≥98% for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
Store at 2-8°C,Argon charged,Desiccated Ships Wet ice Check lot-specific COA for exact specifications.
SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
A very potent, water-soluble antagonist of the NMDA receptors complex acting at the strychnine-insensitive glycine binding site (IC50 = 0.56 µM). Also a potent inhibitor of glutamate transporter. Often used in studies of neuroprotection and schizophrenia.
Product Application
7-Chlorokynurenic acid sodium salt is used as a Potent competitive inhibitor of L-glutamate transport into synaptic vesicles. It is also used as an NMDA receptor antagonist and inhibitor of EAAT.
| Canonical Smiles | C1=CC2=C(C=C1Cl)NC(=CC2=O)C(=O)[O-].[Na+] |
|---|---|
| IUPAC Name | sodium;7-chloro-4-oxo-1H-quinoline-2-carboxylate |
| InChIKey | IFZYIORLNGNLEI-UHFFFAOYSA-M |
| INCHI | 1S/C10H6ClNO3.Na/c11-5-1-2-6-7(3-5)12-8(10(14)15)4-9(6)13;/h1-4H,(H,12,13)(H,14,15);/q;+1/p-1 |
| Isomeric SMILES | C1=CC2=C(C=C1Cl)NC(=CC2=O)C(=O)[O-].[Na+] |
| PubChem CID | 52974249 |
| Molecular Weight | 245.59 |
Comprehensive hazard, handling, storage, and regulatory compliance document.
Download SDS →Lot-specific quality data. Enter your lot number to retrieve the exact COA.
Look up COA →Full quality attributes and acceptance criteria for this grade.
View spec sheet →Taxonomy Tree
| Kingdom | Organic compounds |
|---|---|
| Superclass | Organoheterocyclic compounds |
| Class | Quinolines and derivatives |
| Subclass | Quinoline carboxylic acids |
| Intermediate Tree Nodes | Not available |
| Direct Parent | Quinoline carboxylic acids |
| Alternative Parents | Chloroquinolines Hydroquinolones Hydroquinolines Pyridinecarboxylic acids Aryl chlorides Benzenoids Vinylogous amides Heteroaromatic compounds Carboxylic acid salts Azacyclic compounds Carboxylic acids Organic metal halides Organopnictogen compounds Hydrocarbon derivatives Organic oxides Organic sodium salts Organochlorides Organonitrogen compounds Organooxygen compounds Organic cations |
| Molecular Framework | Aromatic heteropolycyclic compounds |
| Substituents | Quinoline-2-carboxylic acid - Haloquinoline - Dihydroquinolone - Chloroquinoline - Dihydroquinoline - Pyridine carboxylic acid or derivatives - Pyridine carboxylic acid - Aryl chloride - Aryl halide - Pyridine - Benzenoid - Heteroaromatic compound - Vinylogous amide - Carboxylic acid salt - Azacycle - Carboxylic acid - Carboxylic acid derivative - Organic metal halide - Organic alkali metal salt - Organic nitrogen compound - Organic oxygen compound - Organooxygen compound - Organonitrogen compound - Organochloride - Organohalogen compound - Organic salt - Organic sodium salt - Hydrocarbon derivative - Organic oxide - Organopnictogen compound - Organic cation - Aromatic heteropolycyclic compound |
| Description | This compound belongs to the class of organic compounds known as quinoline carboxylic acids. These are quinolines in which the quinoline ring system is substituted by a carboxyl group at one or more positions. |
| External Descriptors | Not available |
Find and download the COA for your product by matching the lot number on the packaging.
| Lot Number | Certificate Type | Date | Item |
|---|---|---|---|
 F2503223 | Certificate of Analysis | Jun 11, 2025 | C288151 |
| F2503224 | Certificate of Analysis | Jun 11, 2025 | C288151 |
| F2503257 | Certificate of Analysis | Jun 11, 2025 | C288151 |
| F2503258 | Certificate of Analysis | Jun 11, 2025 | C288151 |
| F2503259 | Certificate of Analysis | Jun 11, 2025 | C288151 |
| F2503260 | Certificate of Analysis | Jun 11, 2025 | C288151 |
| F2503261 | Certificate of Analysis | Jun 11, 2025 | C288151 |
| F2503262 | Certificate of Analysis | Jun 11, 2025 | C288151 |
| F2503263 | Certificate of Analysis | Jun 11, 2025 | C288151 |
| F2503264 | Certificate of Analysis | Jun 11, 2025 | C288151 |
| Solubility | Solvent:water, Max Conc. mg/mL: 24.56, Max Conc. mM: 100 |
|---|---|
| Molecular Weight | 245.590 g/mol |
| XLogP3 | |
| Hydrogen Bond Donor Count | 1 |
| Hydrogen Bond Acceptor Count | 4 |
| Rotatable Bond Count | 1 |
| Exact Mass | 244.986 Da |
| Monoisotopic Mass | 244.986 Da |
| Topological Polar Surface Area | 69.200 Ų |
| Heavy Atom Count | 16 |
| Formal Charge | 0 |
| Complexity | 345.000 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 0 |
| Undefined Atom Stereocenter Count | 0 |
| Defined Bond Stereocenter Count | 0 |
| Undefined Bond Stereocenter Count | 0 |
| The total count of all stereochemical bonds | 0 |
| Covalently-Bonded Unit Count | 2 |
