mTOR Inhibitor-1 - ≥98% , CAS No.468747-17-3

CAS: 468747-17-3 Cat. No.: M405098 Molecular Weight: 363.21

GRADE & PURITY ≥98%

Synonyms

3-Bromo-4-methylbenzoic Acid 2-[1-(2,4-Dihydroxyphenyl)ethylidene]hydrazide | (E)-3-Bromo-N'-[1-(2,4-dihydroxyphenyl)ethylidene]-4-methylbenzohydrazide | (E)-3-bromo-N'-(1-(2,4-dihydroxyphenyl)ethylidene)-4-methylbenzohydrazide

Storage

Store at -20°C,Argon charged

Shipped In

Ice chest + Ice pads

Specifications

Synonyms

3-Bromo-4-methylbenzoic Acid 2-[1-(2, 4-Dihydroxyphenyl)ethylidene]hydrazide | (E)-3-Bromo-N'-[1-(2, 4-dihydroxyphenyl)ethylidene]-4-methylbenzohydrazide | (E)-3-bromo-N'-(1-(2, 4-dihydroxyphenyl)ethylidene)-4-methylbenzohydrazide

Specifications & Purity

≥98%

Biochemical and Physiological Mechanisms

The addition of C-4 (mTOR inhibitor-1, 0~12.8 μg/ml) directly decreases the level of activated mTOR (p-mTORser2448) which is phosphorylated at Ser2448. The proliferation of A549 cells is strongly inhibited by C-4, and the inhibitory effect is time- and do

Storage

Store at -20°C, Argon charged

Shipped In

Ice chest + Ice pads

This product requires cold chain shipping. Ground and other economy services are not available.

Purity

≥98%

Names and Identifiers

• Pubchem Sid: 504760364
• Pubchem Sid Url: https://pubchem.ncbi.nlm.nih.gov/substance/504760364
• Canonical Smiles: CC1=C(C=C(C=C1)C(=O)NN=C(C)C2=C(C=C(C=C2)O)O)Br
• IUPAC Name: 3-bromo-N-[1-(2,4-dihydroxyphenyl)ethylideneamino]-4-methylbenzamide
• InChIKey: NKMSVTGHOVMMHV-UHFFFAOYSA-N
• INCHI: 1S/C16H15BrN2O3/c1-9-3-4-11(7-14(9)17)16(22)19-18-10(2)13-6-5-12(20)8-15(13)21/h3-8,20-21H,1-2H3,(H,19,22)
• Isomeric SMILES: CC1=C(C=C(C=C1)C(=O)NN=C(C)C2=C(C=C(C=C2)O)O)Br
• Molecular Weight: 363.21
• Reaxy-Rn: 33612622
• Reaxys-RN_link_address: https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=33612622&ln=

Chemical and Physical Properties

• Solubility: ≥41.9 mg/mL in DMSO
• Sensitivity: Air Sensitive,Heat Sensitive
• Melt Point(°C): 262 °C