 | Maleimidoacetic Acid N-Succinimidyl Ester | N-SMP | 1-{2-[(2,5-Dioxopyrrolidin-1-yl)oxy]-2-oxoethyl}-

Storage

Store at -20°C,Argon charged

Shipped In

Ice chest + Ice pads

Application

227,228,229

Specifications

Synonyms

1H-Pyrrole-1-acetic acid, 2, 5-dihydro-2, 5-dioxo-, 2, 5-dioxo-1-pyrrolidinyl ester | GS-5668 | Maleimidoacetic acid N-hydroxysuccinimide ester | AMY21437 | Maleimidoacetic Acid N-Succinimidyl Ester | N-SMP | 1-{2-[(2, 5-Dioxopyrrolidin-1-yl)oxy]-2-oxoethyl}-

Specifications & Purity

≥95%

Storage

Store at -20°C, Argon charged

Shipped In

Ice chest + Ice pads

This product requires cold chain shipping. Ground and other economy services are not available.

Purity

≥95%

Names and Identifiers

• Pubchem Sid: 504762531
• Pubchem Sid Url: https://pubchem.ncbi.nlm.nih.gov/substance/504762531
• Canonical Smiles: C1CC(=O)N(C1=O)OC(=O)CN2C(=O)C=CC2=O
• IUPAC Name: (2,5-dioxopyrrolidin-1-yl) 2-(2,5-dioxopyrrol-1-yl)acetate
• InChIKey: TYKASZBHFXBROF-UHFFFAOYSA-N
• INCHI: 1S/C10H8N2O6/c13-6-1-2-7(14)11(6)5-10(17)18-12-8(15)3-4-9(12)16/h1-2H,3-5H2
• Isomeric SMILES: C1CC(=O)N(C1=O)OC(=O)CN2C(=O)C=CC2=O
• Molecular Weight: 252.18
• Reaxy-Rn: 1492656
• Reaxys-RN_link_address: https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=1492656&ln=

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Organic acids and derivatives
    • Class Carboxylic acids and derivatives
      • Subclass Amino acids, peptides, and analogues
        • Level5 Amino acids and derivatives
          • Level6 Alpha amino acids and derivatives

• Kingdom: Organic compounds
• Superclass: Organic acids and derivatives
• Class: Carboxylic acids and derivatives
• Subclass: Amino acids, peptides, and analogues
• Intermediate Tree Nodes: Amino acids and derivatives
• Direct Parent: Alpha amino acids and derivatives
• Alternative Parents: Maleimides Pyrrolidine-2-ones N-substituted carboxylic acid imides Pyrrolines Dicarboximides Lactams Monocarboxylic acids and derivatives Azacyclic compounds Organonitrogen compounds Organic oxides Hydrocarbon derivatives Carbonyl compounds
• Molecular Framework: Aliphatic heteromonocyclic compounds
• Substituents: Alpha-amino acid or derivatives - Maleimide - Carboxylic acid imide, n-substituted - Pyrrolidone - 2-pyrrolidone - Carboxylic acid imide - Dicarboximide - Pyrrolidine - Pyrroline - Lactam - Azacycle - Monocarboxylic acid or derivatives - Organoheterocyclic compound - Organooxygen compound - Organonitrogen compound - Hydrocarbon derivative - Organic oxide - Organic oxygen compound - Carbonyl group - Organic nitrogen compound - Aliphatic heteromonocyclic compound
• Description: This compound belongs to the class of organic compounds known as alpha amino acids and derivatives. These are amino acids in which the amino group is attached to the carbon atom immediately adjacent to the carboxylate group (alpha carbon), or a derivative thereof.
• External Descriptors: Not available

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

Chemical and Physical Properties

• Sensitivity: Moisture Sensitive,Heat Sensitive
• Melt Point(°C): 187 °C
• Molecular Weight: 252.180 g/mol
• XLogP3: -1.500
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 6
• Rotatable Bond Count: 4
• Exact Mass: 252.038 Da
• Monoisotopic Mass: 252.038 Da
• Topological Polar Surface Area: 101.000 Ų
• Heavy Atom Count: 18
• Formal Charge: 0
• Complexity: 461.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 0
• Undefined Atom Stereocenter Count: 0
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 1

References

1. Gao Bao, Ding Yu, Cai Zhihe, Wu Shi, Wang Juan, Ling Na, Ye Qinghua, Chen Moutong, Zhang Youxiong, Wei Xianhu, Ye Yingwang, Wu Qingping.  (2024)  Dual-recognition colorimetric platform based on porous Au@Pt nanozymes for highly sensitive washing-free detection of Staphylococcus aureus.  MICROCHIMICA ACTA,  191  (7): (1-10).  [PMID:38951285] [10.1007/s00604-024-06460-8]