NASPM trihydrochloride , CAS No.1049731-36-3

CAS: 1049731-36-3 Cat. No.: N275304 Molecular Weight: 479.31 PubChem CID: 16219727

Synonyms

N-[3-[4-(3-Aminopropylamino)butylamino]propyl]-2-naphthalen-1-ylacetamidetrihydrochloride

Storage

Store at 2-8°C,Desiccated

Shipped In

Wet ice

Overview

Store at +4°C. Store under desiccating conditions. The product can be stored for up to 12 months.

Specifications

Synonyms

N-[3-[4-(3-Aminopropylamino)butylamino]propyl]-2-naphthalen-1-ylacetamidetrihydrochloride

Biochemical and Physiological Mechanisms

Selective, Ca 2+ -permeable AMPA receptor antagonist. Blocks GluR2 subunit lacking AMPA channels. Shows neuroprotective effects.

Storage

Store at 2-8°C, Desiccated

Shipped In

Wet ice

This product requires cold chain shipping. Ground and other economy services are not available.

Action Type

INHIBITOR

Note

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

Names and Identifiers

• Canonical Smiles: C1=CC=C2C(=C1)C=CC=C2CC(=O)NCCCNCCCCNCCCN.Cl.Cl.Cl
• IUPAC Name: N-[3-[4-(3-aminopropylamino)butylamino]propyl]-2-naphthalen-1-ylacetamide;trihydrochloride
• InChIKey: JNEOJAUJWOPWJS-UHFFFAOYSA-N
• INCHI: 1S/C22H34N4O.3ClH/c23-12-6-15-24-13-3-4-14-25-16-7-17-26-22(27)18-20-10-5-9-19-8-1-2-11-21(19)20;;;/h1-2,5,8-11,24-25H,3-4,6-7,12-18,23H2,(H,26,27);3*1H
• Isomeric SMILES: C1=CC=C2C(=C1)C=CC=C2CC(=O)NCCCNCCCCNCCCN.Cl.Cl.Cl
• PubChem CID: 16219727
• Molecular Weight: 479.31

Chemical and Physical Properties

• Solubility: Soluble in water to 100 mM
• Molecular Weight: 479.900 g/mol
• Hydrogen Bond Donor Count: 7
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 14
• Exact Mass: 478.203 Da
• Monoisotopic Mass: 478.203 Da
• Topological Polar Surface Area: 79.200 Ų
• Heavy Atom Count: 30
• Formal Charge: 0
• Complexity: 391.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 0
• Undefined Atom Stereocenter Count: 0
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 4

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