Determine the necessary mass, volume, or concentration for preparing a solution.
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
|---|
Moligand™, ≥98% Moligand™ for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
Protected from light,Room temperature Ships Normal Check lot-specific COA for exact specifications.
SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
Cited in 15 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
| Pubchem Sid | 488179893 |
|---|---|
| Pubchem Sid Url | https://pubchem.ncbi.nlm.nih.gov/substance/488179893 |
| Canonical Smiles | C1=CC(=CC=C1N)S(=O)(=O)N=C(N)N |
| IUPAC Name | 2-(4-aminophenyl)sulfonylguanidine |
| InChIKey | BRBKOPJOKNSWSG-UHFFFAOYSA-N |
| INCHI | 1S/C7H10N4O2S/c8-5-1-3-6(4-2-5)14(12,13)11-7(9)10/h1-4H,8H2,(H4,9,10,11) |
| Isomeric SMILES | C1=CC(=CC=C1N)S(=O)(=O)N=C(N)N |
| RTECS | WO8575000 |
| PubChem CID | 5324 |
| Molecular Weight | 214.24 |
| Beilstein | 5659891 |
| Reaxy-Rn | 747716 |
Comprehensive hazard, handling, storage, and regulatory compliance document.
Download SDS →Lot-specific quality data. Enter your lot number to retrieve the exact COA.
Look up COA →Full quality attributes and acceptance criteria for this grade.
View spec sheet →Taxonomy Tree
| Kingdom | Organic compounds |
|---|---|
| Superclass | Benzenoids |
| Class | Benzene and substituted derivatives |
| Subclass | Benzenesulfonamides |
| Intermediate Tree Nodes | Not available |
| Direct Parent | Benzenesulfonamides |
| Alternative Parents | Benzenesulfonyl compounds Aniline and substituted anilines Sulfonyls Organosulfonic acids and derivatives Guanidines Primary amines Organopnictogen compounds Organic oxides Hydrocarbon derivatives |
| Molecular Framework | Aromatic homomonocyclic compounds |
| Substituents | Benzenesulfonamide - Benzenesulfonyl group - Aniline or substituted anilines - Organic sulfonic acid or derivatives - Organosulfonic acid or derivatives - Sulfonyl - Guanidine - Organic oxygen compound - Organic nitrogen compound - Amine - Primary amine - Organosulfur compound - Organonitrogen compound - Hydrocarbon derivative - Organopnictogen compound - Organic oxide - Aromatic homomonocyclic compound |
| Description | This compound belongs to the class of organic compounds known as benzenesulfonamides. These are organic compounds containing a sulfonamide group that is S-linked to a benzene ring. |
| External Descriptors | Not available |
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
|---|
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
Find and download the COA for your product by matching the lot number on the packaging.
| Lot Number | Certificate Type | Date | Item |
|---|---|---|---|
| Certificate of Analysis | Feb 13, 2025 | S107128 | |
| Certificate of Analysis | Feb 13, 2025 | S107128 | |
| Certificate of Analysis | Feb 13, 2025 | S107128 | |
| Certificate of Analysis | Jun 28, 2024 | S107128 | |
| Certificate of Analysis | Jun 28, 2024 | S107128 | |
| Certificate of Analysis | Jun 28, 2024 | S107128 | |
| Certificate of Analysis | Dec 25, 2023 | S107128 | |
| Certificate of Analysis | Dec 13, 2023 | S107128 | |
| Certificate of Analysis | Jan 11, 2023 | S107128 | |
| Certificate of Analysis | Jan 11, 2023 | S107128 | |
| Certificate of Analysis | Jan 11, 2023 | S107128 | |
| Certificate of Analysis | Jan 11, 2023 | S107128 | |
| Certificate of Analysis | Nov 19, 2022 | S107128 | |
| Certificate of Analysis | Jul 19, 2022 | S107128 |
| Solubility | Solubility in water: Practically insoluble; Slightly soluble in Alcohol; Insoluble in Ether |
|---|---|
| Sensitivity | Light sensitive. |
| Melt Point(°C) | 190-193°C |
| Molecular Weight | 214.250 g/mol |
| XLogP3 | -0.700 |
| Hydrogen Bond Donor Count | 3 |
| Hydrogen Bond Acceptor Count | 4 |
| Rotatable Bond Count | 2 |
| Exact Mass | 214.052 Da |
| Monoisotopic Mass | 214.052 Da |
| Topological Polar Surface Area | 133.000 Ų |
| Heavy Atom Count | 14 |
| Formal Charge | 0 |
| Complexity | 307.000 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 0 |
| Undefined Atom Stereocenter Count | 0 |
| Defined Bond Stereocenter Count | 0 |
| Undefined Bond Stereocenter Count | 0 |
| The total count of all stereochemical bonds | 0 |
| Covalently-Bonded Unit Count | 1 |
| 1. Meiling Ping, Wenchao Lv, Chen Yang, Qian Chen, Zongwen Wang, Fengfu Fu. (2023) A Paper-Based Multicolor Colorimetric Aptasensor for the Visual Determination of Multiple Sulfonamides Based on Aptamer-Functionalized Magnetic Beads and NADH–Ascorbic Acid-Mediated Gold Nanobipyramids. Chemosensors, 11 (7): (386). [PMID:] [10.3390/chemosensors11070386] |
| 2. Zongwen Wang, Xiating Li, Feng Zhang, Yu Gao, Jintian Cheng, FengFu Fu. (2023) Regulating the Growth Rate of Gold Nanobipyramids via a HCl-NADH-Ascorbic Acid System toward a Dual-Channel Multicolor Colorimetric Immunoassay for Simultaneously Screening and Detecting Multiple Sulfonamides. ANALYTICAL CHEMISTRY, [PMID:37382204] [10.1021/acs.analchem.3c01928] |
| 3. Chen-Ting Zhu, Kai-Yuan Huang, Qing-Lin Zhou, Xiang-Ping Zhang, Gang-Wei Wu, Hua-Ping Peng, Hao-Hua Deng, Wei Chen, Hamada A.A. Noreldeen. (2022) Multi-excitation wavelength of gold nanocluster-based fluorescence sensor array for sulfonamides discrimination. SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY, [PMID:36442343] [10.1016/j.saa.2022.122138] |
| 4. Rongfang Yan, Zhenhua Wen, Xuelian Hu, Wenxiu Wang, He Meng, Yang Song, Shuo Wang, Yiwei Tang. (2022) A sensitive sensing system based on fluorescence dipeptide nanoparticles for sulfadimethoxine determination. FOOD CHEMISTRY, [PMID:36413846] [10.1016/j.foodchem.2022.134963] |
| 5. Lixiang Zuo, Ran He, Li Wang, Yanli Wei. (2022) Phosphorescence aptasensing system for sulfadimethoxine with petal-like MoS2 nanosheets for signal amplification. SENSORS AND ACTUATORS B-CHEMICAL, [PMID:] [10.1016/j.snb.2022.131639] |
| 6. X. Lu, M. Yu, D. Wang, P. Xiu, C. Xu, A.F. Lee, X. Gu. (2021) Flame-retardant effect of a functional DOPO-based compound on lignin-based epoxy resins. Materials Today Chemistry, [PMID:] [10.1016/j.mtchem.2021.100562] |
| 7. Changjun Hu, Zhenkun Mao, Zhentao Li, Qiaoyan Li, Zilin Chen. (2021) Benzoic acid-modified monolithic column for separation of hydrophilic compounds by capillary electrochromatography with high content of water in mobile phase. JOURNAL OF CHROMATOGRAPHY A, [PMID:33957344] [10.1016/j.chroma.2021.462166] |
| 8. Peng Wang, Lei Chen, Hang Xiao, Tonghui Zhan. (2019) Nitrogen/sulfur-containing DOPO based oligomer for highly efficient flame-retardant epoxy resin. POLYMER DEGRADATION AND STABILITY, [PMID:] [10.1016/j.polymdegradstab.2019.109023] |
| 9. Dandan Qin, Wangyang Lu, Xiyi Wang, Nan Li, Xia Chen, Zhexin Zhu, Wenxing Chen. (2016) Graphitic Carbon Nitride from Burial to Re-emergence on Polyethylene Terephthalate Nanofibers as an Easily Recycled Photocatalyst for Degrading Antibiotics under Solar Irradiation. ACS Applied Materials & Interfaces, [PMID:27617344] [10.1021/acsami.6b07680] |
| 10. Zhen Yu, Yanlin Liu, Sheng Wang, Yajin Fang, Xiangyu Zhou, Zhaobin Tang, Jin Zhu, Junping Zhang. (2024) N-Sulfonyl Guanidine Urea to Design Ultrastrong, Stable, and Recyclable Associative Dynamic Polyurea Networks. MACROMOLECULES, [PMID:] [10.1021/acs.macromol.4c01575] |
| 11. Xiuling Li, Yuechuan Bi, Xiang Guan, Jiaqi Wang, Jinli Liu, Yingjie Zhao, Chunli Zhao, Zhuojian Li, Shurui Chi, Junnan Wang, Renjing Chen, Zixun Zhao, Zemin Wang, Xin Tong, Ninggui Ma, Han Liu, Zhiming Wang, Zongwen Liu, Yang Ren, Zhanhua Wei, Kebin Lin. (2025) High-Performance NIR-II Sn-Based Perovskite LEDs Enabled by the Functionalization of Sulfaguanidine. ADVANCED MATERIALS, [PMID:41416381] [10.1002/adma.202516632] |
| 12. Rongfang Yan, Xuelian Hu, Ning Zhang, Weihua Liu, Wenxiu Wang, Yiwei Tang. (2025) Novel self-assembled fluorescent tripeptide nanoparticle for sensitive detection of sulfadiazine. TALANTA, [PMID:40288190] [10.1016/j.talanta.2025.128168] |
| 13. Xu Jia Jia, Shao Ke Man, Chen Su Yan, Lin Zheng Zhong. (2025) Detection of Malachite Green Residues in Aquatic Products Based on Fluorescence of Rare Earth Complexes. Journal of Applied Spectroscopy, [PMID:] [10.1007/s10812-025-02014-9] |
| 14. Jian-Fei Wang, Wei-Dan Jiang, Pei Wu, Yao-Bin Ma, Hong-Yun Zhang, Yang Liu, Lu Zhang, Hai-Feng Mi, Lin Feng, Xiao-Qiu Zhou. (2026) Vitamin K is involved in liver protection and repair: Mitigating hepatotoxicity induced by the nitrite environment in grass carp (Ctenopharyngodon idella) by modulating Golgi function, hepatic stellate cells and mitochondrial dynamics. AQUACULTURE, [PMID:] [10.1016/j.aquaculture.2026.743635] |
| 15. Huiting Feng, Yuxin Yang, Ruiling Li, Yuting Yang, Zongwen Wang, FengFu Fu, Yue Lin. (2026) Employment of mixed aptamers and gold nanobipyramids toward a paper-based aptasensor for simultaneously visual screening and accurate detection of eight sulfonamides. SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY, [PMID:] [10.1016/j.saa.2026.127574] |
Our grade selection guide covers purity, stabilizer status, and application suitability for all variants in our catalog.
View Moligand™ grade guide →