10-Deacetylbaccatin-III - 10mM in DMSO , CAS No.32981-86-5

CAS: 32981-86-5 Cat. No.: D407782 Molecular Weight: 544.59 EC Number: 608-810-1
AVAILABLE TO ORDER
GRADE & PURITY 10mM in DMSO
Synonyms
7,11-Methano-5H-cyclodeca[3,4]benz[1,2-b]oxet-5-one, 12b-(acetyloxy)-12-(benzoyloxy)-1,2a,3,4,4a,6,9,10,11,12,12a,12b-dodecahydro-4,6,9,11-tetrahydroxy-4a,8,13,13-tetramethyl-, (2aR,4S,4aS,6R,9S,11S,12S,12aR,12bS)-
Storage
Store at -80°C
Shipped In
Dry ice packs + Cold packs
 ·  off list, applied to all prices below.
Size
Status
Price
Qty
1ml
D407782-1ml
2

$548.90

$799.90
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Why this grade

10mM in DMSO for sensitive chromatographic and analytical workflows requiring minimal baseline interference.

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Storage & shipping

Store at -80°C Ships Dry ice packs + Cold packs Check lot-specific COA for exact specifications.

📋

Quality documents

SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.

📚

Literature proof

Cited in 7 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.

Overview

Information

10-Deacetylbaccatin-III is an antineoplastic agent and an anti-cancer intermediate.
In vitro


In vivo


Cell Data

cell lines:

Concentrations:

Incubation Time:

Powder Purity:≥99%

Specifications

Synonyms
7, 11-Methano-5H-cyclodeca[3, 4]benz[1, 2-b]oxet-5-one, 12b-(acetyloxy)-12-(benzoyloxy)-1, 2a, 3, 4, 4a, 6, 9, 10, 11, 12, 12a, 12b-dodecahydro-4, 6, 9, 11-tetrahydroxy-4a, 8, 13, 13-tetramethyl-, (2aR, 4S, 4aS, 6R, 9S, 11S, 12S, 12aR, 12bS)-
Specifications & Purity
10mM in DMSO
Biochemical and Physiological Mechanisms
10-Deacetylbaccatin-III is an antineoplastic agent and an anti-cancer intermediate.
Storage
Store at -80°C
Shipped In
Dry ice packs + Cold packs
This product requires cold chain shipping. Ground and other economy services are not available.
Names and Identifiers
Isomeric SMILES CC1=C2[C@H](C(=O)[C@@]3([C@H](C[C@@H]4[C@]([C@H]3[C@@H]([C@@](C2(C)C)(C[C@@H]1O)O)OC(=O)C5=CC=CC=C5)(CO4)OC(=O)C)O)C)O
WGK Germany 3
Molecular Weight 544.59
Reaxy-Rn 13170468
Reaxys-RN_link_address https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=13170468&ln=

Documentation

📋 Safety Data Sheet (SDS)

Comprehensive hazard, handling, storage, and regulatory compliance document.

Download SDS →

✅ Certificate of Analysis (COA)

Lot-specific quality data. Enter your lot number to retrieve the exact COA.

Look up COA →

📊 Datasheet

Quick-reference summary of product specifications and applications.

View datasheet →

🔬 Specification Sheet

Full quality attributes and acceptance criteria for this grade.

View spec sheet →

Advanced Data

Certificates(CoA,COO,BSE/TSE and Analysis Chart)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:
Chemical and Physical Properties
Specific Rotation[α]-42° (C=1,MeOH)
Melt Point(°C)231-236°C
Citations of This Product
References
1. Hao Li, Wenbo Xie, Lei Zeng, Wen Li, Boan Shi, Fuhou Lei.  (2022)  Development and evaluation of a hydrogenated rosin (β-acryloxyl ethyl) ester–bonded silica stationary phase for high-performance liquid chromatography separation of paclitaxel from yew bark.  JOURNAL OF CHROMATOGRAPHY A,      [PMID:35038614] [10.1016/j.chroma.2022.462815]
2. Jia Gao, Li Chen, Yongsheng Yan, Jian Lu, Wendong Xing, Jiangdong Dai, Minjia Meng, Yilin Wu.  (2021)  Dot-matrix-initiated molecularly imprinted nanocomposite membranes for selective recognition: a high-efficiency separation system with an anti-oil fouling layer.  Environmental Science-Nano,  (10): (2932-2949).  [PMID:] [10.1039/D1EN00296A]
3. Bi Wang, Shu Xu, Yan Cao, Fei Liu, Xingzeng Zhao, Xu Feng.  (2018)  Fungicidal activity of 10-deacetylbacatin III against Phytophthora capsici via inhibiting lysine biosynthesis.  PESTICIDE BIOCHEMISTRY AND PHYSIOLOGY,      [PMID:30497701] [10.1016/j.pestbp.2018.09.008]
4. Yu Chunna, Luo Xiujun, Zhan Xiaori, Hao Juan, Zhang Lei, L Song Yao-Bin, Shen Chenjia, Dong Ming.  (2018)  Comparative metabolomics reveals the metabolic variations between two endangered Taxus species (T. fuana and T. yunnanensis) in the Himalayas.  BMC PLANT BIOLOGY,  18  (1): (1-12).  [PMID:30223770] [10.1186/s12870-018-1412-4]
5. Hao Juan, Guo Hong, Shi Xinai, Wang Ye, Wan Qinghua, Song Yao-Bin, Zhang Lei, Dong Ming, Shen Chenjia.  (2017)  Comparative proteomic analyses of two Taxus species (Taxus × media and Taxus mairei) reveals variations in the metabolisms associated with paclitaxel and other metabolites.  PLANT AND CELL PHYSIOLOGY,  58  (11): (1878-1890).  [PMID:29016978] [10.1093/pcp/pcx128]
6. Yu Chunna, Guo Hong, Zhang Yangyang, Song Yaobin, Pi Erxu, Yu Chenliang, Zhang Lei, Dong Ming, Zheng Bingsong, Wang Huizhong, Shen Chenjia.  (2017)  Identification of potential genes that contributed to the variation in the taxoid contents between two Taxus species (Taxus media and Taxus mairei).  TREE PHYSIOLOGY,  37  (12): (1659-1671).  [PMID:28985439] [10.1093/treephys/tpx091]
7. Na Yang, Xingyuan Zhang, Juanqiong Ma, Liqing Ouyang, Zhiyong Xie, Pei Li, Xiao Lin, Qiongfeng Liao, Yanlong Chen.  (2025)  Synergistic integration of three-dimensional covalent organic frameworks and molecularly imprinted nanocavities for selective extraction of chiral 10-deacetylbacatin III.  JOURNAL OF CHROMATOGRAPHY A,      [PMID:40440919] [10.1016/j.chroma.2025.466072]
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