Determine the necessary mass, volume, or concentration for preparing a solution.
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10mM in Water for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
Store at -80°C Ships Dry ice packs + Cold packs Check lot-specific COA for exact specifications.
SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
Cited in 5 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
product description:
H-HoArg-OH, a homologue arginine, is a strong inhibitor of human bone and liver alkaline phosphatase.
| Canonical Smiles | C(CCN=C(N)N)CC(C(=O)O)N |
|---|---|
| IUPAC Name | (2S)-2-amino-6-(diaminomethylideneamino)hexanoic acid |
| InChIKey | QUOGESRFPZDMMT-YFKPBYRVSA-N |
| INCHI | 1S/C7H16N4O2/c8-5(6(12)13)3-1-2-4-11-7(9)10/h5H,1-4,8H2,(H,12,13)(H4,9,10,11)/t5-/m0/s1 |
| Isomeric SMILES | C(CCN=C(N)N)C[C@@H](C(=O)O)N |
| Molecular Weight | 188.23 |
| Reaxy-Rn | 22844427 |
| Reaxys-RN_link_address | https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=22844427&ln= |
Comprehensive hazard, handling, storage, and regulatory compliance document.
Download SDS →Lot-specific quality data. Enter your lot number to retrieve the exact COA.
Look up COA →Full quality attributes and acceptance criteria for this grade.
View spec sheet →Taxonomy Tree
| Kingdom | Organic compounds |
|---|---|
| Superclass | Organic acids and derivatives |
| Class | Carboxylic acids and derivatives |
| Subclass | Amino acids, peptides, and analogues |
| Intermediate Tree Nodes | Amino acids and derivatives - Alpha amino acids and derivatives - Alpha amino acids |
| Direct Parent | L-alpha-amino acids |
| Alternative Parents | Medium-chain fatty acids Amino fatty acids Guanidines Amino acids Monocarboxylic acids and derivatives Carboxylic acids Carboximidamides Organopnictogen compounds Organic oxides Monoalkylamines Imines Hydrocarbon derivatives Carbonyl compounds |
| Molecular Framework | Aliphatic acyclic compounds |
| Substituents | L-alpha-amino acid - Medium-chain fatty acid - Amino fatty acid - Fatty acid - Fatty acyl - Guanidine - Amino acid - Carboximidamide - Monocarboxylic acid or derivatives - Carboxylic acid - Organic oxide - Organopnictogen compound - Organic oxygen compound - Primary amine - Organooxygen compound - Organonitrogen compound - Primary aliphatic amine - Imine - Carbonyl group - Organic nitrogen compound - Amine - Hydrocarbon derivative - Aliphatic acyclic compound |
| Description | This compound belongs to the class of organic compounds known as l-alpha-amino acids. These are alpha amino acids which have the L-configuration of the alpha-carbon atom. |
| External Descriptors | non-proteinogenic L-alpha-amino acid - L-lysine derivative - homoarginine |
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| Molecular Weight | 188.230 g/mol |
|---|---|
| XLogP3 | -3.700 |
| Hydrogen Bond Donor Count | 4 |
| Hydrogen Bond Acceptor Count | 4 |
| Rotatable Bond Count | 6 |
| Exact Mass | 188.127 Da |
| Monoisotopic Mass | 188.127 Da |
| Topological Polar Surface Area | 128.000 Ų |
| Heavy Atom Count | 13 |
| Formal Charge | 0 |
| Complexity | 189.000 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 1 |
| Undefined Atom Stereocenter Count | 0 |
| Defined Bond Stereocenter Count | 0 |
| Undefined Bond Stereocenter Count | 0 |
| The total count of all stereochemical bonds | 0 |
| Covalently-Bonded Unit Count | 1 |
| 1. Li Liu, Yan-Zhen Chen, Shu-Sheng Zhang, Xiu-Ping Chen, Guo-Qiang Lin, Hang Yin, Chen-Guo Feng, Fang Zhang. (2021) Multiplexed Analysis of Endogenous Guanidino Compounds via Isotope-Coded Doubly Charged Labeling: Application to Lung Cancer Tissues as a Case. ANALYTICAL CHEMISTRY, [PMID:34894659] [10.1021/acs.analchem.1c03835] |
| 2. Ruo-Jing Fan, Fang Zhang, Xiu-Ping Chen, Wan-Shu Qi, Qing Guan, Tuan-Qi Sun, Yin-Long Guo. (2017) High-throughput screening and quantitation of guanidino and ureido compounds using liquid chromatography-drift tube ion mobility spectrometry-mass spectrometry. ANALYTICA CHIMICA ACTA, [PMID:28224912] [10.1016/j.aca.2017.01.036] |
| 3. Ruo-Jing Fan, Qing Guan, Fang Zhang, Jia-Peng Leng, Tuan-Qi Sun, Yin-Long Guo. (2016) Benzylic rearrangement stable isotope labeling for quantitation of guanidino and ureido compounds in thyroid tissues by liquid chromatography-electrospray ionization mass spectrometry. ANALYTICA CHIMICA ACTA, [PMID:26826695] [10.1016/j.aca.2015.12.025] |
| 4. Yunpeng Bai, Yuming Zou, Yingjia Zeng, Linhui Hu, Sumei Huang, Kunyong Wu, Qingxia Yi, Jingchun Chen, Guowu Liang, Yingbang Li, Wendong Huang, Chunbo Chen. (2024) Benzylic rearrangement for urinary analysis of guanidino and ureido compounds in cardiac surgery–associated acute kidney injury using high-performance liquid chromatography–tandem mass spectrometry. RAPID COMMUNICATIONS IN MASS SPECTROMETRY, 38 (17): (1-1572). [PMID:38923063] [10.1002/rcm.9853] |
| 5. Jie Du, Chaoqun Li, Li Chai, Fabao Zhao, Lin Lv, Zongcheng Yang, Zhiyuan Zhao, Rong Gong, Liu Yang, Meng Wu, Meng Nie, Jihui Jia, Dongwei Kang, Chengjiang Gao, Wei Zhao, Mutian Jia. (2026) Asparagine sensing by TBK1 controls its phase separation to drive antiviral innate immune responses. MOLECULAR CELL, 86 (4): (722-739). [PMID:41653919] [10.1016/j.molcel.2026.01.010] |