Mutated EGFR-IN-1 - 10mM in DMSO , CAS No.1421372-66-8

CAS: 1421372-66-8 Cat. No.: M656909 Molecular Weight: 445.6 EC Number: 187-892-6 PubChem CID: 78358313

GRADE & PURITY 10mM in DMSO

Storage

Store at -80°C

Shipped In

Dry ice packs + Cold packs

Overview

Mutated EGFR-IN-1 (Osimertinib analog) is a useful intermediate for the inhibitors design for mutated EGFR , such as L858R EGFR , Exonl9 deletion activating mutant and T790M resistance mutant.IC50 value:Target: Mutated EGFR inhibitor More information can be found in Patent WO 2013014448 A1.2 - (2, 4, 5 - substituted -anilino) pyrimidine derivatives as egfr modulators useful for treating cancer .

IC50& Target:EGFR L858R EGFR Exon 19 deletion/T790M EGFR T790M

Specifications

Specifications & Purity

10mM in DMSO

Biochemical and Physiological Mechanisms

Mutated EGFR-IN-1 (Osimertinib analog) is a useful intermediate for the inhibitors design for mutated EGFR , such as L858R EGFR , Exonl9 deletion activating mutant and T790M resistance mutant.\nIC50 value:\nTarget: Mutated EGFR inhibitor\nMore information

Storage

Store at -80°C

Shipped In

Dry ice packs + Cold packs

This product requires cold chain shipping. Ground and other economy services are not available.

Names and Identifiers

• Isomeric SMILES: CN1C=C(C2=CC=CC=C21)C3=NC(=NC=C3)NC4=C(C=C(C(=C4)N)N(C)CCN(C)C)OC
• PubChem CID: 78358313
• Molecular Weight: 445.6