(D-His(Bzl)6)-LHRH (1-7) free acid , CAS No.1926163-27-0

CAS: 1926163-27-0 Cat. No.: D1431302 PubChem CID: 131698109

Storage

Store at -20°C

Shipped In

Ice chest + Ice pads

Overview

(D-His(Bzl)6)-LHRH (1-7) free acid is a synthetic peptide compound that is a derivative of luteinizing hormone-releasing hormone (LHRH). (D-His(Bzl)6)-LHRH (1-7) free acid enhances its stability and biological activity by introducing unnatural amino acid residues at specific positions of the LHRH molecule. This modification can improve the drug's performance in the body half-life, reducing the rate at which it is rapidly metabolized and cleared, thereby enhancing its efficacy in inhibiting cell proliferation.

Specifications

Storage

Store at -20°C

Shipped In

Ice chest + Ice pads

This product requires cold chain shipping. Ground and other economy services are not available.

Names and Identifiers

• Canonical Smiles: CC(C)CC(C(=O)O)NC(=O)C(CC1=CN(C=N1)CC2=CC=CC=C2)NC(=O)C(CC3=CC=C(C=C3)O)NC(=O)C(CO)NC(=O)C(CC4=CNC5=CC=CC=C54)NC(=O)C(CC6=CN=CN6)NC(=O)C7CCC(=O)N7
• IUPAC Name: (2S)-2-[[(2R)-3-(1-benzylimidazol-4-yl)-2-[[(2S)-2-[[(2S)-3-hydroxy-2-[[(2S)-2-[[(2S)-3-(1H-imidazol-5-yl)-2-[[(2S)-5-oxopyrrolidine-2-carbonyl]amino]propanoyl]amino]-3-(1H-indol-3-yl)propanoyl]amino]propanoyl]amino]-3-(4-hydroxyphenyl)propanoyl]amino]propanoyl]amino]-4-methylpentanoic acid
• InChIKey: PQXRKSVPVKKLGS-NBJPEPGNSA-N
• INCHI: 1S/C53H62N12O11/c1-30(2)18-44(53(75)76)63-51(73)43(22-35-26-65(29-57-35)25-32-8-4-3-5-9-32)62-48(70)40(19-31-12-14-36(67)15-13-31)59-52(74)45(27-66)64-49(71)41(20-33-23-55-38-11-7-6-10-37(33)38)60-50(72)42(21-34-24-54-28-56-34)61-47(69)39-16-17-46(68)58-39/h3-15,23-24,26,28-30,39-45,55,66-67H,16-22,25,27H2,1-2H3,(H,54,56)(H,58,68)(H,59,74)(H,60,72)(H,61,69)(H,62,70)(H,63,73)(H,64,71)(H,75,76)/t39-,40-,41-,42-,43+,44-,45-/m0/s1
• PubChem CID: 131698109