Antifolate
Browse by type, application, or key specifications such as purity, grade, packaging, and handling requirements.
109 produits
Produits populaires
- Levomefolate calciumSolid ≥95%● En stock — Entrepôt aux États-Unis, expédition vers l'EU* Article #: L302964Voir le produitTarifs et tailles des emballages
Identificateurs techniques
- Nom IUPAC
- calcium;(2S)-2-[[4-[[(6S)-2-amino-5-methyl-4-oxo-3,6,7,8-tetrahydropteridin-6-yl]methylamino]benzoyl]amino]pentanedioate
- SMILES
- CN1C(CNC2=C1C(=O)NC(=N2)N)CNC3=CC=C(C=C3)C(=O)NC(CCC(=O)[O-])C(=O)[O-].[Ca+2]
- InChIKey
- VWBBRFHSPXRJQD-QNTKWALQSA-L
- InChI
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- Synonymes
- CALCIUM L-5-METHYLTETRAHYDROFOLATE [DSC] | Rhenium, wire reel, 0.2m, diameter 0.076mm, annealed, 99.97% | BAY86-7660 ...
- Folinic acid, calcium salt pentahydrateSolid ≥99%● En stock — Entrepôt aux États-Unis, expédition vers l'EU* Article #: F304111Voir le produitTarifs et tailles des emballages
Identificateurs techniques
- Nom IUPAC
- calcium;(2S)-2-[[4-[(2-amino-5-formyl-4-oxo-3,6,7,8-tetrahydropteridin-6-yl)methylamino]benzoyl]amino]pentanedioate;pentahydrate
- SMILES
- C1C(N(C2=C(N1)N=C(NC2=O)N)C=O)CNC3=CC=C(C=C3)C(=O)NC(CCC(=O)[O-])C(=O)[O-].O.O.O.O.O.[Ca+2]
- InChIKey
- NPPBLUASYYNAIG-ZIGBGYJWSA-L
- InChI
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- Synonymes
- CALCII FOLINAS [WHO-IP LATIN] | 5H-Dibenz(b,f)azepine-5-propanamine, 10,11-dihydro-N,N,beta-trimethyl-, (+)-, (Z)-2-b...
- 10-Formyl Folic AcidCAS: 134-05-4 Formule: C20H19N7O7 Poids moléculaire: 469.41● En stock — Entrepôt aux États-Unis, expédition vers l'EU* Article #: F334434Voir le produitTarifs et tailles des emballages
Identificateurs techniques
- Nom IUPAC
- (2S)-2-[[4-[(2-amino-4-oxo-3H-pteridin-6-yl)methyl-formylamino]benzoyl]amino]pentanedioic acid
- SMILES
- C1=CC(=CC=C1C(=O)NC(CCC(=O)O)C(=O)O)N(CC2=CN=C3C(=N2)C(=O)NC(=N3)N)C=O
- InChIKey
- UGWUWNVTCLDEOG-ZDUSSCGKSA-N
- InChI
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- Synonymes
- 10-Formylpteroylglutamic Acid | 10-Formyldihydropteroylglutamate | L-GLUTAMIC ACID, N-(4-(((2-AMINO-3,4-DIHYDRO-4-OXO...
- Pemetrexed, Inhibitor of dihydrofolate reductase;Inhibitor of phosphoribosylglycinamide formyltransferase; phosphoribosylglycinamide synthetase; phosphoribosylaminoimidazole synthetase;Inhibitor of thymidylate synthetaseMoligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%● En stock — Entrepôt aux États-Unis, expédition vers l'EU* Article #: P125303Voir le produitTarifs et tailles des emballages
Identificateurs techniques
- Nom IUPAC
- (2S)-2-[[4-[2-(2-amino-4-oxo-3,7-dihydropyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoyl]amino]pentanedioic acid
- SMILES
- C1=CC(=CC=C1CCC2=CNC3=C2C(=O)NC(=N3)N)C(=O)NC(CCC(=O)O)C(=O)O
- InChIKey
- WBXPDJSOTKVWSJ-ZDUSSCGKSA-N
- InChI
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- Synonymes
- GTPL5443 | N-({4-[2-(2-amino-4-oxo-4,7-dihydro-1H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]phenyl}carbonyl)-L-glutamic acid...
- Pemetrexed, GAR transformylase inhibitorCAS: 150399-23-8 Formule: C20H19N5Na2O6 Poids moléculaire: 471.37● En stock — Entrepôt aux États-Unis, expédition vers l'EU* Article #: P129841Voir le produitTarifs et tailles des emballages
Identificateurs techniques
- Nom IUPAC
- disodium;(2S)-2-[[4-[2-(2-amino-4-oxo-3,7-dihydropyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoyl]amino]pentanedioate
- SMILES
- C1=CC(=CC=C1CCC2=CNC3=C2C(=O)NC(=N3)N)C(=O)NC(CCC(=O)[O-])C(=O)[O-].[Na+].[Na+]
- InChIKey
- NYDXNILOWQXUOF-GXKRWWSZSA-L
- InChI
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- Synonymes
- CAS-150399-23-8 | Pemetrexed Disodium is known as a Thymidylate synthase inhibitor. | PEMETREXED DISODIUM [USP MONOGR...
- TriméthoprimeSolid Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥99%● En stock — Entrepôt aux États-Unis, expédition vers l'EU* Article #: T129928Voir le produitTarifs et tailles des emballages
Identificateurs techniques
- Nom IUPAC
- 5-[(3,4,5-trimethoxyphenyl)methyl]pyrimidine-2,4-diamine
- SMILES
- COC1=CC(=CC(=C1OC)OC)CC2=CN=C(N=C2N)N
- InChIKey
- IEDVJHCEMCRBQM-UHFFFAOYSA-N
- InChI
- 1S/C14H18N4O3/c1-19-10-5-8(6-11(20-2)12(10)21-3)4-9-7-17-14(16)18-13(9)15/h5-7H,4H2,1-3H3,(H4,15,16,17,18)
- Synonymes
- 5-(3,4,5-Trimethoxybenzyl)-2,4-diaminopyrimidine | Resprim | Bactoprim | Espectrin | Purbal | Roubal | Streptoplus | ...
- Pemetrexed disodium hydrateCAS: 357166-30-4 Numéro CE: 604-733-2, 814-356-7 PubChem CID: 135564527 Formule: C20H21N5O6·5/2H2O·2Na Poids moléculaire: 516.42● En stock — Entrepôt aux États-Unis, expédition vers l'EU* Article #: P140269Voir le produitTarifs et tailles des emballages
Identificateurs techniques
- Nom IUPAC
- tetrasodium;(2S)-2-[[4-[2-(2-amino-4-oxo-3,7-dihydropyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoyl]amino]pentanedioate;pentahydrate
- SMILES
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- InChIKey
- ZCTCZKWJFTYNMZ-WKUCUCPSSA-J
- InChI
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- Synonymes
- UNII-F4GSH45R4C | Pemetrexed accord | (S)-2-(4-(2-(2-Amino-4-oxo-4,7-dihydro-1H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl)be...
- Aminopterin Hydrate● En stock — Entrepôt aux États-Unis, expédition vers l'EU* Article #: A107171Voir le produitTarifs et tailles des emballages
Identificateurs techniques
- Nom IUPAC
- (2S)-2-[[4-[(2,4-diaminopteridin-6-yl)methylamino]benzoyl]amino]pentanedioic acid
- SMILES
- Nc1nc(N)c2nc(CNc3ccc(cc3)C(=O)N[C@@H](CCC(O)=O)C(O)=O)cnc2n1
- InChIKey
- TVZGACDUOSZQKY-LBPRGKRZSA-N
- InChI
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- Synonymes
- CAS-54-62-6 | Kyselina N-(p-((2,4-diamino-6-pteridinylmethyl)amino)benzoyl)-L(+)-glutamova | (2S)-2-[[4-[[(2,4-Diamin...
- Pralatrexate, Dihydrofolate reductase inhibitorCAS: 146464-95-1 Formule: C23H23N7O5 Poids moléculaire: 477.47Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%● En stock — Entrepôt aux États-Unis, expédition vers l'EU* Article #: P125726Voir le produitTarifs et tailles des emballages
Identificateurs techniques
- Nom IUPAC
- (2S)-2-[[4-[1-(2,4-diaminopteridin-6-yl)pent-4-yn-2-yl]benzoyl]amino]pentanedioic acid
- SMILES
- C#CCC(CC1=CN=C2C(=N1)C(=NC(=N2)N)N)C3=CC=C(C=C3)C(=O)NC(CCC(=O)O)C(=O)O
- InChIKey
- OGSBUKJUDHAQEA-WMCAAGNKSA-N
- InChI
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- Synonymes
- (2S)-2-({4-[1-(2,4-diaminopteridin-6-yl)pent-4-yn-2-yl]phenyl}formamido)pentanedioic acid | CHEBI:39196 | (2S)-2-((4-...
- 7-Bromo-2,4-diaminoquinazolineCAS: 137553-43-6 Formule: C8H7BrN4 Poids moléculaire: 239.07● En stock — Entrepôt aux États-Unis, expédition vers l'EU* Article #: B181364Voir le produitTarifs et tailles des emballages
Identificateurs techniques
- Nom IUPAC
- 7-bromoquinazoline-2,4-diamine
- SMILES
- C1=CC2=C(C=C1Br)N=C(N=C2N)N
- InChIKey
- YPWBLOIRVSSESG-UHFFFAOYSA-N
- InChI
- 1S/C8H7BrN4/c9-4-1-2-5-6(3-4)12-8(11)13-7(5)10/h1-3H,(H4,10,11,12,13)
- Synonymes
- DHFR-IN-3 | GS-4262 | 2,4-Quinazolinediamine, 7-bromo- | DTXSID20160236 | J-007040 | SY032047 | 7-Bromo-2,4-diaminoqu...
- Folinic acid calcium salt hydrateCAS: 1492-18-8 Formule: C20H21CaN7O7 · xH2O Poids moléculaire: 511.50 (anhydrous basis)Solid ≥98%● En stock — Entrepôt aux États-Unis, expédition vers l'EU* Article #: F107310Voir le produitTarifs et tailles des emballages
Identificateurs techniques
- Nom IUPAC
- calcium;(2S)-2-[[4-[(2-amino-5-formyl-4-oxo-3,6,7,8-tetrahydropteridin-6-yl)methylamino]benzoyl]amino]pentanedioate
- SMILES
- [Ca++].[H]O[H].[H]C(=O)N1C(CNc2ccc(cc2)C(=O)N[C@@H](CCC([O-])=O)C([O-])=O)CNc3nc(N)nc(O)c13
- InChIKey
- KVUAALJSMIVURS-ZEDZUCNESA-L
- InChI
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- Synonymes
- AMPHOTERICIN B (USP-RS) | Calcii folinas | BUDESONIDE COMPONENT OF BREZTRI | Calcifolin | Folinac | Leucovorin calciu...
- Diaveridine● En stock — Entrepôt aux États-Unis, expédition vers l'EU* Article #: D137262Voir le produitTarifs et tailles des emballages
Identificateurs techniques
- Nom IUPAC
- 5-[(3,4-dimethoxyphenyl)methyl]pyrimidine-2,4-diamine
- SMILES
- COC1=C(C=C(C=C1)CC2=CN=C(N=C2N)N)OC
- InChIKey
- LDBTVAXGKYIFHO-UHFFFAOYSA-N
- InChI
- 1S/C13H16N4O2/c1-18-10-4-3-8(6-11(10)19-2)5-9-7-16-13(15)17-12(9)14/h3-4,6-7H,5H2,1-2H3,(H4,14,15,16,17)
- Synonymes
- CCG-213021 | 2, 5-[(3,4-dimethoxyphenyl)methyl]- | Diaveridina | EN300-7440332 | 5-[(3,4-dimethoxyphenyl)methyl]pyrim...
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Foire aux questions
How is the Antifolate listing put together?
It draws on reported Antifolate annotations within Cell Cycle/DNA Damage and lists each compound with its structure, identifiers, and the activity published for it. Always check the underlying assay before comparing potency values across entries.
How do I choose an Antifolate modulator for my assay?
Start from the assay format and readout — biochemical, cell-based, or in vivo — then compare the Antifolate entries on potency, selectivity over related family members, and solubility in your vehicle. Where several chemotypes are available, a reference compound plus a structurally unrelated backup is the usual way to control for off-target effects.
Which specifications matter most for Antifolate compounds?
Purity and identity confirmation come first, then solubility in DMSO or your chosen vehicle, recommended storage temperature, and stability in solution. For Antifolate work in particular, freshly prepared stocks avoid most of the reproducibility problems seen with stored plates. All products are supplied for professional research and development use only, and are not for use in humans, animals, diagnostics, or therapy.
What if the Antifolate compound I need is not listed?
Search by CAS number or SMILES first, since analogs of Antifolate compounds are often catalogued under a related target. Custom synthesis and bulk enquiries go to [email protected]. We supply verified businesses, research institutions, universities, and government agencies.