N-Phenylmaleimide - ≥98%(GC) , CAS No.941-69-5

CAS: 941-69-5 Cat. No.: N159011 Molecular Weight: 173.17 Beilstein Registry Number: 125098 EC Number: 213-382-0

GRADE & PURITY ≥98%(GC)

Synonyms

WLN: T5VNVJ BR | D77858 | EINECS 213-382-0 | N-PHENYLMALEIMIDE [MI] | N-phenylmaleinimde | NCGC00176508-01 | N-Phenylmaleimide, >=98.0% (HPLC) | Maleinanil | STR03760 | Tox21_300672 | 9U9KT462VW | HMS1473M19 | IDI1_019601 | N-phenyl maleimide | NSC8183 |

Storage

Room temperature,Argon charged

Shipped In

Normal

Overview

application：

N-Phenylmaleimide is used as a dipolarophile in 1,3-cycloaddition reaction with a nitrone, useful for the preparation of crystalline adducts of dienes. It is used as a plastic modifier.

Specifications

Synonyms

WLN: T5VNVJ BR | D77858 | EINECS 213-382-0 | N-PHENYLMALEIMIDE [MI] | N-phenylmaleinimde | NCGC00176508-01 | N-Phenylmaleimide, >=98.0% (HPLC) | Maleinanil | STR03760 | Tox21_300672 | 9U9KT462VW | HMS1473M19 | IDI1_019601 | N-phenyl maleimide | NSC8183 |

Specifications & Purity

≥98%(GC)

Storage

Room temperature, Argon charged

Shipped In

Normal

Purity

≥98%(GC)

Names and Identifiers

• Pubchem Sid: 504752481
• Pubchem Sid Url: https://pubchem.ncbi.nlm.nih.gov/substance/504752481
• Canonical Smiles: C1=CC=C(C=C1)N2C(=O)C=CC2=O
• IUPAC Name: 1-phenylpyrrole-2,5-dione
• InChIKey: HIDBROSJWZYGSZ-UHFFFAOYSA-N
• INCHI: 1S/C10H7NO2/c12-9-6-7-10(13)11(9)8-4-2-1-3-5-8/h1-7H
• Isomeric SMILES: C1=CC=C(C=C1)N2C(=O)C=CC2=O
• WGK Germany: 3
• RTECS: ON5950000
• UN Number: 2811
• Packing Group: I
• Molecular Weight: 173.17
• Beilstein: 125098
• Reaxy-Rn: 125098
• Reaxys-RN_link_address: https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=125098&ln=

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Organoheterocyclic compounds
    • Class Pyrrolines
      • Subclass Phenylpyrrolines

• Kingdom: Organic compounds
• Superclass: Organoheterocyclic compounds
• Class: Pyrrolines
• Subclass: Phenylpyrrolines
• Intermediate Tree Nodes: Not available
• Direct Parent: Phenylpyrrolines
• Alternative Parents: Maleimides N-substituted carboxylic acid imides Benzene and substituted derivatives Pyrroles Dicarboximides Azacyclic compounds Organopnictogen compounds Organonitrogen compounds Organic oxides Hydrocarbon derivatives Carbonyl compounds
• Molecular Framework: Aromatic heteromonocyclic compounds
• Substituents: 1-phenylpyrroline - Maleimide - Monocyclic benzene moiety - Carboxylic acid imide, n-substituted - Benzenoid - Carboxylic acid imide - Dicarboximide - Pyrrole - Carboxylic acid derivative - Azacycle - Carbonyl group - Organopnictogen compound - Organooxygen compound - Organonitrogen compound - Organic oxygen compound - Organic nitrogen compound - Organic oxide - Hydrocarbon derivative - Aromatic heteromonocyclic compound
• Description: This compound belongs to the class of organic compounds known as phenylpyrrolines. These are polycyclic aromatic compounds containing a benzene ring linked to a pyrroline ring through a CC or CN bond.
• External Descriptors: Not available

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

Associated Targets(Human)

CCRF-CEM (65223 Activities)

Explore this target

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

MCF7 (126967 Activities)

Explore this target

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

NCI-H460 (60772 Activities)

Explore this target

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

SF-268 (49410 Activities)

Explore this target

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

MGLL Tchem Monoglyceride lipase (1909 Activities)

Discover Target: MGLL

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

SETD7 Tchem Histone-lysine N-methyltransferase SETD7 (390 Activities)

Discover Target: SETD7

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Associated Targets(non-human)

Trypsin (394 Activities)

Explore this target

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Faah Anandamide amidohydrolase (3907 Activities)

Discover Target: Faah

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Nannizzia gypsea (2039 Activities)

Explore this target

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Aspergillus flavus (8875 Activities)

Explore this target

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Aspergillus niger (16508 Activities)

Explore this target

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Saccharomyces cerevisiae (19171 Activities)

Explore this target

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Pichia kudriavzevii (7448 Activities)

Explore this target

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Kluyveromyces marxianus (909 Activities)

Explore this target

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Aspergillus fumigatus (16427 Activities)

Explore this target

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Cryptococcus neoformans (21258 Activities)

Explore this target

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Candida albicans (78123 Activities)

Explore this target

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Nakaseomyces glabratus (9108 Activities)

Explore this target

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Candida parapsilosis (8521 Activities)

Explore this target

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Candida tropicalis (8381 Activities)

Explore this target

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Trichophyton rubrum (3646 Activities)

Explore this target

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Mus musculus (284745 Activities)

Explore this target

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Clavispora lusitaniae (671 Activities)

Explore this target

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

L1210 (27553 Activities)

Explore this target

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Trichophyton mentagrophytes (4846 Activities)

Explore this target

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Mechanisms of Action

Chemical and Physical Properties

• Solubility: Soluble in water (slightly ), methanol, ethanol, and benzene.
• Sensitivity: Air & Moisture Sensitive
• Flash Point(°F): 305.6 °F
• Flash Point(°C): 152 °C
• Boil Point(°C): 181°C/27mmHg
• Melt Point(°C): 85-87°C
• Molecular Weight: 173.170 g/mol
• XLogP3: 1.100
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 1
• Exact Mass: 173.048 Da
• Monoisotopic Mass: 173.048 Da
• Topological Polar Surface Area: 37.400 Ų
• Heavy Atom Count: 13
• Formal Charge: 0
• Complexity: 246.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 0
• Undefined Atom Stereocenter Count: 0
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 1

References

1. Liu Xing, Zhou Jianjun, Liu Shumei, Zhao Jianqing.  (2023)  Design and synthesis of thiol-terminated imidothioether oligomer as thermally latent hardener and modifier for high-performance epoxy/thiol thermosets.  Science China-Chemistry,      [PMID:] [10.1007/s11426-023-1771-6]

2. BY Hou, L Ren, YN Sun, MY Zhang, HX Zhang.  (2021)  Structure and properties of heat-resistant ABS resins innovated via MSAMI random copolymer.  JOURNAL OF THERMOPLASTIC COMPOSITE MATERIALS,      [PMID:] [10.1177/08927057211044191]

3. Jiemei Zhou, Chenxu Zhang, Cailong Shen, Yong Wang.  (2019)  Synthesis of poly(2-dimethylaminoethyl methacrylate)-block- poly(styrene-alt-N-phenylmaleimide) and its thermo-tolerant nanoporous films prepared by selective swelling.  POLYMER,      [PMID:] [10.1016/j.polymer.2019.01.013]

4. Yan Li, Tao Li, Long-Qiang Xiao, Yue-Fei Zhang.  (2018)  Novel Synthesis of Down-/Up-Conversion Fluorescent Oligo(2-pyrazoline)s.  INDUSTRIAL & ENGINEERING CHEMISTRY RESEARCH,      [PMID:] [10.1021/acs.iecr.8b02709]

5. Lulu He, Jinfen Lou, Xiang Nie, Min He, Qiao Fan, Jifei Yang, Yufei Liu, Shuhao Qin, Jie Yu.  (2024)  Highly enhanced toughness and thermal oxygen aging resistance of PA 6 via novel designed macromolecular antioxidants.  POLYMER,      [PMID:] [10.1016/j.polymer.2024.127614]

6. Xingyue You, Peng Wang, Yongke Tan, Yujing Li, Jieqiong Wang, Zixuan Li, Yuhui Ao, Ming Li.  (2024)  Photo-thermal double-crosslinked second-order nonlinear optical materials with high orientation stability.  Materials Today Chemistry,      [PMID:] [10.1016/j.mtchem.2024.101971]

7. Xing Liu, Zhenzhi Liu, Houqun Xiao, Lijing Han, Jianqing Zhao.  (2025)  Phosphorus-Containing Polyimidothioether as a Latent Curing Agent and Flame Retardant for One-Component Epoxy Resins.  ACS Applied Polymer Materials,      [PMID:] [10.1021/acsapm.5c02469]

8. Ruobing Xu, Qingming Xu, Wenfei Li, Yuming Liu, Yunhui Li, Jianwei Zhu, Jianhua Tang.  (2025)  Synthesis and Characterization of EPBT Low Temperature Cured Cationic Photosensitive Resin.  JOURNAL OF APPLIED POLYMER SCIENCE,      [PMID:] [10.1002/app.58138]