≥97% for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
Room temperature Ships Normal Check lot-specific COA for exact specifications.
SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
Cited in 1 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
2-Chlorobenzimidazole can be synthesized by reacting benzimidazole-2-one with phosphoryl chloride in the presence of phenol；
Application：
2-Chlorobenzimidazole can be used to synthesize the following:
1-methyl-2-chlorobenzimidazole via reaction with dimethyl sulfate；
1-ethyl-2-chlorobenzimidazole via reaction with diethyl sulfate；
1-benzyl-2-chlorobenzimidazole via reaction with benzyl chloride；
2-chloro-4,5,6,7-tetrabromobenzimidazole via bromination with bromine；
It may be used as a building block to synthesize 4-amino-6-benzimidazole-pyrimidines；
| Pubchem Sid | 488185597 |
|---|---|
| Pubchem Sid Url | https://pubchem.ncbi.nlm.nih.gov/substance/488185597 |
| Canonical Smiles | C1=CC=C2C(=C1)NC(=N2)Cl |
| IUPAC Name | 2-chloro-1H-benzimidazole |
| InChIKey | AYPSHJCKSDNETA-UHFFFAOYSA-N |
| INCHI | 1S/C7H5ClN2/c8-7-9-5-3-1-2-4-6(5)10-7/h1-4H,(H,9,10) |
| Isomeric SMILES | C1=CC=C2C(=C1)NC(=N2)Cl |
| Molecular Weight | 152.58 |
| Beilstein | 23(5)6,264 |
| Reaxy-Rn | 116526 |
| Reaxys-RN_link_address | https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=116526&ln= |
Comprehensive hazard, handling, storage, and regulatory compliance document.
Download SDS →Lot-specific quality data. Enter your lot number to retrieve the exact COA.
Look up COA →Full quality attributes and acceptance criteria for this grade.
View spec sheet →Taxonomy Tree
| Kingdom | Organic compounds |
|---|---|
| Superclass | Organoheterocyclic compounds |
| Class | Benzimidazoles |
| Subclass | Not available |
| Intermediate Tree Nodes | Not available |
| Direct Parent | Benzimidazoles |
| Alternative Parents | Benzenoids Aryl chlorides Imidazoles Heteroaromatic compounds Azacyclic compounds Organopnictogen compounds Organonitrogen compounds Organochlorides Hydrocarbon derivatives |
| Molecular Framework | Aromatic heteropolycyclic compounds |
| Substituents | Benzimidazole - Benzenoid - Aryl halide - Aryl chloride - Heteroaromatic compound - Imidazole - Azole - Azacycle - Organic nitrogen compound - Organopnictogen compound - Hydrocarbon derivative - Organonitrogen compound - Organochloride - Organohalogen compound - Aromatic heteropolycyclic compound |
| Description | This compound belongs to the class of organic compounds known as benzimidazoles. These are organic compounds containing a benzene ring fused to an imidazole ring (five member ring containing a nitrogen atom, 4 carbon atoms, and two double bonds). |
| External Descriptors | Not available |
Find and download the COA for your product by matching the lot number on the packaging.
| Lot Number | Certificate Type | Date | Item |
|---|---|---|---|
 C1911205 | Certificate of Analysis | May 21, 2026 | C137611 |
| H2303399 | Certificate of Analysis | May 12, 2025 | C137611 |
| H2303404 | Certificate of Analysis | May 12, 2025 | C137611 |
| H2303417 | Certificate of Analysis | May 12, 2025 | C137611 |
| H2303486 | Certificate of Analysis | May 12, 2025 | C137611 |
| B2508435 | Certificate of Analysis | Mar 23, 2024 | C137611 |
| K2119524 | Certificate of Analysis | Sep 15, 2023 | C137611 |
| K2119540 | Certificate of Analysis | Sep 15, 2023 | C137611 |
| B1922065 | Certificate of Analysis | Sep 20, 2022 | C137611 |
| F23081104 | Certificate of Analysis | Jul 29, 2021 | C137611 |
| Solubility | Insoluble in water |
|---|---|
| Melt Point(°C) | 207-211 °C (lit.) |
| Molecular Weight | 152.580 g/mol |
| XLogP3 | 2.200 |
| Hydrogen Bond Donor Count | 1 |
| Hydrogen Bond Acceptor Count | 1 |
| Rotatable Bond Count | 0 |
| Exact Mass | 152.014 Da |
| Monoisotopic Mass | 152.014 Da |
| Topological Polar Surface Area | 28.700 Ų |
| Heavy Atom Count | 10 |
| Formal Charge | 0 |
| Complexity | 129.000 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 0 |
| Undefined Atom Stereocenter Count | 0 |
| Defined Bond Stereocenter Count | 0 |
| Undefined Bond Stereocenter Count | 0 |
| The total count of all stereochemical bonds | 0 |
| Covalently-Bonded Unit Count | 1 |
| 1. Rong-Kuan Jiang, Yue Pan, Li-Hua Du, Ling-Yan Zheng, Zhi-Kai Sheng, Shi-Yi Zhang, Hang Lin, Ao-Ying Zhang, Han-Jia Xie, Zhi-Kai Yang, Xi-Ping Luo. (2022) Microfluidics Biocatalysis System Applied for the Synthesis of N-Substituted Benzimidazole Derivatives by Aza-Michael Addition. Catalysts, 12 (12): (1658). [PMID:] [10.3390/catal12121658] |
