Mitogen-activated protein kinase kinase kinase kinase 1 (MAP4K1)

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  1. Motesanib, Platelet-derived growth factor receptor inhibitor
    CAS: 453562-69-1 EC Number: 113-839-3 Formula: C22H23N5O Molecular Weight: 373.46
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    In Stock Item #: M126795
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    Technical Identifiers
    IUPAC Name
    N-(3,3-dimethyl-1,2-dihydroindol-6-yl)-2-(pyridin-4-ylmethylamino)pyridine-3-carboxamide
    SMILES
    CC1(CNC2=C1C=CC(=C2)NC(=O)C3=C(N=CC=C3)NCC4=CC=NC=C4)C
    InChIKey
    RAHBGWKEPAQNFF-UHFFFAOYSA-N
    InChI
    1S/C22H23N5O/c1-22(2)14-26-19-12-16(5-6-18(19)22)27-21(28)17-4-3-9-24-20(17)25-13-15-7-10-23-11-8-15/h3-12,26H,13-14H2,1-2H3,(H,24,25)(H,27,28)
    Synonyms
    N-(3,3-dimethyl-1,2-dihydroindol-6-yl)-2-(pyridin-4-ylmethylamino)pyridine-3-carboxamide | NSC800801 | NSC-800801 | H...
  2. HPK1-IN-2
    CAS: 2056122-11-1 Formula: C19H20N6OS Molecular Weight: 380.47
    In Stock Item #: H413402
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    IUPAC Name
    4-amino-5-[6-(4-methylpiperazin-1-yl)-1H-benzimidazol-2-yl]-7H-thieno[2,3-b]pyridin-6-one
    SMILES
    CN1CCN(CC1)C2=CC3=C(C=C2)N=C(N3)C4=C(C5=C(NC4=O)SC=C5)N
    InChIKey
    WKFZMTSRRQSGEY-UHFFFAOYSA-N
    InChI
    1S/C19H20N6OS/c1-24-5-7-25(8-6-24)11-2-3-13-14(10-11)22-17(21-13)15-16(20)12-4-9-27-19(12)23-18(15)26/h2-4,9-10H,5-8H2,1H3,(H,21,22)(H3,20,23,26)
    Synonyms
    Thieno[2,​3-​b]​pyridin-​6(7H)​-​one,4-​amino-​5-​[6-​(4-​methyl-​1-​piperazinyl)​-​1H-​benzimidazol-​2-​yl]​-
  3. HPK1-IN-2
    CAS: 2056122-11-1 Formula: C19H20N6OS Molecular Weight: 380.47
    10mM in DMSO
    In Stock Item #: H422497
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    Technical Identifiers
    IUPAC Name
    4-amino-5-[6-(4-methylpiperazin-1-yl)-1H-benzimidazol-2-yl]-7H-thieno[2,3-b]pyridin-6-one
    SMILES
    CN1CCN(CC1)C2=CC3=C(C=C2)N=C(N3)C4=C(C5=C(NC4=O)SC=C5)N
    InChIKey
    WKFZMTSRRQSGEY-UHFFFAOYSA-N
    InChI
    1S/C19H20N6OS/c1-24-5-7-25(8-6-24)11-2-3-13-14(10-11)22-17(21-13)15-16(20)12-4-9-27-19(12)23-18(15)26/h2-4,9-10H,5-8H2,1H3,(H,21,22)(H3,20,23,26)
    Synonyms
    Thieno[2,​3-​b]​pyridin-​6(7H)​-​one,4-​amino-​5-​[6-​(4-​methyl-​1-​piperazinyl)​-​1H-​benzimidazol-​2-​yl]​-
  4. LSP-249
    CAS: 1801253-04-2 Formula: C24H22ClN5O Molecular Weight: 431.92
    In Stock Item #: L413428
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    Technical Identifiers
    IUPAC Name
    N-[(6-amino-2,4-dimethylpyridin-3-yl)methyl]-2-[(3-chloroquinolin-6-yl)methyl]pyridine-4-carboxamide
    SMILES
    CC1=CC(=NC(=C1CNC(=O)C2=CC(=NC=C2)CC3=CC4=CC(=CN=C4C=C3)Cl)C)N
    InChIKey
    BDLURRLRBKLEDL-UHFFFAOYSA-N
    InChI
    1S/C24H22ClN5O/c1-14-7-23(26)30-15(2)21(14)13-29-24(31)17-5-6-27-20(11-17)9-16-3-4-22-18(8-16)10-19(25)12-28-22/h3-8,10-12H,9,13H2,1-2H3,(H2,26,30)(H,show more
  5. Motesanib, Platelet-derived growth factor receptor inhibitor
    CAS: 453562-69-1 EC Number: 113-839-3 Formula: C22H23N5O Molecular Weight: 373.46
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. 10mM in DMSO
    Out of Stock Item #: M424063
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    Pricing & Pack Sizes
    Technical Identifiers
    IUPAC Name
    N-(3,3-dimethyl-1,2-dihydroindol-6-yl)-2-(pyridin-4-ylmethylamino)pyridine-3-carboxamide
    SMILES
    CC1(CNC2=C1C=CC(=C2)NC(=O)C3=C(N=CC=C3)NCC4=CC=NC=C4)C
    InChIKey
    RAHBGWKEPAQNFF-UHFFFAOYSA-N
    InChI
    1S/C22H23N5O/c1-22(2)14-26-19-12-16(5-6-18(19)22)27-21(28)17-4-3-9-24-20(17)25-13-15-7-10-23-11-8-15/h3-12,26H,13-14H2,1-2H3,(H,24,25)(H,27,28)
    Synonyms
    N-(3,3-dimethyl-1,2-dihydroindol-6-yl)-2-(pyridin-4-ylmethylamino)pyridine-3-carboxamide | NSC800801 | NSC-800801 | H...
  6. HPK1-IN-7
    CAS: 2320462-65-3 PubChem CID: 142587219 Formula: C24H22N6O4 Molecular Weight: 458.5
    Out of Stock Item #: H648327
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    Technical Identifiers
    IUPAC Name
    5-[[4-[[(1S)-2-hydroxy-1-phenylethyl]amino]-5-(1,3,4-oxadiazol-2-yl)pyrimidin-2-yl]amino]-3,3-dimethyl-2-benzofuran-1-one
    SMILES
    CC1(C2=C(C=CC(=C2)NC3=NC=C(C(=N3)NC(CO)C4=CC=CC=C4)C5=NN=CO5)C(=O)O1)C
    InChIKey
    RVSSNRBUPQUIEG-LJQANCHMSA-N
    InChI
    1S/C24H22N6O4/c1-24(2)18-10-15(8-9-16(18)22(32)34-24)27-23-25-11-17(21-30-26-13-33-21)20(29-23)28-19(12-31)14-6-4-3-5-7-14/h3-11,13,19,31H,12H2,1-2H3,show more
  7. LSP-249
    CAS: 1801253-04-2 Formula: C24H22ClN5O Molecular Weight: 431.92
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. 10 mM in DMSO
    Out of Stock Item #: L1495785
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    Pricing & Pack Sizes
    Technical Identifiers
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