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What types of targets are there? posted this at Jun 9, 2025 Updated at Nov 17, 2024
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What types of targets are there?
target_type
target_desc
parent type
ADMET
Target is not applicable for an ADMET assay (e.g., physchem property)
UNDEFINED
CELL-LINE
Target is a specific cell-line
NON-MOLECULAR
CHIMERIC PROTEIN
Target is a fusion of two different proteins, either a synthetic construct or naturally occurring fusion protein
PROTEIN
LIPID
Target is a lipid
MOLECULAR
MACROMOLECULE
Target is a biological macromolecule (e.g., glycoproteins, hemozoin, hydroxyapatite)
MOLECULAR
METAL
Target is a metal e.g., iron
MOLECULAR
MOLECULAR
Target has been identified as a defined molecular entity (e.g., protein or nucleic acid)
NO TARGET
Target is not applicable for a screening assay (e.g., negative control/counterscreen)
UNDEFINED
NON-MOLECULAR
Target has not been defined at a molecular level, only the non-molecular entity which is affected (e.g., organism, cell line etc)
NUCLEIC-ACID
Target is DNA, RNA or PNA
MOLECULAR
OLIGOSACCHARIDE
Target is an oligosaccharide (e.g., heparin, starch)
MOLECULAR
ORGANISM
Target is a complete organism
NON-MOLECULAR
PHENOTYPE
Target is a biological phenotype or process
NON-MOLECULAR
PROTEIN
Target is a protein or group of proteins
MOLECULAR
PROTEIN COMPLEX
Target is a defined protein complex, consisting of multiple subunits
PROTEIN
PROTEIN COMPLEX GROUP
Target is a poorly defined protein complex, where subunit composition is unclear (e.g., GABA-A receptor)
PROTEIN
PROTEIN FAMILY
Target is a group of closely related proteins
PROTEIN
PROTEIN NUCLEIC-ACID COMPLEX
Target is a complex consisting of both protein and nucleic-acid components (e.g., ribosome)
MOLECULAR
PROTEIN-PROTEIN INTERACTION
Target is the disruption of a protein-protein interaction
PROTEIN
SELECTIVITY GROUP
Target is a pair of proteins for which the selectivity has been assessed
PROTEIN
SINGLE PROTEIN
Target is a single protein chain
PROTEIN
SMALL MOLECULE
Target is a small molecule such as an amino acid, sugar or metabolite)
MOLECULAR
SUBCELLULAR
Target is a subcellular fraction
NON-MOLECULAR
TISSUE
Target is a healthy or diseased tissue
NON-MOLECULAR
UNCHECKED
Target has not yet been assigned
UNDEFINED
UNDEFINED
No target has been defined
UNKNOWN
Molecular identity of target is unknown (e.g., pharmacologically defined target)
UNDEFINED
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