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· · COA & SDS available for every product · Same-day shipping on in-stock items TCN 238 - Moligand™, ≥98%(HPLC) , Allosteric modulator of mGlu 4 receptor, CAS No.125404-04-8, Allosteric modulator of mGlu 4 receptor
GRADE & PURITY Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%(HPLC) Synonyms
BDBM50323546 | AKOS000278717 | MS-23068 | 4-[(1E)-2-phenylethenyl]pyrimidin-2-amine | GTPL6235 | Lu AF32615 | TCN 238 | 4-((e)-styryl)-pyrimidin-2-ylamine | 3-cyclohexyl-5-fluoro-6-methyl-7-(2-morpholin-4-ylethoxy)-4h-chromen-4-one | HY-14419 | J-005224 |
Shipped In
Ice chest + Ice pads
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Why this grade Moligand™, ≥98%(HPLC) Moligand™ for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
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Storage & shipping Store at -20°C Ships Ice chest + Ice pads Check lot-specific COA for exact specifications.
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Quality documents SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
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Literature proof Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
Specifications Synonyms
BDBM50323546 | AKOS000278717 | MS-23068 | 4-[(1E)-2-phenylethenyl]pyrimidin-2-amine | GTPL6235 | Lu AF32615 | TCN 238 | 4-((e)-styryl)-pyrimidin-2-ylamine | 3-cyclohexyl-5-fluoro-6-methyl-7-(2-morpholin-4-ylethoxy)-4h-chromen-4-one | HY-14419 | J-005224 |
Specifications & Purity
Moligand™, ≥98%(HPLC)
Biochemical and Physiological Mechanisms
Positive allosteric modulator of mGlu4receptors (EC50= 1.0μM for human and rat mGlu4receptors). Orally available and brain penetrant.
Shipped In
Ice chest + Ice pads
This product requires cold chain shipping. Ground and other economy services are not available.
Action Type
ALLOSTERIC MODULATOR
Mechanism of action
Allosteric modulator of mGlu 4 receptor
Names and Identifiers Canonical Smiles C1=CC=C(C=C1)C=CC2=NC(=NC=C2)N IUPAC Name 4-[(E)-2-phenylethenyl]pyrimidin-2-amine InChIKey LNUXNUNUGIHCPA-VOTSOKGWSA-N INCHI 1S/C12H11N3/c13-12-14-9-8-11(15-12)7-6-10-4-2-1-3-5-10/h1-9H,(H2,13,14,15)/b7-6+ Isomeric SMILES C1=CC=C(C=C1)/C=C/C2=NC(=NC=C2)N Alternate CAS 125404-04-8 PubChem CID 46911068 MeSH Entry Terms 3-cyclohexyl-5-fluoro-6-methyl-7-(2-morpholin-4-ylethoxy)-4H-chromen-4-one;CFMMC cpd Molecular Weight 197.24
Documentation 📋 Safety Data Sheet (SDS) Comprehensive hazard, handling, storage, and regulatory compliance document.
Download SDS → ✅ Certificate of Analysis (COA) Lot-specific quality data. Enter your lot number to retrieve the exact COA.
Look up COA → 📊 Datasheet Quick-reference summary of product specifications and applications.
View datasheet → 🔬 Specification Sheet Full quality attributes and acceptance criteria for this grade.
View spec sheet →
Advanced Data Taxonomic Classification Kingdom Organic compounds Superclass Benzenoids Class Benzene and substituted derivatives Subclass Styrenes Intermediate Tree Nodes Not available Direct Parent Styrenes Alternative Parents Aminopyrimidines and derivatives Heteroaromatic compounds Azacyclic compounds Primary amines Hydrocarbon derivatives Molecular Framework Aromatic heteromonocyclic compounds Substituents Styrene - Aminopyrimidine - Pyrimidine - Heteroaromatic compound - Azacycle - Organoheterocyclic compound - Organic nitrogen compound - Hydrocarbon derivative - Primary amine - Organonitrogen compound - Amine - Aromatic heteromonocyclic compound Description This compound belongs to the class of organic compounds known as styrenes. These are organic compounds containing an ethenylbenzene moiety. External Descriptors Not available Data sources 1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.
3D Structure Associated Targets(Human) Associated Targets(non-human) Mechanisms of Action Certificates（CoA,COO,BSE/TSE and Analysis Chart) Chemical and Physical Properties Solubility Solvent:DMSO, Max Conc. mg/mL: 19.72, Max Conc. mM: 100; Solvent:ethanol, Max Conc. mg/mL: 1.97, Max Conc. mM: 10 Molecular Weight 197.240 g/mol XLogP3 2.200 Hydrogen Bond Donor Count 1 Hydrogen Bond Acceptor Count 3 Rotatable Bond Count 2 Exact Mass 197.095 Da Monoisotopic Mass 197.095 Da Topological Polar Surface Area 51.800 Ų Heavy Atom Count 15 Formal Charge 0 Complexity 209.000 Isotope Atom Count 0 Defined Atom Stereocenter Count 0 Undefined Atom Stereocenter Count 0 Defined Bond Stereocenter Count 1 Undefined Bond Stereocenter Count 0 The total count of all stereochemical bonds 1 Covalently-Bonded Unit Count 1
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