PEAQX tetrasodium hydrate - 10mM in Water , CAS No.P661679(Water)

CAS: P661679(Water) Cat. No.: P661679 Molecular Weight: 560.15

GRADE & PURITY 10mM in Water

Storage

Desiccated,Store at -80°C

Shipped In

Dry ice packs + Cold packs

Overview

PEAQX (NVP-AAM077) tetrasodium hydrate is a potent, selective and orally active NMDA antagonist, with IC 50 values of 270 nM and 29600 nM for hNMDAR 1A/2B and hNMDAR 1A/2B , respectively.

IC50& Target:NMDA Receptor

In Vitro:PEAQX (3 μM) produces similar caspase-3 activation, while NVP-AAM007 is approximately three-fold more potent. MCE has not independently confirmed the accuracy of these methods. They are for reference only.

In Vivo:PEAQX (10-40mg/kg) dose-dependently increased cortical caspase-3 activity following sub-chronic administration. ?\nPEAQX (10 and 20mg/kg) shows enhanced locomotor activity in response to PCP challenge (4mg/kg on PN28-35) compared to saline pretrea

Biological Activity:PEAQX (NVP-AAM077) tetrasodium hydrate is a potent, selective and orally active NMDA antagonist, with IC 50 values of 270 nM and 29600 nM for hNMDAR 1A/2B and hNMDAR 1A/2B , respectively.

Specifications

Specifications & Purity

10mM in Water

Storage

Desiccated, Store at -80°C

Shipped In

Dry ice packs + Cold packs

This product requires cold chain shipping. Ground and other economy services are not available.

Names and Identifiers

• Canonical Smiles: BrC1=CC=C([C@H](C)NC(P(O[Na])(O[Na])=O)C2=CC=CC3=C2N=C(O[Na])C(O[Na])=N3)C=C1.[H]O[H]
• Molecular Weight: 560.15