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Coptisine Sulfate - ≥99% , CAS No.1198398-71-8

CAS: 1198398-71-8 Cat. No.: C651534 Molecular Weight: 320.3 PubChem CID: 72322
COA
Coptisine Sulfate - ≥99% CAS No(1198398-71-8) by Aladdin Scientific
AVAILABLE TO ORDER
GRADE & PURITY ≥99%
Synonyms
6,7-Dihydro[1,3]dioxolo[4,5-G][1,3]dioxolo[7,8]isoquino[3,2-A]isoquinolin-5-Ium | 3-Hydroxy-3-methylbutene | 1198398-71-8 | Bis(1,3)benzodioxolo(5,6-a:4',5'-g)quinolizinium, 6,7-dihydro- | Q5169053 | DTXCID00110895 | 6,7-Dihydrobis[1,3]benzodioxolo[5,6-a:
Storage
Store at 2-8°C,Protected from light,Desiccated
Shipped In
Wet ice
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 ·  off list, applied to all prices below.
Size
Status
Price
Qty
1mg
C651534-1mg
8-12 wks(?) Production requires sourcing of materials. We appreciate your patience and understanding.
$60.90
5mg
C651534-5mg
8-12 wks(?) Production requires sourcing of materials. We appreciate your patience and understanding.
$120.90
10mg
C651534-10mg
8-12 wks(?) Production requires sourcing of materials. We appreciate your patience and understanding.
$200.90
25mg
C651534-25mg
8-12 wks(?) Production requires sourcing of materials. We appreciate your patience and understanding.
$420.90
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SDS
Safety data
COA
Certificate
DS
Datasheet
SP
Spec sheet
Overview Specifications Names and Identifiers Documentation Advanced Data Taxonomic Classification 3D Structure Associated Targets(Human) Associated Targets(non-human) Mechanisms of Action Certificates（CoA,COO,BSE/TSE and Analysis Chart) Chemical and Physical Properties Solution Calculators Reviews
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Why this grade

≥99% for sensitive chromatographic and analytical workflows requiring minimal baseline interference.

🌡

Storage & shipping

Store at 2-8°C,Protected from light,Desiccated Ships Wet ice Check lot-specific COA for exact specifications.

📋

Quality documents

SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.

📚

Literature proof

Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.

Overview

Coptisine Sulfate is an alkaloid from Chinese goldthread, and acts as an efficient uncompetitive IDO inhibitor with a K i value of 5.8 μM and an IC 50 value of 6.3 μM

Form:Solid

IC50& Target:IC50: 6.3 μM (IDO), Ki: 5.8 μM (IDO)

Specifications

Synonyms
6, 7-Dihydro[1, 3]dioxolo[4, 5-G][1, 3]dioxolo[7, 8]isoquino[3, 2-A]isoquinolin-5-Ium | 3-Hydroxy-3-methylbutene | 1198398-71-8 | Bis(1, 3)benzodioxolo(5, 6-a:4', 5'-g)quinolizinium, 6, 7-dihydro- | Q5169053 | DTXCID00110895 | 6, 7-Dihydrobis[1, 3]benzodioxolo[5, 6-a:
Specifications & Purity
≥99%
Biochemical and Physiological Mechanisms
Coptisine Sulfate is an alkaloid from Chinese goldthread, and acts as an efficient uncompetitive IDO inhibitor with a K i value of 5.8 μM and an IC 50 value of 6.3 μM.
Storage
Store at 2-8°C, Protected from light, Desiccated
Shipped In
Wet ice
This product requires cold chain shipping. Ground and other economy services are not available.
Action Type
INHIBITOR
Purity
≥99%
Names and Identifiers
Canonical SmilesC1C[N+]2=C(C=C3C=CC4=C(C3=C2)OCO4)C5=CC6=C(C=C51)OCO6
IUPAC Name5,7,17,19-tetraoxa-13-azoniahexacyclo[11.11.0.02,10.04,8.015,23.016,20]tetracosa-1(13),2,4(8),9,14,16(20),21,23-octaene
InChIKeyXYHOBCMEDLZUMP-UHFFFAOYSA-N
INCHI1S/C19H14NO4/c1-2-16-19(24-10-21-16)14-8-20-4-3-12-6-17-18(23-9-22-17)7-13(12)15(20)5-11(1)14/h1-2,5-8H,3-4,9-10H2/q+1
Isomeric SMILES C1C[N+]2=C(C=C3C=CC4=C(C3=C2)OCO4)C5=CC6=C(C=C51)OCO6
PubChem CID 72322
Molecular Weight 320.3

Documentation

📋 Safety Data Sheet (SDS)

Comprehensive hazard, handling, storage, and regulatory compliance document.

Download SDS →

✅ Certificate of Analysis (COA)

Lot-specific quality data. Enter your lot number to retrieve the exact COA.

Look up COA →

📊 Datasheet

Quick-reference summary of product specifications and applications.

View datasheet →

🔬 Specification Sheet

Full quality attributes and acceptance criteria for this grade.

View spec sheet →

Advanced Data

Taxonomic Classification

Taxonomy Tree

KingdomOrganic compounds
SuperclassAlkaloids and derivatives
ClassProtoberberine alkaloids and derivatives
SubclassNot available
Intermediate Tree Nodes Not available
Direct ParentProtoberberine alkaloids and derivatives
Alternative Parents Isoquinolines and derivatives  Benzodioxoles  Pyridinium derivatives  Benzenoids  Heteroaromatic compounds  Oxacyclic compounds  Azacyclic compounds  Acetals  Organopnictogen compounds  Organonitrogen compounds  Hydrocarbon derivatives  Organic cations  
Molecular FrameworkAromatic heteropolycyclic compounds
Substituents Protoberberine skeleton - Isoquinoline - Benzodioxole - Benzenoid - Pyridine - Pyridinium - Heteroaromatic compound - Acetal - Oxacycle - Azacycle - Organoheterocyclic compound - Organic nitrogen compound - Organic oxygen compound - Hydrocarbon derivative - Organooxygen compound - Organonitrogen compound - Organopnictogen compound - Organic cation - Aromatic heteropolycyclic compound
DescriptionThis compound belongs to the class of organic compounds known as protoberberine alkaloids and derivatives. These are alkaloids with a structure based on a protoberberine moiety, which consists of a 5,6-dihydrodibenzene moiety fused to a quinolizinium and forming 5,6-Dihydrodibenzo(a,g)quinolizinium skeleton.
External Descriptors alkaloid
3D Structure
Interactive Chemical Structure Model





Associated Targets(Human)
Panel NCI-60 (60 carcinoma cell lines) (1088 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
HaCaT (4069 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Associated Targets(non-human)
NA Neuraminidase (1107 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Calf thymus DNA (4845 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Mechanisms of Action
Certificates（CoA,COO,BSE/TSE and Analysis Chart)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:
Chemical and Physical Properties
SolubilityDMSO : 1 mg/mL (2.40 mM; ultrasonic and warming and heat to 60°C)
Molecular Weight320.300 g/mol
XLogP33.500
Hydrogen Bond Donor Count0
Hydrogen Bond Acceptor Count4
Rotatable Bond Count0
Exact Mass320.092 Da
Monoisotopic Mass320.092 Da
Topological Polar Surface Area40.800 Ų
Heavy Atom Count24
Formal Charge1
Complexity502.000
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
The total count of all stereochemical bonds0
Covalently-Bonded Unit Count1
Solution Calculators
Reviews

Customer Reviews

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