RAGE antagonist peptide TFA, CAS No.R659109

CAS: R659109 Cat. No.: R659109 Molecular Weight: 1386.58

GRADE & PURITY ≥99%

Overview

RAGE antagonist peptide TFA is an advanced glycation end products (RAGE) antagonist. RAGE antagonist peptide TFA prevents RAGE from binding with several of its most important ligands, including HMGB-1, S100P, and S100A4. RAGE antagonist peptide TFA posses

Appearance:Solid

In Vitro:RAGE antagonist peptide TFA (RAP) reduces the ability of the ligands to stimulate RAGE activation of NFκB in cancer cells in vitro. MCE has not independently confirmed the accuracy of these methods. They are for reference only.

In Vivo:RAGE antagonist peptide TFA (RAP, 100 µg) inhibits RAGE-mediated Basal NFκB Activity in PDAC cells in vivo. RAGE antagonist peptide TFA (RAP) reduces the growth and metastasis of pancreatic tumors and also inhibited glioma tumor growth. In mice

Biological Activity:RAGE antagonist peptide TFA is an advanced glycation end products (RAGE) antagonist. RAGE antagonist peptide TFA prevents RAGE from binding with several of its most important ligands, including HMGB-1, S100P, and S100A4. RAGE antagonist peptide TFA posses

Specifications

Product Name

RAGE antagonist peptide TFA, CAS No.R659109

Specifications & Purity

≥99%

CAS

R659109

Molecule Type

Peptide

Storage and Shipping

Storage

Desiccated,Store at -80°C

Shipped In

Dry ice packs + Cold packs