Nemolizumab (anti-IL-31Ra) - Primary antibody, for ELISA,Functional Assay,Flow cytometry,Kinetics (BLI),Kinetics (SPR) various applications, specific to IL31RA, >95%, Human IgG2, Antibody of Interleukin-31 receptor; α subunit, Antibody of Interleukin-31 receptor; α subunit

CAS: 1476039-58-3 Cat. No.: Ab170532
AVAILABLE TO ORDER
GRADE & PURITY Animal Free ? Animal-free — produced without animal-derived components to reduce contamination risk. Use in biomanufacturing and culture avoiding animal-origin material. Carrier Free ? Carrier-free — supplied without added carrier protein/stabilizer. Use when carriers (e.g. BSA) would interfere with conjugation or sensitive assays. Recombinant ? Recombinant — produced via recombinant expression for defined sequence and consistency. Use for reproducible, animal-free proteins of known origin. Validated ? Validated grade — performance confirmed in defined applications before release. Use when you want documented assurance the reagent works as stated. ExactAb™ ? ExactAb™ — Aladdin's antibody line emphasizing precision and validated quality. Use for reliable, specificity-validated antibody applications. Low Endotoxin ? Low-endotoxin grade — endotoxin reduced to low controlled levels. Use in sensitive biological work where high endotoxin would interfere. Azide Free ? Azide-free — without sodium azide preservative. Use in conjugations, cell work, or assays where azide is toxic or inhibitory. ≥95%(SDS-PAGE&SEC-HPLC) See COA
Application
IF/ICC
Host species
Human
Reactive species
Cynomolgus monkey, Human
Isotype
Human IgG2
Conjugation
Unconjugated
 ·  off list, applied to all prices below.
Size
Status
Price
Qty
100μg
Ab170532-100μg
10
$49.90
1mg
Ab170532-1mg
4
$309.90
5mg
Ab170532-5mg
1
$889.90
10mg
Ab170532-10mg
1-2 wks(?)
Item is derived from our semi-finished stock and is processed in 1-2 weeks.
$1,453.90
Enter a quantity for the sizes you want to add.
🧪

Why this grade

Carrier Free, Recombinant, ExactAb™, Low Endotoxin, Azide Free, Validated, Animal Free, ≥95%(SDS-PAGE&SEC-HPLC), See COA Animal Free,Azide Free,Carrier Free,ExactAb™,Low Endotoxin,Recombinant,Validated for sensitive chromatographic and analytical workflows requiring minimal baseline interference.

🌡

Storage & shipping

Store at -80°C,Avoid repeated freezing and thawing Ships Dry ice packs + Cold packs Check lot-specific COA for exact specifications.

📋

Quality documents

SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.

📚

Literature proof

Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.

Overview

Nemolizumab (anti-IL-31Ra) is a humanized antihuman interleukin-31 receptor A monoclonal antibody that inhibits the binding of interleukin-31 (IL-31) to its receptor and subsequent signal transduction. Nemolizumab can used be in research of atopic dermatitis (AD).
Purity
>95% (SDS-PAGE&SEC)
Endotoxin Level
< 1.0EU/mg

Specifications

Product Name
Nemolizumab (anti-IL-31Ra) - Primary antibody, for ELISA,Functional Assay,Flow cytometry,Kinetics (BLI),Kinetics (SPR) various applications, specific to IL31RA, >95%, Human IgG2, Antibody of Interleukin-31 receptor; α subunit
Synonyms
Cytokine receptor-like 3 | GLM-R | Gp130-like monocyte receptor | Gp130-like receptor | hGLM-R | IL-31 receptor subunit alpha | IL-31R subunit alpha | IL-31RA | IL-31R-alpha | ZcytoR17
Specifications & Purity
Carrier Free, Recombinant, ExactAb™, Low Endotoxin, Azide Free, Validated, Animal Free, ≥95%(SDS-PAGE&SEC-HPLC), See COA
Host species
Human
Specificity
IL31RA
Application
ELISA, Functional Assay, Flow cytometry, Kinetics (BLI), Kinetics (SPR)
Conjugation
Unconjugated
Grade
Animal Free, Azide Free, Carrier Free, ExactAb™, Low Endotoxin, Recombinant, Validated
Action Type
INHIBITOR
Mechanism of action
Antibody of Interleukin-31 receptor; α subunit
Antibody Type
Primary antibody
Clonality
Recombinant
Isotype
Human IgG2
Light Chain Type
kappa
SDS-PAGE
26.5 kDa (Light Chain) & 54.0 kDa (Heavy Chain), under reducing conditions; 175.4 kDa, under non-reducing conditions.
Purification Method
Protein A purified
Purity
>95%
Source
CHO supernatant
Concentration
See COA
CAS
1476039-58-3
Storage and Shipping
Shape
Liquid
Storage
Store at -80°C,Avoid repeated freezing and thawing
Shipped In
Dry ice packs + Cold packs
Stability And Storage
Store at -80℃ for 24 months. Upon receipt, it is recommended to aliquot. Avoid freeze/thaw cycle.
Images

Nemolizumab (anti-IL-31Ra) (Ab170532) - SEC
The purity of Nemolizumab (anti-IL-31Ra) (Ab170532) is more than 95% verified by HPLC.

Nemolizumab (anti-IL-31Ra) (Ab170532) - ELISA
Immobilized Human IL-31RA - Fc tag at 2 μg/mL can bind Nemolizumab (anti-IL-31Ra) (Ab170532) with the EC₅₀ of 20.79 ng/mL.

Application
ApplicationDilution info
IF/ICC

1/50-1/200

Documentation

📋 Safety Data Sheet (SDS)

Comprehensive hazard, handling, storage, and regulatory compliance document.

Download SDS →

✅ Certificate of Analysis (COA)

Lot-specific quality data. Enter your lot number to retrieve the exact COA.

Look up COA →

📊 Datasheet

Quick-reference summary of product specifications and applications.

View datasheet →

🔬 Specification Sheet

Full quality attributes and acceptance criteria for this grade.

View spec sheet →

Advanced Data

Associated Targets(Human)
IL31RA Tbio Interleukin-31 receptor subunit alpha (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
Mechanisms of Action
Certificates(CoA,COO,BSE/TSE and Analysis Chart)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

3 results found

Lot NumberCertificate TypeDateItem
ZJ24F0303672Certificate of AnalysisMar 25, 2024 Ab170532
ZJ24F0303671Certificate of AnalysisMar 25, 2024 Ab170532
ZJ24F0303670Certificate of AnalysisMar 25, 2024 Ab170532
Solution Calculators
Reviews

Customer Reviews

Need help choosing the grade?

Our grade selection guide covers purity, stabilizer status, and application suitability for all variants in our catalog.

View Animal Free grade guide → View Carrier Free grade guide → View Recombinant grade guide → View Validated grade guide → View ExactAb™ grade guide → View Low Endotoxin grade guide → View Azide Free grade guide →

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