3,3-Dimethyl-1-butanol - Moligand™, 10 mM in DMSO , CAS No.624-95-3

CAS: 624-95-3 Cat. No.: D1500450 Molecular Weight: 102.17 Beilstein Registry Number: 1731466 EC Number: 210-872-6

GRADE & PURITY Moligand™, 10 mM in DMSO

Storage

Store at -80°C

Shipped In

Dry ice packs + Cold packs

Overview

3,3-Dimethyl-1-butanol (DMB) is an orally active inhibitor of trimethylamine ( TMA ) and trimethylamine N-oxide ( TMAO ). 3,3-Dimethyl-1-butanol inhibits the signaling pathway of p65 NF-κB and TGF-β1/Smad3 . 3,3-Dimethyl-1-butanol has potential applications in cardiovascular disease (CVD).

Specifications

Specifications & Purity

Moligand™, 10 mM in DMSO

Storage

Store at -80°C

Shipped In

Dry ice packs + Cold packs

This product requires cold chain shipping. Ground and other economy services are not available.

Grade

Moligand™

Names and Identifiers

• Isomeric SMILES: CC(C)(C)CCO
• WGK Germany: 3
• UN Number: 1987
• Packing Group: III
• Molecular Weight: 102.17
• Beilstein: 1731466
• Reaxy-Rn: 1731466
• Reaxys-RN_link_address: https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=1731466&ln=

Chemical and Physical Properties

• Refractive Index: 1.414
• Flash Point(°F): 133 °F
• Flash Point(°C): 56°C
• Boil Point(°C): 142-143℃
• Melt Point(°C): -60℃

References

1. Yang Xiaomei, Fu Xiaomin, Bu Ningning, Han Li, Wang Jianfeng, Song Chengying, Su Yunlai, Zhou Lipeng, Lu Tianliang.  (2016)  Promotion effect of nickel for Cu–Ni/γ-Al2O3 catalysts in the transfer dehydrogenation of primary aliphatic alcohols.  Journal of the Iranian Chemical Society,  14  (1): (111-119).  [PMID:] [10.1007/s13738-016-0963-2]

2. Q Chen, Z Qiu, Y Zhao, L Bai, Y Chan, S Jin, F Ma, J Dai.  (2026)  TMAO Induced Kidney Aging by Activating ZBP1-Mediated Necroptosis.  PHYSIOLOGICAL RESEARCH,      [PMID:41811704] [PMID:41811704]