Tetrakis(4-aminophenyl)methane - ≥95% , CAS No.60532-63-0

CAS: 60532-63-0 Cat. No.: T194152 Molecular Weight: 380.48 EC Number: 806-109-7 PubChem CID: 11825069

GRADE & PURITY ≥95%

Synonyms

4,4',4'',4'''-Methanetetrayltetraaniline | TAM | TAPM

Storage

Store at 2-8°C,Argon charged

Shipped In

Wet ice

Specifications

Synonyms

4, 4', 4'', 4'''-Methanetetrayltetraaniline | TAM | TAPM

Specifications & Purity

≥95%

Storage

Store at 2-8°C, Argon charged

Shipped In

Wet ice

This product requires cold chain shipping. Ground and other economy services are not available.

Purity

≥95%

Names and Identifiers

• Pubchem Sid: 488197772
• Pubchem Sid Url: https://pubchem.ncbi.nlm.nih.gov/substance/488197772
• Canonical Smiles: C1=CC(=CC=C1C(C2=CC=C(C=C2)N)(C3=CC=C(C=C3)N)C4=CC=C(C=C4)N)N
• IUPAC Name: 4-[tris(4-aminophenyl)methyl]aniline
• InChIKey: LNHGLSRCOBIHNV-UHFFFAOYSA-N
• INCHI: 1S/C25H24N4/c26-21-9-1-17(2-10-21)25(18-3-11-22(27)12-4-18,19-5-13-23(28)14-6-19)20-7-15-24(29)16-8-20/h1-16H,26-29H2
• Isomeric SMILES: C1=CC(=CC=C1C(C2=CC=C(C=C2)N)(C3=CC=C(C=C3)N)C4=CC=C(C=C4)N)N
• PubChem CID: 11825069
• Molecular Weight: 380.48

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Benzenoids
    • Class Benzene and substituted derivatives
      • Subclass Aniline and substituted anilines

• Kingdom: Organic compounds
• Superclass: Benzenoids
• Class: Benzene and substituted derivatives
• Subclass: Aniline and substituted anilines
• Intermediate Tree Nodes: Not available
• Direct Parent: Aniline and substituted anilines
• Alternative Parents: Primary amines Hydrocarbon derivatives
• Molecular Framework: Aromatic homomonocyclic compounds
• Substituents: Aniline or substituted anilines - Organic nitrogen compound - Hydrocarbon derivative - Primary amine - Organonitrogen compound - Amine - Aromatic homomonocyclic compound
• Description: This compound belongs to the class of organic compounds known as aniline and substituted anilines. These are organic compounds containing an aminobenzene moiety.
• External Descriptors: Not available

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

Chemical and Physical Properties

• Sensitivity: air sensitive
• Melt Point(°C): 320 °C(dec.)
• Molecular Weight: 380.500 g/mol
• XLogP3: 4.200
• Hydrogen Bond Donor Count: 4
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 4
• Exact Mass: 380.2 Da
• Monoisotopic Mass: 380.2 Da
• Topological Polar Surface Area: 104.000 Ų
• Heavy Atom Count: 29
• Formal Charge: 0
• Complexity: 397.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 0
• Undefined Atom Stereocenter Count: 0
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 1

References

1. Zhiwei Mei, Haihan Li, Guanbo Wang, Yanqi Mao, Yuncun Xu, Jiaming Guo, Qingyu Li, Huaifeng Li, Wenqiong Li, Yanmei Tang, Xiaoguang Liang.  (2023)  Solvent-free and in situ synthesis of three-dimensional covalent organic frameworks thin films on Zn anodes for Zn–air batteries.  APPLIED SURFACE SCIENCE,      [PMID:] [10.1016/j.apsusc.2022.156324]

2. Shu-Qing Fu, Ming-Zhi Zhu, Boxin Xue, Pei-Nian Liu.  (2022)  Synergy between Ionic Capacity and Intrinsic Porosity in Imidazolium-Based Cationic Organic Polymers and Its Effect on Anionic Dye Adsorption.  MACROMOLECULES,      [PMID:] [10.1021/acs.macromol.2c01127]

3. Yalin Huang, Mu Ding, Jie Ding, Jinyang Kang, Zijun Yan, Pengwei Zhao, Xiaoyuan Zhou, Yongdong Jin, Shanyong Chen, Chuanqin Xia.  (2022)  Targeted synthesis of a high-stability cationic porous aromatic framework for highly efficient remediation of 99TcO4−.  CHEMICAL ENGINEERING JOURNAL,      [PMID:] [10.1016/j.cej.2022.134785]

4. Yue Zhao, Da-Peng Wang, Guang-Long Zhang, Jin-Wei Zhang, Ji-Yong Zheng, Cun-Guo Lin.  (2025)  Composite 2D–3D carbon-based GO/COF-300@BTA nanocontainer endowing PVB coatings with mechanical enhancement, active and passive corrosion protection properties.  Surfaces and Interfaces,      [PMID:] [10.1016/j.surfin.2025.105772]

5. Yang Liu, Xiaoyu Du, Yanqing Qu, Hongge Jia, Shuangping Xu, Mingyu Zhang.  (2024)  Fabrication of smart spherical three-dimensional covalent organic framework membranes with switchable oil–water separation via interfacial polymerization.  SEPARATION AND PURIFICATION TECHNOLOGY,      [PMID:] [10.1016/j.seppur.2024.131074]

6. Lianlian Chen, Dingyu Zheng, Fuxing Zhai, Lixin Xu, Huijian Ye.  (2025)  High-temperature energy storage capability of flexible polyimide film incorporated with compatible covalent organic framework.  JOURNAL OF POWER SOURCES,      [PMID:] [10.1016/j.jpowsour.2025.236204]

7. Yanqing Qu, Yang Liu, Xiaoyu Du, Hongge Jia, Shuangping Xu, Mingyu Zhang, Bingyang Liu.  (2024)  Photocatalytic and fouling resistant MXene/3D-S-COF for efficient oil-water emulsion separation.  SEPARATION AND PURIFICATION TECHNOLOGY,      [PMID:] [10.1016/j.seppur.2024.128242]

8. Huimin Chen, Xin Li, Wenjiang Li, Aoao Lu, Chenguang Li, Qiang Li, Dabin Liu, Hongfei Ma, Binbin Wang.  (2025)  Porous organic polymers containing Tröger's base for enhanced NOx adsorption.  POLYMER DEGRADATION AND STABILITY,      [PMID:] [10.1016/j.polymdegradstab.2025.111548]

9. Manyan Qiu, Aiai Nie, Jinghang Zhang, Miao Zheng, Ning Guan, Sharuna De, Xiaoyan Pei, Xinyan Yang, Yujun Jiang, Qianyu Zhao, Chaoxin Man.  (2025)  Magnetic Solid-phase Extraction and HPLC-UV Determination of Fat-soluble Vitamins based on a Multifunctional Monomer Covalent Organic Frameworks.  TALANTA,      [PMID:40669329] [10.1016/j.talanta.2025.128569]

10. Cheng-Ye Zhu, Jia-Hui Xin, Chao Zhang, Hao-Cheng Yang, Hong-Qing Liang, Zhi-Kang Xu.  (2025)  Designing polyurea membranes with twisted and durable skeleton for thermal/acid-stable efficient dye/salt separation.  JOURNAL OF MEMBRANE SCIENCE,      [PMID:] [10.1016/j.memsci.2025.124770]

11. Jinling Pang, Hongzhe Chen, Huige Guo, Kunning Lin, Shuyuan Huang, Beichen Lin, Yuanbiao Zhang.  (2024)  High-sensitive determination of tetracycline antibiotics adsorbed on microplastics in mariculture water using pre-COF/monolith composite-based in-tube solid phase microextraction on-line coupled to HPLC-MS/MS.  JOURNAL OF HAZARDOUS MATERIALS,      [PMID:38422729] [10.1016/j.jhazmat.2024.133768]

12. Yu-Ren Xue, Guang-Chang Xu, Kai Li, Xin-Yu Guo, Jian Wu, Hong-Qing Liang, Hao-Cheng Yang, Chao Zhang, Zhi-Kang Xu.  (2025)  Ultrathin and Stable Ionic Liquid Membranes with Bio-Inspired Interlocking Architecture for CO2 Separation.  Small,      [PMID:40326186] [10.1002/smll.202503418]

13. Hailiang Nie, Xiaoyu Du, Yanqing Qu, Yang Liu, Hongge Jia, Yutong Chen, Yan Wang, Wei Yang.  (2025)  Carboxyl-functionalized 3D imine-linked covalent organic framework for high-efficiency adsorption of cationic dyes.  APPLIED SURFACE SCIENCE,      [PMID:] [10.1016/j.apsusc.2025.165373]

14. Yun-Jie Li, Yun-Qiao Zhao, Tian-Jian Xiong, Ren-Xiu He, Hao Wang, Bang-Jin Wang, Jun-Hui Zhang, Sheng-Ming Xie, Kun-Ming Jiang, Li-Ming Yuan.  (2025)  Chiral Covalent Organic Framework Composite CCOF-301@SiO2 for Multi-Mode HPLC Enantiomeric Separation.  JOURNAL OF SEPARATION SCIENCE,  48  (11): (e70322).  [PMID:41258985] [10.1002/jssc.70322]

15. Jianquan Peng, Siheng Zhao, Shengchao Zhao, Mingbin Chen, Kuo Chen, Q. Jason Niu.  (2026)  Synthesis of Thin Film Composite Membranes via Acid-Assisted Interfacial Polymerization for Water Desalination.  WATER RESEARCH,      [PMID:41679037] [10.1016/j.watres.2026.125517]

16. Ziyu Liu, Xin Wen, Chenqi Yi, Zongsong Gan.  (2026)  Laser Ultrafast In Situ-Integrated COF Crystals.  Journal of Physical Chemistry Letters,      [PMID:] [10.1021/acs.jpclett.5c03733]