N-(3-Aminopropyl)methacrylamide hydrochloride - ≥98%(HPLC) , CAS No.72607-53-5

CAS: 72607-53-5 Cat. No.: N129096 Molecular Weight: 178.66 EC Number: 662-677-4

GRADE & PURITY ≥98%(HPLC)

Synonyms

APMA | N-(3-Aminopropyl)methacrylamide, HCl | MFCD00078257 | 3-Methacrylamidopropylammonium Chloride

Storage

Protected from light,Store at -20°C,Argon charged

Shipped In

Ice chest + Ice pads

Overview

N-(3-Aminopropyl)methacrylamide hydrochloride  is an aminoalkyl methacrylamide which can be synthesized by adding 1,3-diaminopropane to 1,3-diaminopropane dihydrogen chloride solution and further mixing the solution with methacrylic anhydride and hydroquinone. It has a primary amine that provides attractive features such as pH-responsiveness, affinity for anionic drugs and conjugation for variety of chemical structures.

N-(3-Aminopropyl)methacrylamide hydrochloride can be used in the preparation of copolymers and cross-linked miscellas for gene delivery, drug delivery and diagnostics applications.

Specifications

Synonyms

APMA | N-(3-Aminopropyl)methacrylamide, HCl | MFCD00078257 | 3-Methacrylamidopropylammonium Chloride

Specifications & Purity

≥98%(HPLC)

Storage

Protected from light, Store at -20°C, Argon charged

Shipped In

Ice chest + Ice pads

This product requires cold chain shipping. Ground and other economy services are not available.

Purity

≥98%(HPLC)

Names and Identifiers

• Pubchem Sid: 504765428
• Pubchem Sid Url: https://pubchem.ncbi.nlm.nih.gov/substance/504765428
• Canonical Smiles: CC(=C)C(=O)NCCCN.Cl
• IUPAC Name: N-(3-aminopropyl)-2-methylprop-2-enamide;hydrochloride
• InChIKey: XHIRWEVPYCTARV-UHFFFAOYSA-N
• INCHI: 1S/C7H14N2O.ClH/c1-6(2)7(10)9-5-3-4-8;/h1,3-5,8H2,2H3,(H,9,10);1H
• Isomeric SMILES: CC(=C)C(=O)NCCCN.Cl
• WGK Germany: 3
• Molecular Weight: 178.66
• Reaxy-Rn: 9511076
• Reaxys-RN_link_address: https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=9511076&ln=

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Organic acids and derivatives
    • Class Carboxylic acids and derivatives
      • Subclass Carboxylic acid derivatives
        • Level5 Carboxylic acid amides
          • Level6 Secondary carboxylic acid amides

• Kingdom: Organic compounds
• Superclass: Organic acids and derivatives
• Class: Carboxylic acids and derivatives
• Subclass: Carboxylic acid derivatives
• Intermediate Tree Nodes: Carboxylic acid amides
• Direct Parent: Secondary carboxylic acid amides
• Alternative Parents: Amino acids and derivatives Organic oxides Monoalkylamines Hydrochlorides Hydrocarbon derivatives Carbonyl compounds
• Molecular Framework: Aliphatic acyclic compounds
• Substituents: Secondary carboxylic acid amide - Amino acid or derivatives - Organic nitrogen compound - Organic oxygen compound - Organic oxide - Hydrocarbon derivative - Hydrochloride - Primary amine - Organooxygen compound - Organonitrogen compound - Primary aliphatic amine - Carbonyl group - Amine - Aliphatic acyclic compound
• Description: This compound belongs to the class of organic compounds known as secondary carboxylic acid amides. These are compounds containing a secondary carboxylic acid amide functional group, with the general structure RC(=O)N(R')H (R,R'=alkyl, aryl).
• External Descriptors: Not available

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

Chemical and Physical Properties

• Sensitivity: Light & Air & Moisture & Heat Sensitive
• Melt Point(°C): 123-128°C
• Molecular Weight: 178.660 g/mol
• Hydrogen Bond Donor Count: 3
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 4
• Exact Mass: 178.087 Da
• Monoisotopic Mass: 178.087 Da
• Topological Polar Surface Area: 55.100 Ų
• Heavy Atom Count: 11
• Formal Charge: 0
• Complexity: 132.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 0
• Undefined Atom Stereocenter Count: 0
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 2

XLogP3

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