≥90% for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
Room temperature Ships Check lot-specific COA for exact specifications.
SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
1,2-Dibromoethane-1-sulfonyl fluoride (DESF) is a bench-stable precursor to 1-bromoethene-1-sulfonyl fluoride (BESF), a new and robust connective hub for the Sulfur (VI) fluoride exchange (SuFEx) click reaction. BESF offers similar routes as ethenesulfonyl fluoride (ESF, cat#746959) but with additional reactivity due to the embedded bromo group.Treatment of DESF with triethylamine generates BESF in situ, which has been used to synthesize diverse and unprecented sulfonyl fluorides in good-to-excellent yields. As the resulting molecules possess sulfonyl fluoride handles, further SuFEx reactions are also possible. DESF adds another useful tool for conjugation strategies in chemical biology and organic and polymer synthesis.
| Canonical Smiles | C(C(S(=O)(=O)F)Br)Br |
|---|---|
| IUPAC Name | 1,2-dibromoethanesulfonyl fluoride |
| InChIKey | NIJDNCLEFCJVRL-UHFFFAOYSA-N |
| INCHI | 1S/C2H3Br2FO2S/c3-1-2(4)8(5,6)7/h2H,1H2 |
| Isomeric SMILES | C(C(S(=O)(=O)F)Br)Br |
| Molecular Weight | 269.92 |
| Reaxy-Rn | 5495048 |
| Reaxys-RN_link_address | https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=5495048&ln= |
Comprehensive hazard, handling, storage, and regulatory compliance document.
Download SDS →Lot-specific quality data. Enter your lot number to retrieve the exact COA.
Look up COA →Full quality attributes and acceptance criteria for this grade.
View spec sheet →| Flash Point(°F) | Not applicable |
|---|---|
| Flash Point(°C) | Not applicable |
