Bisoprolol fumarate - 10mM in DMSO , Beta-1 adrenergic receptor antagonist, CAS No.104344-23-2, Beta-1 adrenergic receptor antagonist

CAS: 104344-23-2 Cat. No.: B409006 Molecular Weight: 383.48 EC Number: 600-557-5 PubChem CID: 5281064

GRADE & PURITY 10mM in DMSO

Synonyms

EMD33512 | 1-​[4-​[[2-​(1-​methylethoxy)​ethoxy]​methyl]​phenoxy]​-​3-​[(1-​methylethyl)​amino]​-2-​propanol,(2E)​-​2-​butenedioate (2:1)

Storage

Store at -80°C

Shipped In

Dry ice packs + Cold packs

Overview

Information

Bisoprolol fumarate (EMD33512) is a selective type β1 adrenergic receptor blocker.
In vitro

In vivo

Cell Data

cell lines：MCF-7, HCT-116, A549, and IM-9

Concentrations：

Incubation Time：

Powder Purity:≥99%

Specifications

Synonyms

EMD33512 | 1-​[4-​[[2-​(1-​methylethoxy)​ethoxy]​methyl]​phenoxy]​-​3-​[(1-​methylethyl)​amino]​-2-​propanol, (2E)​-​2-​butenedioate (2:1)

Specifications & Purity

10mM in DMSO

Biochemical and Physiological Mechanisms

Bisoprolol fumarate (EMD33512) is a selective type β1 adrenergic receptor blocker.

Storage

Store at -80°C

Shipped In

Dry ice packs + Cold packs

This product requires cold chain shipping. Ground and other economy services are not available.

Action Type

ANTAGONIST

Mechanism of action

Beta-1 adrenergic receptor antagonist

Names and Identifiers

• Isomeric SMILES: CC(C)NCC(COC1=CC=C(C=C1)COCCOC(C)C)O.CC(C)NCC(COC1=CC=C(C=C1)COCCOC(C)C)O.C(=C/C(=O)O)\C(=O)O
• WGK Germany: 3
• RTECS: UB8390000
• PubChem CID: 5281064
• Molecular Weight: 383.48

Chemical and Physical Properties

• Solubility: Solubility (25°C) In vitro DMSO: 33 mg/mL (200.97 mM); Water: Insoluble; Ethanol: 33 mg/mL

References

1. Qinghao Cao, Chao Chen, Jun Huang, Dantong Shen, Haolin Chen, Huiqing Zhong, Zhiming Liu, Zhouyi Guo.  (2022)  Mussel-inspired hydrogels for fast fabrication of flexible SERS tape for point-of-care testing of β-blockers.  ANALYST,  147  (16): (3652-3661).  [PMID:35839093] [10.1039/D2AN00688J]