Glycine methyl ester hydrochloride - ≥99% , CAS No.5680-79-5

CAS: 5680-79-5 Cat. No.: G105475 Molecular Weight: 125.55 Beilstein Registry Number: 3593644 EC Number: 227-139-1

GRADE & PURITY ≥99%

Synonyms

BCP25966 | COQRGFWWJBEXRC-UHFFFAOYSA-N | AI3-28814 | AKOS008030449 | Amino-Acetic Acid Methyl Ester HCl | Glycine methyl ester hydrochloride, 99% | AS-12769 | glycine methylester mono hydrochloride | glycine methyl ester, hydrochloride | SCHEMBL2147 | F00

Storage

Store at 2-8°C,Argon charged

Shipped In

Wet ice

Overview

Application：
Glycine methyl ester hydrochloride a non-essential amino acid used for human development.

Specifications

Synonyms

BCP25966 | COQRGFWWJBEXRC-UHFFFAOYSA-N | AI3-28814 | AKOS008030449 | Amino-Acetic Acid Methyl Ester HCl | Glycine methyl ester hydrochloride, 99% | AS-12769 | glycine methylester mono hydrochloride | glycine methyl ester, hydrochloride | SCHEMBL2147 | F00

Specifications & Purity

≥99%

Storage

Store at 2-8°C, Argon charged

Shipped In

Wet ice

This product requires cold chain shipping. Ground and other economy services are not available.

Purity

≥99%

Names and Identifiers

• Pubchem Sid: 504756879
• Pubchem Sid Url: https://pubchem.ncbi.nlm.nih.gov/substance/504756879
• Canonical Smiles: COC(=O)CN.Cl
• IUPAC Name: methyl 2-aminoacetate;hydrochloride
• InChIKey: COQRGFWWJBEXRC-UHFFFAOYSA-N
• INCHI: 1S/C3H7NO2.ClH/c1-6-3(5)2-4;/h2,4H2,1H3;1H
• Isomeric SMILES: COC(=O)CN.Cl
• WGK Germany: 3
• Molecular Weight: 125.55
• Beilstein: 3593644
• Reaxy-Rn: 3593644
• Reaxys-RN_link_address: https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=3593644&ln=

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Organic acids and derivatives
    • Class Carboxylic acids and derivatives
      • Subclass Amino acids, peptides, and analogues
        • Level5 Amino acids and derivatives
          • Level6 Alpha amino acids and derivatives
            • Level7 Alpha amino acid esters

• Kingdom: Organic compounds
• Superclass: Organic acids and derivatives
• Class: Carboxylic acids and derivatives
• Subclass: Amino acids, peptides, and analogues
• Intermediate Tree Nodes: Amino acids and derivatives - Alpha amino acids and derivatives
• Direct Parent: Alpha amino acid esters
• Alternative Parents: Methyl esters Monocarboxylic acids and derivatives Organopnictogen compounds Organic oxides Monoalkylamines Hydrochlorides Hydrocarbon derivatives Carbonyl compounds
• Molecular Framework: Aliphatic acyclic compounds
• Substituents: Alpha-amino acid ester - Methyl ester - Carboxylic acid ester - Monocarboxylic acid or derivatives - Organic nitrogen compound - Hydrocarbon derivative - Hydrochloride - Organic oxide - Primary amine - Organooxygen compound - Organonitrogen compound - Organopnictogen compound - Primary aliphatic amine - Organic oxygen compound - Carbonyl group - Amine - Aliphatic acyclic compound
• Description: This compound belongs to the class of organic compounds known as alpha amino acid esters. These are ester derivatives of alpha amino acids.
• External Descriptors: Not available

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

Mechanisms of Action

Chemical and Physical Properties

• Solubility: Soluble in water; Soluble in Alcohol
• Sensitivity: Moisture sensitive
• Melt Point(°C): 174-175°C
• Molecular Weight: 125.550 g/mol
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 2
• Exact Mass: 125.024 Da
• Monoisotopic Mass: 125.024 Da
• Topological Polar Surface Area: 52.300 Ų
• Heavy Atom Count: 7
• Formal Charge: 0
• Complexity: 52.800
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 0
• Undefined Atom Stereocenter Count: 0
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 2

XLogP3

References

1. Ni Yafei, Li Haimin, Li Ming, Liu Xingchong, Wang Hanyu, Lei Yue, Liu Shuqian, Tang Yanling.  (2023)  Decreased uncoordinated Pb2+ defects induced by Lewis base for high-quality PSCs with much improved carrier transportation.  JOURNAL OF MATERIALS SCIENCE-MATERIALS IN ELECTRONICS,  34  (6): (1-11).  [PMID:] [10.1007/s10854-023-10004-w]

2. Ming Zhao, Hongjun Zhou, Li Hao, Huayao Chen, Xinhua Zhou.  (2021)  A high-efficient nano pesticide-fertilizer combination fabricated by amino acid-modified cellulose based carriers.  PEST MANAGEMENT SCIENCE,  78  (2): (506-520).  [PMID:34551196] [10.1002/ps.6655]

3. Luyao Zheng, Zhiyuan Zhao, Ye Yang, Yaming Li, Chengxiao Wang.  (2020)  Novel skin permeation enhancers based on amino acid ester ionic liquid: Design and permeation mechanism.  INTERNATIONAL JOURNAL OF PHARMACEUTICS,      [PMID:31953082] [10.1016/j.ijpharm.2020.119031]

4. Hecheng Zhu, Jiaming Li, Mengyuan Peng, Min Sha, Ding Zhang, Biao Jiang.  (2025)  Effects of double hydrophilic head groups on the thermodynamic parameters, aggregation behavior, and foam characteristics of amino acid-based fluorocarbon surfactants.  CHEMICAL ENGINEERING SCIENCE,      [PMID:] [10.1016/j.ces.2025.122800]

5. Hao Hu, Hecheng Zhu, Jiaming Li, Ding Zhang, Biao Jiang.  (2026)  Effects of the side chain structure of hydrophilic head group on the properties of amino acid-based fluorocarbon surfactants.  CHEMICAL ENGINEERING SCIENCE,      [PMID:] [10.1016/j.ces.2026.123799]