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WNK1-IN-1 - ≥99% , CAS No.324022-39-1
AVAILABLE TO ORDER
GRADE & PURITY ≥99%
Storage
Store at -20°C
Shipped In
Ice chest + Ice pads
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Why this grade
≥99% for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
Storage & shipping
Store at -20°C Ships Ice chest + Ice pads Check lot-specific COA for exact specifications.
Quality documents
SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
Literature proof
Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
Overview
WNK1-IN-1 is a selective inhibitor of WNK1 with an IC 50 value of 1.6 μM. WNK1-IN-1 inhibits OSR1 phosphorylation with an IC 50 value of 4.3 μM. WNK1-IN-1 can be used for the research of blood pressure regulation and cancer
In Vitro
WNK1-IN-1 (0-1000 μM; 30 min) shows high potency to WNK1 with an IC 50 value of 1.6 μM. WNK1-IN-1 (0.2-12.5 μM; 24 h) inhibits endogenous OSR1 phosphorylation with an IC 50 value of 4.3 μM in MDAMB231 breast-cancer cells. WNK1-IN-1 (0-100 mM) is 10-fold more potent to WNK1 than WNK3 in Kinase-Glo assay. MCE has not independently confirmed the accuracy of these methods. They are for reference only.
Form:Solid
IC50& Target:IC50: 1.6 μM (WNK1), 4.3 μM (OSR1 phosphorylation)
Specifications
Specifications & Purity
≥99%
Biochemical and Physiological Mechanisms
WNK1-IN-1 is a selective inhibitor of WNK1 with an IC 50 value of 1.6 μM. WNK1-IN-1 inhibits OSR1 phosphorylation with an IC 50 value of 4.3 μM. WNK1-IN-1 can be used for the research of blood pressure regulation and cancer.
Storage
Store at -20°C
Shipped In
Ice chest + Ice pads
This product requires cold chain shipping. Ground and other economy services are not available.
Purity
≥99%
Names and Identifiers
| Molecular Weight | 446.14 |
|---|
Documentation
📋 Safety Data Sheet (SDS)
Comprehensive hazard, handling, storage, and regulatory compliance document.
Download SDS →✅ Certificate of Analysis (COA)
Lot-specific quality data. Enter your lot number to retrieve the exact COA.
Look up COA →🔬 Specification Sheet
Full quality attributes and acceptance criteria for this grade.
View spec sheet →Advanced Data
Certificates（CoA,COO,BSE/TSE and Analysis Chart)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:
Solution Calculators
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