Tolylene Diisocyanate (2,4, 2,6) (TDI) - ≥98%(GC) , CAS No.26471-62-5

CAS: 26471-62-5 Cat. No.: T135411 Molecular Weight: 174.16 EC Number: 247-722-4
AVAILABLE TO ORDER
GRADE & PURITY ≥98%(GC)
Synonyms
AI3-15101 | Benzene, diisocyanatomethyl- | NCGC00253965-01 | TOLUENE 2,4-DIISOCYANATE [HSDB] | Di-isocyanate de toluylene [French] | Hylene tcpa | NSC 4791 | 17X7AFZ1GH | Nacconate IOO | toluene-2,4-diyl diisocyanate | Diisocyanatomethylbenzene | 4-Methyl
Storage
Store at 2-8°C,Protected from light,Argon charged
Shipped In
Wet ice,FedEx DG Service
 ·  off list, applied to all prices below.
Size
Status
Price
Qty
25g
T135411-25g
8
$9.90
100g
T135411-100g
2

$11.90

$18.90
Save $7.00 (37.04%)
500g
T135411-500g
8-12 wks(?) Production requires sourcing of materials. We appreciate your patience and understanding.

$37.90

$54.90
Save $17.00 (30.97%)
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Why this grade

≥98%(GC) for sensitive chromatographic and analytical workflows requiring minimal baseline interference.

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Storage & shipping

Store at 2-8°C,Protected from light,Argon charged Ships Wet ice,FedEx DG Service Check lot-specific COA for exact specifications.

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Quality documents

SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.

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Literature proof

Cited in 96 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.

Specifications

Synonyms
AI3-15101 | Benzene, diisocyanatomethyl- | NCGC00253965-01 | TOLUENE 2, 4-DIISOCYANATE [HSDB] | Di-isocyanate de toluylene [French] | Hylene tcpa | NSC 4791 | 17X7AFZ1GH | Nacconate IOO | toluene-2, 4-diyl diisocyanate | Diisocyanatomethylbenzene | 4-Methyl
Specifications & Purity
≥98%(GC)
Storage
Store at 2-8°C, Protected from light, Argon charged
Shipped In
Wet ice, FedEx DG Service
This product requires cold chain shipping. Ground and other economy services are not available.
Purity
≥98%(GC)
Names and Identifiers
Pubchem Sid504752126
Pubchem Sid Urlhttps://pubchem.ncbi.nlm.nih.gov/substance/504752126
Isomeric SMILES CC1=C(C=C(C=C1)N=C=O)N=C=O
RTECS NQ9490000
Alternate CAS 584-84-9
UN Number 2078
Packing Group II
Molecular Weight 174.16
Reaxy-Rn 8188352

Documentation

📋 Safety Data Sheet (SDS)

Comprehensive hazard, handling, storage, and regulatory compliance document.

Download SDS →

✅ Certificate of Analysis (COA)

Lot-specific quality data. Enter your lot number to retrieve the exact COA.

Look up COA →

📊 Datasheet

Quick-reference summary of product specifications and applications.

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🔬 Specification Sheet

Full quality attributes and acceptance criteria for this grade.

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Advanced Data

Associated Targets(Human)
TRPA1 Tclin Transient receptor potential cation channel subfamily A member 1 (1 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
AR Tclin Androgen Receptor (11781 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
PPARG Tclin Peroxisome proliferator-activated receptor gamma (15191 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
AHR Tclin Aryl hydrocarbon receptor (1071 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CYP3A4 Tclin Cytochrome P450 3A4 (53859 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Lymphoblastoid cell (5959 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Associated Targets(non-human)
Trpa1 Transient receptor potential cation channel subfamily A member 1 (1003 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Nfe2l2 Nuclear factor erythroid 2-related factor 2 (214 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Rorc Nuclear receptor ROR-gamma (89407 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Mechanisms of Action
Certificates(CoA,COO,BSE/TSE and Analysis Chart)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

37 results found

Lot NumberCertificate TypeDateItem
K2503199Certificate of AnalysisOct 20, 2025 T135411
K2503198Certificate of AnalysisOct 20, 2025 T135411
K2503197Certificate of AnalysisOct 20, 2025 T135411
K2503196Certificate of AnalysisOct 20, 2025 T135411
K2503179Certificate of AnalysisOct 20, 2025 T135411
K2317061Certificate of AnalysisSep 04, 2025 T135411
D2525350Certificate of AnalysisAug 01, 2025 T135411
D2525351Certificate of AnalysisAug 01, 2025 T135411
E2329808Certificate of AnalysisApr 02, 2025 T135411
E2329809Certificate of AnalysisMar 03, 2025 T135411
E2329807Certificate of AnalysisMar 03, 2025 T135411
E2329806Certificate of AnalysisMar 03, 2025 T135411
L2424489Certificate of AnalysisDec 17, 2024 T135411
L2424107Certificate of AnalysisDec 17, 2024 T135411
L2424109Certificate of AnalysisDec 17, 2024 T135411
L2424112Certificate of AnalysisDec 17, 2024 T135411
I2509697Certificate of AnalysisJun 19, 2024 T135411
I2509698Certificate of AnalysisJun 19, 2024 T135411
D1823144Certificate of AnalysisOct 13, 2023 T135411
K2126312Certificate of AnalysisSep 20, 2023 T135411
E2422073Certificate of AnalysisMay 18, 2023 T135411
J2430707Certificate of AnalysisMay 18, 2023 T135411
E2329810Certificate of AnalysisMay 18, 2023 T135411
E2329805Certificate of AnalysisMay 18, 2023 T135411
C23161414Certificate of AnalysisMar 23, 2023 T135411
C2314369Certificate of AnalysisMar 23, 2023 T135411
J2312047Certificate of AnalysisFeb 13, 2023 T135411
E2112250Certificate of AnalysisFeb 13, 2023 T135411
C23241035Certificate of AnalysisFeb 13, 2023 T135411
J2222020Certificate of AnalysisOct 28, 2022 T135411
K2009364Certificate of AnalysisSep 13, 2022 T135411
D2319411Certificate of AnalysisSep 13, 2022 T135411
F2217266Certificate of AnalysisJun 30, 2022 T135411
B2216502Certificate of AnalysisJan 07, 2022 T135411
B2216509Certificate of AnalysisJan 07, 2022 T135411
B2216508Certificate of AnalysisJan 07, 2022 T135411
B2216506Certificate of AnalysisJan 07, 2022 T135411

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Chemical and Physical Properties
SolubilityMiscible with Ether,Benzene,Acetone
SensitivityHeat sensitive; Light sensitive; Moisture sensitive
Refractive Index1.57
Flash Point(°F)269.6 °F - closed cup
Flash Point(°C)132 °C - closed cup
Boil Point(°C)247 °C/1013 hPa
Melt Point(°C)12-14 °C
Molecular Weight174.160 g/mol
XLogP33.900
Hydrogen Bond Donor Count0
Hydrogen Bond Acceptor Count4
Rotatable Bond Count2
Exact Mass174.043 Da
Monoisotopic Mass174.043 Da
Topological Polar Surface Area58.900 Ų
Heavy Atom Count13
Formal Charge0
Complexity265.000
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
The total count of all stereochemical bonds0
Covalently-Bonded Unit Count1
Documents & Articles
A Complete Guide to Selecting Epoxy Curing Systems: Amines vs. Anhydrides vs. Latent Curing — with Aladdin’s Recommended Selection Table
Adding a Temperature-Triggered Switch to NCO: How Blocked Isocyanates Affect the Storage, Curing, and Film Performance of 1K Baking Coatings
How Do Isocyanates and Polyols Affect the Performance of Polyurethane Coating Films: Structure, Raw Material Selection, and Performance Design Essentials
1K, 2K, Waterborne, Moisture-Curing, and Blocked Systems: Classification Logic and Identification Methods for Polyurethane Coating Curing Systems
Key Control Points in Polyurethane Coating Formulation Design and Application
Film Formation and Curing Mechanisms of Polyester Resins for Coatings: From Functional Groups and Curing Systems to Crosslinked Networks
Polyurethane Coating Resins: Not a Single Resin, but a Designable High-Performance System
Applicability Boundaries, Failure Risks, and Alternative System Selection for Chlorinated Rubber Resin in Coatings
Mechanisms and Control of Coating Yellowing: From Chromophoric Structure Formation to Source Diagnosis and Formulation Optimization
Mechanism, Diagnosis, and Control of Coating Lifting: Solvent Penetration, Film Swelling, and Interlayer Instability
Resin Polarity in Coating Formulations: From Molecular Structure to Dissolution, Compatibility, Interfacial Interactions, and Formulation Design
Citations of This Product
References
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