≥97% for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
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Storage & shipping
Store at 2-8°C,Protected from light,Argon charged Ships Wet ice Check lot-specific COA for exact specifications.
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Quality documents
SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
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Literature proof
Cited in 3 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
Overview
Excitotoxin shown to cause brain lesions similar to those of Huntington′s disease.3-Nitropropionic acid (β-Nitropropionic Acid, 3-NP) is an irreversible inhibitor of mitochondrial respiratory Complex II succinate dehydrogenase, resulting in energy depletion through disruption of the electron transport chain.
3-Nitropropionic acid is a potent irreversible inhibitor of mitochondrial complex II enzyme, which causes dysfunction and oxidative stress in mitochondria. 3-Nitropropionic acid is an important research compound because it can simulate the effects on cell
Storage
Store at 2-8°C, Protected from light, Argon charged
Shipped In
Wet ice
This product requires cold chain shipping. Ground and other economy services are not available.
Action Type
INHIBITOR
Note
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Toxic, refer to SDS for further information. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
This compound belongs to the class of organic compounds known as c-nitro compounds. These are compounds having the nitro group, -NO2 (free valence on nitrogen), which is attached to carbon.
External Descriptors
C-nitro compound
1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.
1.Shanshan Wang, Qifeng Li, Fanghui Wang. (2020) The effect of imidazolated PPO with different alkyl chains on its performance as a high temperature proton exchange membrane. Polymer-Plastics Technology and Materials, [PMID:][10.1080/25740881.2020.1750650]
2.Suxia Wang, Min Zhou, Yongxi Zhu, Bo Peng, Jia Yang, Yongjun Ma. (2020) Voltammetric Detection of 3-Nitropropionic Acid in Sugarcane Juices Using a Poly(L-citrulline)/Lanthanide-Containing Cyano-Bridged Heterometallic Coordination Polymer Modified Electrode. JOURNAL OF THE ELECTROCHEMICAL SOCIETY, 167 (8):(086508). [PMID:][10.1149/1945-7111/ab8ece]
3.Liwei Gao, Dingfeng Wang, Siting Peng, Wendi Xiao, Xinru Liu, Houwen Hu, Ting Zhang, Xuan Leng, Da Chen. (2025) An efficient and fast strategy for the ratiometric detection and differentiation of nitrophenols using triple-excited carbon dots under neutral conditions. FOOD CHEMISTRY, [PMID:41016162][10.1016/j.foodchem.2025.146535]
Solution Calculators
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