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· · COA & SDS available for every product · Same-day shipping on in-stock items 1-(5-Iodonaphthalene-1-sulfonyl)-1H-hexahydro-1，4 -diazepine， Hydrochloride - ≥98% , CAS No.110448-33-4
Synonyms
A802196 | methoxy acetic acid chloride | 1-[(5-iodo-1-naphthalenyl)sulfonyl]-1,4-diazepane hydrochloride | FT-0605793 | 1-((5-Iodonaphthalen-1-yl)sulfonyl)-1,4-diazepane hydrochloride | J-002426 | EX-A2459 | s8388 | C15H17IN2O2S.HCl | CCG-36323 | 1-(5-iod
Shipped In
Ice chest + Ice pads
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Why this grade ≥98% for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
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Storage & shipping Store at -20°C Ships Ice chest + Ice pads Check lot-specific COA for exact specifications.
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Quality documents SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
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Literature proof Cited in 1 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
Specifications Synonyms
A802196 | methoxy acetic acid chloride | 1-[(5-iodo-1-naphthalenyl)sulfonyl]-1, 4-diazepane hydrochloride | FT-0605793 | 1-((5-Iodonaphthalen-1-yl)sulfonyl)-1, 4-diazepane hydrochloride | J-002426 | EX-A2459 | s8388 | C15H17IN2O2S.HCl | CCG-36323 | 1-(5-iod
Specifications & Purity
≥98%
Biochemical and Physiological Mechanisms
Selective MLCK inhibitor (Ki= 0.3μM). Exhibits more potent inhibition thanML 9 hydrochloride Displays reversible, ATP-competitive inhibition of Ca2+-calmodulin-dependent and -independent smooth muscle MLCKs. Inhibits proplatelet formation and stabilizatio
Shipped In
Ice chest + Ice pads
This product requires cold chain shipping. Ground and other economy services are not available.
Names and Identifiers Pubchem Sid 504764870 Pubchem Sid Url https://pubchem.ncbi.nlm.nih.gov/substance/504764870 Canonical Smiles C1CNCCN(C1)S(=O)(=O)C2=CC=CC3=C2C=CC=C3I.Cl IUPAC Name 1-(5-iodonaphthalen-1-yl)sulfonyl-1,4-diazepane;hydrochloride InChIKey KDDALCDYHZIZMH-UHFFFAOYSA-N INCHI 1S/C15H17IN2O2S.ClH/c16-14-6-1-5-13-12(14)4-2-7-15(13)21(19,20)18-10-3-8-17-9-11-18;/h1-2,4-7,17H,3,8-11H2;1H Isomeric SMILES C1CNCCN(C1)S(=O)(=O)C2=CC=CC3=C2C=CC=C3I.Cl WGK Germany 3 Alternate CAS 109376-83-2 Molecular Weight 452.74
Documentation 📋 Safety Data Sheet (SDS) Comprehensive hazard, handling, storage, and regulatory compliance document.
Download SDS → ✅ Certificate of Analysis (COA) Lot-specific quality data. Enter your lot number to retrieve the exact COA.
Look up COA → 📊 Datasheet Quick-reference summary of product specifications and applications.
View datasheet → 🔬 Specification Sheet Full quality attributes and acceptance criteria for this grade.
View spec sheet →
Advanced Data Taxonomic Classification Kingdom Organic compounds Superclass Benzenoids Class Naphthalenes Subclass Naphthalene sulfonic acids and derivatives Intermediate Tree Nodes Not available Direct Parent 1-naphthalene sulfonic acids and derivatives Alternative Parents 1-naphthalene sulfonamides 1,4-diazepanes Organosulfonamides Aryl iodides Sulfonyls Dialkylamines Azacyclic compounds Organopnictogen compounds Organoiodides Organic oxides Hydrochlorides Hydrocarbon derivatives Molecular Framework Aromatic heteropolycyclic compounds Substituents 1-naphthalene sulfonamide - Naphthalene sulfonamide - 1-naphthalene sulfonic acid or derivatives - 1,4-diazepane - Diazepane - Aryl halide - Aryl iodide - Organosulfonic acid amide - Organic sulfonic acid or derivatives - Organosulfonic acid or derivatives - Sulfonyl - Secondary amine - Secondary aliphatic amine - Azacycle - Organoheterocyclic compound - Hydrocarbon derivative - Amine - Organic nitrogen compound - Organosulfur compound - Organonitrogen compound - Organoiodide - Organohalogen compound - Organic oxide - Organopnictogen compound - Organic oxygen compound - Hydrochloride - Aromatic heteropolycyclic compound Description This compound belongs to the class of organic compounds known as 1-naphthalene sulfonic acids and derivatives. These are organic aromatic compounds that contain a naphthalene moiety that carries a sulfonic acid group (or a derivative thereof) at the 1-position. Naphthalene is a bicyclic compound that is made up of two fused benzene ring. External Descriptors Not available Data sources 1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.
3D Structure Associated Targets(Human) Associated Targets(non-human) Mechanisms of Action Certificates（CoA,COO,BSE/TSE and Analysis Chart) Chemical and Physical Properties Solubility Solvent:DMSO, Max Conc. mg/mL: 22.64, Max Conc. mM: 50 Molecular Weight 452.700 g/mol XLogP3 Hydrogen Bond Donor Count 2 Hydrogen Bond Acceptor Count 4 Rotatable Bond Count 2 Exact Mass 451.982 Da Monoisotopic Mass 451.982 Da Topological Polar Surface Area 57.800 Ų Heavy Atom Count 22 Formal Charge 0 Complexity 451.000 Isotope Atom Count 0 Defined Atom Stereocenter Count 0 Undefined Atom Stereocenter Count 0 Defined Bond Stereocenter Count 0 Undefined Bond Stereocenter Count 0 The total count of all stereochemical bonds 0 Covalently-Bonded Unit Count 2
Citations of This Product References 1. Jiansong Zhao, Tian Yin, Yaxin Deng, Hongbing Liu, Mingli Wei, Chenxiao Chu, Xinxin Liang, Xiaoshuang Bi, Haibing He, Jingxin Gou, Xing Tang, Yu Zhang. (2026) Harnessing semen-derived exosomes for noninvasive fundus drug delivery: A paradigm for exosome-based ocular fundus therapeutics. Science Advances, 12 (13): [PMID: [10.1126/sciadv.adw7275 ]
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