(Trimethylsilyl)diazomethane - 2.0 M in hexanes , CAS No.18107-18-1

CAS: 18107-18-1 Cat. No.: T140538 Molecular Weight: 114.22 Beilstein Registry Number: 1902903 EC Number: 605-915-4 PubChem CID: 167693

GRADE & PURITY 2.0 M in hexanes

Synonyms

QI98HQO8C4 | TMSD | AT38821 | trimethylsilyl diazomethane | trimethyl-silyl diazomethane | diazomethyltrimethyl silane | EN300-74206 | Trimethlsilyl diazomethane | (Diazomethyl)trimethylsilane | (diazomethyl)-trimethylsilane | Q1990988 | trimethylsilyldia

Storage

Store at 2-8°C,Argon charged

Shipped In

Wet ice

Overview

Reactant for preparation of: &bull Macrolactam analogs of the natural product macrolide (-)-A26771B with improved metabolic stability and antibacterial activity &bull Aigialomycin D analogues as protein kinase inhibitors for cancer treatment &bull Unnatural α-amino acid derivatives containing gem-bisphosphonates via Michael addition reaction &bull Capped 4-methylumbelliferyl hyaluronan disaccharides and tetrasaccharides as potential hyaluronidase substrates &bull Stictamides A-C as matrix metallopeptidase 12 (MMP12) inhibitors with antitumor invasion activity &bull Endothelin converting enzyme (ECE) Inhibitors WS 75624A and WS 75624B via a cross-metathesis approach &bull Ent-kaurene derivatives as anti-inflammatory agents &bull Desmosdumotin C analogs as potent antitumor agents acting via activation of spindle assembly checkpoint &bull Imidazolo[2,1-b]benzothiazole derivatives as potential p53 inhibitors

Specifications

Synonyms

QI98HQO8C4 | TMSD | AT38821 | trimethylsilyl diazomethane | trimethyl-silyl diazomethane | diazomethyltrimethyl silane | EN300-74206 | Trimethlsilyl diazomethane | (Diazomethyl)trimethylsilane | (diazomethyl)-trimethylsilane | Q1990988 | trimethylsilyldia

Specifications & Purity

2.0 M in hexanes

Storage

Store at 2-8°C, Argon charged

Shipped In

Wet ice

This product requires cold chain shipping. Ground and other economy services are not available.

Names and Identifiers

• Canonical Smiles: C[Si](C)(C)C=[N+]=[N-]
• IUPAC Name: diazomethyl(trimethyl)silane
• InChIKey: ONDSBJMLAHVLMI-UHFFFAOYSA-N
• INCHI: 1S/C4H10N2Si/c1-7(2,3)4-6-5/h4H,1-3H3
• Isomeric SMILES: C[Si](C)(C)C=[N+]=[N-]
• WGK Germany: 3
• PubChem CID: 167693
• Molecular Weight: 114.22
• Beilstein: 1902903

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Organometallic compounds
    • Class Organometalloid compounds
      • Subclass Organosilicon compounds
        • Level5 Alkylsilanes
          • Level6 Trialkylsilanes

• Kingdom: Organic compounds
• Superclass: Organometallic compounds
• Class: Organometalloid compounds
• Subclass: Organosilicon compounds
• Intermediate Tree Nodes: Alkylsilanes
• Direct Parent: Trialkylsilanes
• Alternative Parents: Diazo compounds Organic metalloid salts Organopnictogen compounds Organonitrogen compounds Hydrocarbon derivatives
• Molecular Framework: Aliphatic acyclic compounds
• Substituents: Trialkylsilane - Diazo compound - Organic metalloid salt - Organic nitrogen compound - Organopnictogen compound - Hydrocarbon derivative - Organic salt - Organonitrogen compound - Aliphatic acyclic compound
• Description: This compound belongs to the class of organic compounds known as trialkylsilanes. These are organosilicon compounds containing exactly one alkyl chain attached to the silicon atom.
• External Descriptors: Not available

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

Chemical and Physical Properties

• Solubility: Immiscible with water. Miscible with organic solvents.
• Sensitivity: Heat & Moisture & Light Sensitive.
• Flash Point(°F): -9.4 °F
• Flash Point(°C): -23 °C
• Boil Point(°C): 96°C
• Molecular Weight: 114.220 g/mol
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 1
• Exact Mass: 114.061 Da
• Monoisotopic Mass: 114.061 Da
• Topological Polar Surface Area: 2.000 Ų
• Heavy Atom Count: 7
• Formal Charge: 0
• Complexity: 96.700
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 0
• Undefined Atom Stereocenter Count: 0
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 1
• The total count of all stereochemical bonds: 1
• Covalently-Bonded Unit Count: 1

XLogP3

References

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