5-Formyl-2-furanboronic acid(contains varying amounts of Anhydride) - ≥97% , CAS No.27329-70-0

CAS: 27329-70-0 Cat. No.: F100749 Molecular Weight: 139.9 Beilstein Registry Number: 18(5)12,589 EC Number: 628-001-7

GRADE & PURITY ≥97%

Synonyms

BCP22987 | AKOS000320207 | TD8089 | 5-Formylfuran-2-boronicacid | A5315 | (5-formylfuran-2Y1)boronic acid | J-517570 | 2-Formyl-5-furanylboronic acid | (5-formylfuran-2yl)boronic acid | (5-formylfuran-2-yl)boronic acid | SY007281 | (5-formyl-2-furyl)boron

Storage

Store at 2-8°C,Argon charged

Shipped In

Wet ice

Overview

Reactant involved in Suzuki coupling for synthesis of stable dye-senstitized solar cells

Reactant involved in synthesis of biologically active molecules including:

• Heteroarylation for the synthesis of HIF-1 inhibitors

• Disalicylic acid-furanyl derivatives to inhibit ephrin binding

• HIV-1 integrase inhibitors

• Epidermal growth factor receptor inhibitors

Specifications

Synonyms

BCP22987 | AKOS000320207 | TD8089 | 5-Formylfuran-2-boronicacid | A5315 | (5-formylfuran-2Y1)boronic acid | J-517570 | 2-Formyl-5-furanylboronic acid | (5-formylfuran-2yl)boronic acid | (5-formylfuran-2-yl)boronic acid | SY007281 | (5-formyl-2-furyl)boron

Specifications & Purity

≥97%

Storage

Store at 2-8°C, Argon charged

Shipped In

Wet ice

This product requires cold chain shipping. Ground and other economy services are not available.

Purity

≥97%

Names and Identifiers

• Canonical Smiles: B(C1=CC=C(O1)C=O)(O)O
• IUPAC Name: (5-formylfuran-2-yl)boronic acid
• InChIKey: JUWYQISLQJRRNT-UHFFFAOYSA-N
• INCHI: 1S/C5H5BO4/c7-3-4-1-2-5(10-4)6(8)9/h1-3,8-9H
• Isomeric SMILES: B(C1=CC=C(O1)C=O)(O)O
• WGK Germany: 3
• Alternate CAS: 27329-70-0
• UN Number: 3261
• Molecular Weight: 139.9
• Beilstein: 18(5)12,589
• Reaxy-Rn: 1637050
• Reaxys-RN_link_address: https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=1637050&ln=

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Organic oxygen compounds
    • Class Organooxygen compounds
      • Subclass Carbonyl compounds
        • Level5 Aldehydes
          • Level6 Aryl-aldehydes

• Kingdom: Organic compounds
• Superclass: Organic oxygen compounds
• Class: Organooxygen compounds
• Subclass: Carbonyl compounds
• Intermediate Tree Nodes: Aldehydes
• Direct Parent: Aryl-aldehydes
• Alternative Parents: Heteroaromatic compounds Furans Boronic acids Oxacyclic compounds Organic metalloid salts Organoboron compounds Organic oxides Hydrocarbon derivatives
• Molecular Framework: Aromatic heteromonocyclic compounds
• Substituents: Aryl-aldehyde - Heteroaromatic compound - Furan - Boronic acid - Boronic acid derivative - Oxacycle - Organic metalloid salt - Organoheterocyclic compound - Organic oxide - Hydrocarbon derivative - Organic salt - Organoboron compound - Aromatic heteromonocyclic compound
• Description: This compound belongs to the class of organic compounds known as aryl-aldehydes. These are compounds containing an aldehyde group directly attached to an aromatic ring.
• External Descriptors: Not available

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

Chemical and Physical Properties

• Solubility: Insoluble in water.
• Sensitivity: Air sensitive.
• Melt Point(°C): 136°C
• Molecular Weight: 139.900 g/mol
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 2
• Exact Mass: 140.028 Da
• Monoisotopic Mass: 140.028 Da
• Topological Polar Surface Area: 70.700 Ų
• Heavy Atom Count: 10
• Formal Charge: 0
• Complexity: 127.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 0
• Undefined Atom Stereocenter Count: 0
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 1

XLogP3

References

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2. Zhaomin Wang, Congcong Wang, Tianhe Fang, Yong Liu.  (2022)  Constructing a novel near-infrared fluorescent probe with a large Stokes shift for detection of RNA in the cancer cells.  DYES AND PIGMENTS,      [PMID:] [10.1016/j.dyepig.2022.110126]

3. Fei Zhang, Zhe Li, Yaoming Liu, Binsheng Yang, Hui Qiao, Jie Chai, Guangming Wen, Bin Liu.  (2020)  Rational construction of AIEgens with wide color tunability and their specific lipid droplet imaging applications.  Journal of Materials Chemistry B,  8  (41): (9533-9543).  [PMID:33000854] [10.1039/D0TB01806F]

4. Fei Zhang, Yaoming Liu, Binsheng Yang, Guangming Wen, Bin Liu.  (2020)  Near-infrared AIEgens for lipid droplets imaging in corpus adiposum or trachea of Locusta migratoria and its application in photodynamic therapy.  SENSORS AND ACTUATORS B-CHEMICAL,      [PMID:] [10.1016/j.snb.2020.128589]

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6. Chen Pu, Shan Guogang, Nie Qingli, Yan Yuting, Zhang Pengfei, Zhao Zujin, Feng Hai-Tao, Tang Ben Zhong.  (2024)  Two-color emissive AIEgens with anti-Kasha property for dual-organelle imaging and phototherapy.  Science China-Chemistry,      [PMID:] [10.1007/s11426-023-1903-1]

7. Yan Lei, Chengqi Feng, Jinhang Yang, Chenkai Jin, Yifei Huang, Juncheng Huang, Haining Na, Jin Zhu.  (2025)  Dual Capable Solid Acid for Fabricating Refinement-Free Fermentable Sugars in Cellulose Hydrolysis.  ACS Sustainable Chemistry & Engineering,      [PMID:] [10.1021/acssuschemeng.5c04594]

8. Juan Cai, Tianyu Wang, Chengqi Feng, yuxin zhu, Yan Lei, Jian Luo, Haining Na, Wei Li, Meina Huang, Jin Zhu.  (2026)  Oligosaccharide toughened polyacrylamide hydrogel for high sensitivity strain sensor.  Journal of Materials Chemistry C,      [PMID:] [10.1039/D6TC00109B]