ZINC00640089 - ≥99% , CAS No.667880-11-7

CAS: 667880-11-7 Cat. No.: Z649969 Molecular Weight: 370.32

GRADE & PURITY ≥99%

Storage

Store at -20°C

Shipped In

Ice chest + Ice pads

Overview

ZINC00640089 is a specific Lipocalin-2 ( LCN2 ) inhibitor. ZINC00640089 inhibits cell proliferation, cell viability and reduces AKT phosphorylation levels in SUM149 cells. ZINC00640089 has good potential for research in inflammatory breast cancer (IBC)

In Vitro

ZINC00640089 (0.01-100 µM; 72 h) reduces cell proliferation and cell viability in SUM149 cells. ZINC00640089 (1, 10 µM; 15 min, 1 h) reduces the p-Akt levels in SUM149 cells. MCE has not independently confirmed the accuracy of these methods. They are for reference only. Cell Viability AssayCell Line: SUM149 cells Concentration: 0.01-100 µM Incubation Time: 72 h Result: Reduced cell viability at concentrations of 1 µM or lower. Western Blot AnalysisCell Line: SUM149 cells Concentration: 1, 10 µM Incubation Time: 15 min, 1 h, 24 h Result: Reduced the p-Akt protein levels 15 min and 1 h and changes in the p-Akt protein levels were not observed at 24 h.

Form:Solid

IC50& Target:LCN2

Specifications

Specifications & Purity

≥99%

Biochemical and Physiological Mechanisms

ZINC00640089 is a specific Lipocalin-2 ( LCN2 ) inhibitor. ZINC00640089 inhibits cell proliferation, cell viability and reduces AKT phosphorylation levels in SUM149 cells. ZINC00640089 has good potential for research in inflammatory breast cancer (IBC) [1

Storage

Store at -20°C

Shipped In

Ice chest + Ice pads

This product requires cold chain shipping. Ground and other economy services are not available.

Purity

≥99%

Names and Identifiers

• Canonical Smiles: O=C(CN1C(C2=C3C1=CC=CC3=CC=C2)=O)NC4=C(C(F)(F)F)C=CC=C4
• Molecular Weight: 370.32

Chemical and Physical Properties

• Solubility: DMSO : ≥ 50 mg/mL (135.02 mM)