6-Methylflavone - Moligand™, ≥98% , Antagonist of TAS2R39, CAS No.29976-75-8, Antagonist of TAS2R39

CAS: 29976-75-8 Cat. No.: M157945 Formule: C16H12O2 Poids moléculaire: 236.27
DISPONIBLE À COMMANDE
GRADE & PURITY Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
Synonyms
6-Methylflavone | K3JCS9D3KJ | CCG-250475 | FT-0638897 | 6-Methyl-2-phenyl-4H-1-benzopyran-4-one | BIDD:ER0442 | NCGC00142612-01 | Q63398074 | ST069348 | SCHEMBL4648879 | HMS1440M05 | Cambridge id 5479507 | UNII-K3JCS9D3KJ | PD078581 | MFCD00017461 | HY-N
Storage
Store at 2-8°C
Shipped In
Wet ice
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Size
Allemagne (EU)
USA*
Price
Qty
250mg
M157945-250mg
—
3 En stock

13,80€

20,74€
Enregistrer 6,94 € (33.47%)
1g
M157945-1g
—
2 En stock

53,71€

80,61€
Enregistrer 26,90 € (33.37%)
5g
M157945-5g
—
3 En stock

232,47€

348,74€
Enregistrer 116,28 € (33.34%)
Enter a quantity for the sizes you want to add.
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Why this grade

Moligand™, ≥98% Moligand™ for sensitive chromatographic and analytical workflows requiring minimal baseline interference.

🌡

Storage & shipping

Store at 2-8°C Ships Wet ice Check lot-specific COA for exact specifications.

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Quality documents

SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.

📚

Literature proof

Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.

Specifications

Synonymes
6-Methylflavone | K3JCS9D3KJ | CCG-250475 | FT-0638897 | 6-Methyl-2-phenyl-4H-1-benzopyran-4-one | BIDD:ER0442 | NCGC00142612-01 | Q63398074 | ST069348 | SCHEMBL4648879 | HMS1440M05 | Cambridge id 5479507 | UNII-K3JCS9D3KJ | PD078581 | MFCD00017461 | HY-N
Spécifications et pureté
Moligand™, ≥98%
Mécanismes biochimiques et physiologiques
6-Methylflavone is a bitter taste blocker that significantly reduces bitter test of HIV drug tenofovir alafenamide in human subjects. 6-Methylflavone is a selective and potent modulator of TAS2R39 bitter test receptor that blocks it response to tenofovir
Conditions de stockage de stockage
Store at 2-8°C
Expédié en
Wet ice
Ce produit nécessite l'expédition en chaîne froide. Les services terrestres et autres services économiques ne sont pas disponibles.
Grade
Moligand™
Type d'action
ANTAGONIST
Mécanisme d'action
Antagonist of TAS2R39
Pureté
≥98%
Noms et identifiants
Pubchem Sid
Pubchem Sid Url
https://pubchem.ncbi.nlm.nih.gov/substance/504759902
Sourires canoniques
CC1=CC2=C(C=C1)OC(=CC2=O)C3=CC=CC=C3
IUPAC Name
6-methyl-2-phenylchromen-4-one
InChIKey
NOQJBXPAMJLUSS-UHFFFAOYSA-N
INCHI
1S/C16H12O2/c1-11-7-8-15-13(9-11)14(17)10-16(18-15)12-5-3-2-4-6-12/h2-10H,1H3
Isomères SMILES
CC1=CC2=C(C=C1)OC(=CC2=O)C3=CC=CC=C3
Poids moléculaire
236.27
Reaxy-Rn
179812
Reaxys-RN_link_address
https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=179812&ln=

Documentation

📋 Safety Data Sheet (SDS)

Comprehensive hazard, handling, storage, and regulatory compliance document.

Download SDS →

✅ Certificate of Analysis (COA)

Lot-specific quality data. Enter your lot number to retrieve the exact COA.

Look up COA →

📊 Datasheet

Quick-reference summary of product specifications and applications.

View datasheet →

🔬 Specification Sheet

Full quality attributes and acceptance criteria for this grade.

View spec sheet →

Advanced Data

Taxonomic Classification

Taxonomy Tree

KingdomOrganic compounds
SuperclassPhenylpropanoids and polyketides
ClasseFlavonoids
SubclassFlavones
Intermediate Tree Nodes Not available
Direct ParentFlavones
Alternative Parents Chromones  Pyranones and derivatives  Benzene and substituted derivatives  Heteroaromatic compounds  Oxacyclic compounds  Organooxygen compounds  Organic oxides  Hydrocarbon derivatives  
Molecular FrameworkAromatic heteropolycyclic compounds
Substituents Flavone - Chromone - Benzopyran - 1-benzopyran - Pyranone - Benzenoid - Monocyclic benzene moiety - Pyran - Heteroaromatic compound - Oxacycle - Organoheterocyclic compound - Organooxygen compound - Organic oxide - Organic oxygen compound - Hydrocarbon derivative - Aromatic heteropolycyclic compound
DescriptionThis compound belongs to the class of organic compounds known as flavones. These are flavonoids with a structure based on the backbone of 2-phenylchromen-4-one (2-phenyl-1-benzopyran-4-one).
External Descriptors Not available
Structure 3D
Modèle de structure chimique interactif





Cibles associées (humaines)
TAS2R39 Tchem Taste receptor type 2 member 39 (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
NR3C1 Tclin Glucocorticoid receptor (14987 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
AR Tclin Androgen Receptor (11781 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
AHR Tclin Aryl hydrocarbon receptor (1071 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
ALDH1A1 Tchem Aldehyde dehydrogenase 1A1 (77053 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CYP3A4 Tclin Cytochrome P450 3A4 (53859 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
TP53 Tchem Cellular tumor antigen p53 (48468 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
HepG2 (196354 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
SMMC-7721 (5516 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
HSD17B10 Tchem Endoplasmic reticulum-associated amyloid beta-peptide-binding protein (20669 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
TNKS Tchem Tankyrase-1 (1241 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
KDM4E Tchem Lysine-specific demethylase 4D-like (40243 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
HPGD Tchem 15-hydroxyprostaglandin dehydrogenase [NAD+] (24926 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Cibles associées (non humaines)
Spodoptera frugiperda (784 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
RAW264.7 (28094 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Spodoptera litura (1708 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Mapt Microtubule-associated protein tau (6 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Rorc Nuclear receptor ROR-gamma (89407 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Mécanismes d'action
Certificats (CoA, COO, BSE/TSE et tableau d'analyse)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

6 results found

Lot NumberCertificate TypeDateArticle
H23031107Certificate of AnalysisJul 14, 2023 M157945
H23031108Certificate of AnalysisJul 14, 2023 M157945
H23031115Certificate of AnalysisJul 14, 2023 M157945
H23031123Certificate of AnalysisJul 14, 2023 M157945
H23031124Certificate of AnalysisJul 14, 2023 M157945
H23031137Certificate of AnalysisJul 14, 2023 M157945
Propriétés chimiques et physiques
SolubilitéSoluble in Methanol
Point d'ébullition (°C)235°C/12mmHg(lit.)
Point de fusion (°C)121 °C
Poids moléculaire236.260 g/mol
XLogP33.900
Hydrogen Bond Donor Count0
Hydrogen Bond Acceptor Count2
Rotatable Bond Count1
Exact Mass236.084 Da
Monoisotopic Mass236.084 Da
Topological Polar Surface Area26.300 Ų
Heavy Atom Count18
Formal Charge0
Complexity352.000
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
The total count of all stereochemical bonds0
Covalently-Bonded Unit Count1
Calculateurs de solution
Avis

Avis des clients

Foire aux questions

What is the purity of this product?
This product is supplied at ≥98% purity (chemical assay). Lot-specific values are stated on the Certificate of Analysis.
What is Moligand??
Moligand? is one of Aladdin Scientific's premium product lines, formulated for high-purity applications across multiple workflows. Compared to standard grades in the same workflow, Moligand? products typically offer tighter specifications, more rigorous QC, and stronger lot-to-lot consistency.
How should this product be stored?
Store at 2–8 °C. Refrigerated storage is required to maintain the specified shelf life.
How is this product shipped?
This product ships chilled on wet ice. Unpack on arrival and transfer it to the storage condition stated above.
What are the CAS number, molecular formula and molecular weight?
The CAS Number is 29976-75-8, the molecular formula is C16H12O2, and the molecular weight is 236.27 g/mol. InChIKey NOQJBXPAMJLUSS-UHFFFAOYSA-N.
What documentation is provided?
Available product documentation, including Certificates of Analysis (COA), Safety Data Sheets (SDS), and specification sheets, is shown in the product document area. Document availability and access follow the current site policy.

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