Inosine 5′-triphosphate trisodium salt - ≥96% , CAS No.35908-31-7

CAS: 35908-31-7 Cat. No.: I119531 Molecular Weight: 574.11 EC Number: 680-179-5 PubChem CID: 135742691

GRADE & PURITY ≥96%

Synonyms

ITP | MFCD00084678 | Inosine-5'-triphosphate trisodium salt | ITP | AC-8223 | Inosine 5'-triphosphate trisodium salt | Inosine-5'-triphosphatetrisodiumsalt | AKOS016009828 | trisodium;[[[(2R,3S,4R,5R)-3,4-dihydroxy-5-(6-oxo-1H-purin-9-yl)oxolan-2-yl]metho

Storage

Store at -20°C,Argon charged

Shipped In

Ice chest + Ice pads

Overview

Inosine 5′-triphosphate (ITP) is used in studies on the impact of deamination of ATP and GTP by various enzymes and chemical processes. ITP may be used as a substrate to study the specificity and kinetics of nucleoside-5′-triphosphatase and ATPase. ITP is also used to study activation of various ATPases and GTPases.

Specifications

Synonyms

ITP | MFCD00084678 | Inosine-5'-triphosphate trisodium salt | ITP | AC-8223 | Inosine 5'-triphosphate trisodium salt | Inosine-5'-triphosphatetrisodiumsalt | AKOS016009828 | trisodium;[[[(2R, 3S, 4R, 5R)-3, 4-dihydroxy-5-(6-oxo-1H-purin-9-yl)oxolan-2-yl]metho

Specifications & Purity

≥96%

Biochemical and Physiological Mechanisms

INOSINE 5′-triphosphate (ITP) has the ability to support the initiation of the effector system. It can prevent the hydrolysis of Guanosine 5'-guanosine-5'-triphosphate (GTP) , which is catalyzed by TD. Compared with GTP, ITP can skillfully induc

Storage

Store at -20°C, Argon charged

Shipped In

Ice chest + Ice pads

This product requires cold chain shipping. Ground and other economy services are not available.

Purity

≥96%

Names and Identifiers

• Pubchem Sid: 504773433
• Pubchem Sid Url: https://pubchem.ncbi.nlm.nih.gov/substance/504773433
• Canonical Smiles: C1=NC2=C(C(=O)N1)N=CN2C3C(C(C(O3)COP(=O)([O-])OP(=O)([O-])OP(=O)(O)[O-])O)O.[Na+].[Na+].[Na+]
• IUPAC Name: trisodium;[[[(2R,3S,4R,5R)-3,4-dihydroxy-5-(6-oxo-1H-purin-9-yl)oxolan-2-yl]methoxy-oxidophosphoryl]oxy-oxidophosphoryl] hydrogen phosphate
• InChIKey: QRGLCGLOQVQVCS-MSQVLRTGSA-K
• INCHI: 1S/C10H15N4O14P3.3Na/c15-6-4(1-25-30(21,22)28-31(23,24)27-29(18,19)20)26-10(7(6)16)14-3-13-5-8(14)11-2-12-9(5)17;;;/h2-4,6-7,10,15-16H,1H2,(H,21,22)(H,23,24)(H,11,12,17)(H2,18,19,20);;;/q;3*+1/p-3/t4-,6-,7-,10-;;;/m1.../s1
• Isomeric SMILES: C1=NC2=C(C(=O)N1)N=CN2[C@H]3[C@@H]([C@@H]([C@H](O3)COP(=O)([O-])OP(=O)([O-])OP(=O)(O)[O-])O)O.[Na+].[Na+].[Na+]
• WGK Germany: 1
• PubChem CID: 135742691
• Molecular Weight: 574.11

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Nucleosides, nucleotides, and analogues
    • Class Purine nucleotides
      • Subclass Purine ribonucleotides

• Kingdom: Organic compounds
• Superclass: Nucleosides, nucleotides, and analogues
• Class: Purine nucleotides
• Subclass: Purine ribonucleotides
• Intermediate Tree Nodes: Not available
• Direct Parent: Purine ribonucleoside triphosphates
• Alternative Parents: Purine ribonucleoside monophosphates Pentose phosphates Glycosylamines 6-oxopurines Hypoxanthines Monosaccharide phosphates Pyrimidones Alkyl phosphates N-substituted imidazoles Vinylogous amides Oxolanes Heteroaromatic compounds Secondary alcohols 1,2-diols Oxacyclic compounds Azacyclic compounds Organonitrogen compounds Hydrocarbon derivatives Organic zwitterions Organic oxides Organic sodium salts
• Molecular Framework: Aromatic heteropolycyclic compounds
• Substituents: Purine ribonucleoside triphosphate - Purine ribonucleoside monophosphate - Pentose phosphate - Pentose-5-phosphate - Glycosyl compound - N-glycosyl compound - 6-oxopurine - Hypoxanthine - Monosaccharide phosphate - Imidazopyrimidine - Purine - Pyrimidone - Alkyl phosphate - Monosaccharide - Pyrimidine - N-substituted imidazole - Phosphoric acid ester - Organic phosphoric acid derivative - Azole - Vinylogous amide - Imidazole - Heteroaromatic compound - Oxolane - 1,2-diol - Secondary alcohol - Oxacycle - Organic alkali metal salt - Azacycle - Organoheterocyclic compound - Organonitrogen compound - Hydrocarbon derivative - Alcohol - Organic zwitterion - Organic salt - Organic oxygen compound - Organic nitrogen compound - Organic sodium salt - Organooxygen compound - Organic oxide - Aromatic heteropolycyclic compound
• Description: This compound belongs to the class of organic compounds known as purine ribonucleoside triphosphates. These are purine ribobucleotides with a triphosphate group linked to the ribose moiety.
• External Descriptors: Not available

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

Chemical and Physical Properties

• Solubility: Methanol (Very Slightly, Heated), Water (Slightly)
• Sensitivity: Heat sensitive;Moisture sensitive
• Molecular Weight: 574.110 g/mol
• Hydrogen Bond Donor Count: 4
• Hydrogen Bond Acceptor Count: 16
• Rotatable Bond Count: 8
• Exact Mass: 573.926 Da
• Monoisotopic Mass: 573.926 Da
• Topological Polar Surface Area: 277.000 Ų
• Heavy Atom Count: 34
• Formal Charge: 0
• Complexity: 862.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 4
• Undefined Atom Stereocenter Count: 0
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 4

XLogP3