ROX NHS ester, 5-isomer - ≥85% , CAS No.344402-35-3

CAS: 344402-35-3 Cat. No.: R595125 Molecular Weight: 631.67

GRADE & PURITY ≥85%

Synonyms

J-019608 | AKOS040760034 | 5-ROX,SE | 5-Carboxy-X-rhodamine N-succinimidyl ester | 1H,5H,11H,15H-Xantheno[2,3,4-ij:5,6,7-i'j']diquinolizin-18-ium, 9-[2-carboxy-4-[[(2,5-dioxo-1-pyrrolidinyl)oxy]carbonyl]phenyl]-2,3,6,7,12,13,16,17-octahydro-, inner salt |

Storage

Store at -20°C

Shipped In

Ice chest + Ice pads

Overview

Extinction Coefficient Excitation Maximum: 82000; Fluorescence Quantum Yield: 1

ROX NHS ester, 5-isomer is a ROX dye derivative that is commonly used for oligonucleotide labeling. The NHS ester can react specifically and efficiently with primary amines such as the side chain of lysine residue or aminosilane-coated surfaces at neutral or slight basic conditions to form a covalent bond.

Specifications

Synonyms

J-019608 | AKOS040760034 | 5-ROX, SE | 5-Carboxy-X-rhodamine N-succinimidyl ester | 1H, 5H, 11H, 15H-Xantheno[2, 3, 4-ij:5, 6, 7-i'j']diquinolizin-18-ium, 9-[2-carboxy-4-[[(2, 5-dioxo-1-pyrrolidinyl)oxy]carbonyl]phenyl]-2, 3, 6, 7, 12, 13, 16, 17-octahydro-, inner salt |

Specifications & Purity

≥85%

Storage

Store at -20°C

Shipped In

Ice chest + Ice pads

This product requires cold chain shipping. Ground and other economy services are not available.

Purity

≥85%

Product Properties

• Excitation and Emision Ranges: λex 575 nm,λem 600 nm in 0.1 M phosphate pH 7.0

Names and Identifiers

• Canonical Smiles: C1CC2=C3C(=C4C(=C2)C(=C5C=C6CCC[N+]7=C6C(=C5O4)CCC7)C8=C(C=C(C=C8)C(=O)ON9C(=O)CCC9=O)C(=O)[O-])CCCN3C1
• Isomeric SMILES: C1CC2=CC3=C(C4=C2N(C1)CCC4)OC5=C6CCC[N+]7=C6C(=CC5=C3C8=C(C=C(C=C8)C(=O)ON9C(=O)CCC9=O)C(=O)[O-])CCC7
• Molecular Weight: 631.67
• Reaxy-Rn: 8749834
• Reaxys-RN_link_address: https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=8749834&ln=

Chemical and Physical Properties

• Solubility: Solubility in DMF, DMSO
• Molecular Weight: 631.700 g/mol
• XLogP3: 3.900
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 8
• Rotatable Bond Count: 4
• Exact Mass: 631.232 Da
• Monoisotopic Mass: 631.232 Da
• Topological Polar Surface Area: 119.000 Ų
• Heavy Atom Count: 47
• Formal Charge: 0
• Complexity: 1490.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 0
• Undefined Atom Stereocenter Count: 0
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 1