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TG100713 - ≥97% , CAS No.925705-73-3

CAS: 925705-73-3 Cat. No.: T129620 Molecular Weight: 254.25 PubChem CID: 17751063
COA
TG100713 - ≥97% CAS No(925705-73-3) by Aladdin Scientific
AVAILABLE TO ORDER
GRADE & PURITY ≥97%
Synonyms
A902741 | BCP05993 | s2870 | BDBM25082 | JMC504279 Compound 17 | 3-(2,4-DiaMino-6-pteridinyl)-phenol;TG 100713 | TG100713 | tg-100713 | J-510465 | HMS3651N21 | TG 100713 | Phenol, 3-(2,4-diamino-6-pteridinyl)- | AS-56116 | SCHEMBL369049 | UOORQSPLBHUQDQ-U
Storage
Room temperature
Shipped In
Normal
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 ·  off list, applied to all prices below.
Size
Status
Price
Qty
10mg
T129620-10mg
3

$61.90

$92.90
Save $31.00 (33.37%)
50mg
T129620-50mg
3

$178.90

$268.90
Save $90.00 (33.47%)
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SDS
Safety data
COA
Certificate
DS
Datasheet
SP
Spec sheet
Overview Specifications Names and Identifiers Documentation Advanced Data Taxonomic Classification 3D Structure Associated Targets(Human) Associated Targets(non-human) Mechanisms of Action Certificates（CoA,COO,BSE/TSE and Analysis Chart) Chemical and Physical Properties Solution Calculators Reviews
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Why this grade

≥97% for sensitive chromatographic and analytical workflows requiring minimal baseline interference.

🌡

Storage & shipping

Room temperature Ships Normal Check lot-specific COA for exact specifications.

📋

Quality documents

SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.

📚

Literature proof

Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.

Overview

TG100713 is a pan-PI3K inhibitor against PI3Kγ, PI3Kδ, PI3Kα and PI3Kβ with IC50 of 50 nM, 24 nM, 165 nM and 215 nM, respectively
An inhibitor of PI3-kinase

Specifications

Synonyms
A902741 | BCP05993 | s2870 | BDBM25082 | JMC504279 Compound 17 | 3-(2, 4-DiaMino-6-pteridinyl)-phenol;TG 100713 | TG100713 | tg-100713 | J-510465 | HMS3651N21 | TG 100713 | Phenol, 3-(2, 4-diamino-6-pteridinyl)- | AS-56116 | SCHEMBL369049 | UOORQSPLBHUQDQ-U
Specifications & Purity
≥97%
Biochemical and Physiological Mechanisms
TG 100713 is an inhibitor of PI3-kinase (IC50 values are 24, 50, 165 and 215 nM for PI3Kδ, γ, α and β isoforms respectively). TG 100713 also inhibits endothelial cell proliferation.
Storage
Room temperature
Shipped In
Normal
Purity
≥97%
Names and Identifiers
Pubchem Sid504768635
Pubchem Sid Urlhttps://pubchem.ncbi.nlm.nih.gov/substance/504768635
Canonical SmilesC1=CC(=CC(=C1)O)C2=CN=C3C(=N2)C(=NC(=N3)N)N
IUPAC Name3-(2,4-diaminopteridin-6-yl)phenol
InChIKeyUOORQSPLBHUQDQ-UHFFFAOYSA-N
INCHI1S/C12H10N6O/c13-10-9-11(18-12(14)17-10)15-5-8(16-9)6-2-1-3-7(19)4-6/h1-5,19H,(H4,13,14,15,17,18)
Isomeric SMILES C1=CC(=CC(=C1)O)C2=CN=C3C(=N2)C(=NC(=N3)N)N
PubChem CID 17751063
Molecular Weight 254.25

Documentation

📋 Safety Data Sheet (SDS)

Comprehensive hazard, handling, storage, and regulatory compliance document.

Download SDS →

✅ Certificate of Analysis (COA)

Lot-specific quality data. Enter your lot number to retrieve the exact COA.

Look up COA →

📊 Datasheet

Quick-reference summary of product specifications and applications.

View datasheet →

🔬 Specification Sheet

Full quality attributes and acceptance criteria for this grade.

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Advanced Data

Taxonomic Classification

Taxonomy Tree

KingdomOrganic compounds
SuperclassOrganoheterocyclic compounds
ClassPteridines and derivatives
SubclassNot available
Intermediate Tree Nodes Not available
Direct ParentPteridines and derivatives
Alternative Parents Aminopyrimidines and derivatives  1-hydroxy-4-unsubstituted benzenoids  1-hydroxy-2-unsubstituted benzenoids  Pyrazines  Imidolactams  Benzene and substituted derivatives  Heteroaromatic compounds  Azacyclic compounds  Primary amines  Organooxygen compounds  Hydrocarbon derivatives  
Molecular FrameworkAromatic heteropolycyclic compounds
Substituents Pteridine - Aminopyrimidine - 1-hydroxy-4-unsubstituted benzenoid - 1-hydroxy-2-unsubstituted benzenoid - Phenol - Monocyclic benzene moiety - Imidolactam - Benzenoid - Pyrimidine - Pyrazine - Heteroaromatic compound - Azacycle - Amine - Primary amine - Hydrocarbon derivative - Organooxygen compound - Organonitrogen compound - Organic oxygen compound - Organic nitrogen compound - Aromatic heteropolycyclic compound
DescriptionThis compound belongs to the class of organic compounds known as pteridines and derivatives. These are polycyclic aromatic compounds containing a pteridine moiety, which consists of a pyrimidine fused to a pyrazine ring to form pyrimido(4,5-b)pyrazine.
External Descriptors Not available
3D Structure
Interactive Chemical Structure Model





Associated Targets(Human)
PIK3CG Tclin PI3-kinase p110-gamma subunit (5411 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
PIK3CB Tchem PI3-kinase p110-beta subunit (4044 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
MCF7 (126967 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
A549 (127892 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
HepG2 (196354 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
HeLa (62764 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Associated Targets(non-human)
PIK3CA PI3-kinase p110-alpha subunit (51 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Hdac6 Histone deacetylase 6 (222 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
rep Replicase polyprotein 1ab (378 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Mechanisms of Action
Certificates（CoA,COO,BSE/TSE and Analysis Chart)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

1 results found

Lot NumberCertificate TypeDateItem
I1718041Certificate of AnalysisMar 07, 2023 T129620
Chemical and Physical Properties
Molecular Weight254.250 g/mol
XLogP30.400
Hydrogen Bond Donor Count3
Hydrogen Bond Acceptor Count7
Rotatable Bond Count1
Exact Mass254.092 Da
Monoisotopic Mass254.092 Da
Topological Polar Surface Area124.000 Ų
Heavy Atom Count19
Formal Charge0
Complexity317.000
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
The total count of all stereochemical bonds0
Covalently-Bonded Unit Count1
Solution Calculators
Reviews

Customer Reviews

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