AVANTAGE
55 produits
Produits
- GSK PERK inhibitor, Inhibitor of eukaryotic translation initiation factor 2 alpha kinase 3;Inhibitor of myosin light chain kinase 2CAS: 1337531-89-1 Formule: C24H19F4N5O Poids moléculaire: 469.43Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%● En stock — Entrepôt aux États-Unis, expédition vers l'EU* Article #: G355474Voir le produitTarifs et tailles des emballages
Identificateurs techniques
- Nom IUPAC
- 1-[5-(4-amino-7-methylpyrrolo[2,3-d]pyrimidin-5-yl)-2,3-dihydroindol-1-yl]-2-[3-fluoro-5-(trifluoromethyl)phenyl]ethanone
- SMILES
- CN1C=C(C2=C(N=CN=C21)N)C3=CC4=C(C=C3)N(CC4)C(=O)CC5=CC(=CC(=C5)F)C(F)(F)F
- InChIKey
- PXVQGBJMIQCDEX-UHFFFAOYSA-N
- InChI
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- Synonymes
- 1-[5-(4-amino-7-methylpyrrolo[2,3-d]pyrimidin-5-yl)-2, 3-dihydroindol-1-yl]-2-[3-fluoro-5-(trifluoromethyl)phenyl]eth...
- GSK2606414CAS: 1337531-36-8 Formule: C24H20F3N5O Poids moléculaire: 451.44Solid Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%● En stock — Entrepôt aux États-Unis, expédition vers l'EU* Article #: G125654Voir le produitTarifs et tailles des emballages
Identificateurs techniques
- Nom IUPAC
- 1-[5-(4-amino-7-methylpyrrolo[2,3-d]pyrimidin-5-yl)-2,3-dihydroindol-1-yl]-2-[3-(trifluoromethyl)phenyl]ethanone
- SMILES
- CN1C=C(C2=C(N=CN=C21)N)C3=CC4=C(C=C3)N(CC4)C(=O)CC5=CC(=CC=C5)C(F)(F)F
- InChIKey
- SIXVRXARNAVBTC-UHFFFAOYSA-N
- InChI
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- Synonymes
- AC-29016 | 1-(5-(4-amino-7-methyl-7H-pyrrolo[2,3-d]pyrimidin-5-yl)indolin-1-yl)-2-(3-(trifluoromethyl)phenyl)ethanone...
- GSK2656157, Inhibitor of eukaryotic translation initiation factor 2 alpha kinase 3CAS: 1337532-29-2 Formule: C23H21FN6O Poids moléculaire: 416.45Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%● En stock — Entrepôt aux États-Unis, expédition vers l'EU* Article #: G276179Voir le produitTarifs et tailles des emballages
Identificateurs techniques
- Nom IUPAC
- 1-[5-(4-amino-7-methylpyrrolo[2,3-d]pyrimidin-5-yl)-4-fluoro-2,3-dihydroindol-1-yl]-2-(6-methylpyridin-2-yl)ethanone
- SMILES
- CC1=NC(=CC=C1)CC(=O)N2CCC3=C2C=CC(=C3F)C4=CN(C5=NC=NC(=C45)N)C
- InChIKey
- PRWSIEBRGXYXAJ-UHFFFAOYSA-N
- InChI
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- Synonymes
- 1-[5-(4-Amino-7-methyl-7H-pyrrolo[2,3-d]pyrimidin-5-yl)-4-fluoro-2,3-dihydro-1H-indol-1-yl]-2-(6-methyl-2-pyridinyl)e...
- ONO 8130, Antagonist of EP 1 receptorCAS: 459841-96-4 Formule: C25H28N2O5S2 Poids moléculaire: 500.63Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%(HPLC)◐ .Sur commande · 8–12 semaines Article #: O287851Voir le produitTarifs et tailles des emballages
Identificateurs techniques
- Nom IUPAC
- 4-[[6-[2-methylpropyl-[(4-methyl-1,3-thiazol-2-yl)sulfonyl]amino]-2,3-dihydro-1H-inden-5-yl]oxymethyl]benzoic acid
- SMILES
- CC1=CSC(=N1)S(=O)(=O)N(CC(C)C)C2=C(C=C3CCCC3=C2)OCC4=CC=C(C=C4)C(=O)O
- InChIKey
- IOXMDBQCUCDLAF-UHFFFAOYSA-N
- InChI
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- Synonymes
- AC-36636 | BDBM190564 | 4-[[6-[2-methylpropyl-[(4-methyl-1,3-thiazol-2-yl)sulfonyl]amino]-2,3-dihydro-1H-inden-5-yl]o...
- VU 0424465, Agonist of mGlu 5 receptor;Allosteric modulator of mGlu 5 receptorMoligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%(HPLC)◐ .Sur commande · 8–12 semaines Article #: V286883Voir le produitTarifs et tailles des emballages
Identificateurs techniques
- Nom IUPAC
- 5-[2-(3-fluorophenyl)ethynyl]-N-[(2R)-3-hydroxy-3-methylbutan-2-yl]pyridine-2-carboxamide
- SMILES
- CC(C(C)(C)O)NC(=O)C1=NC=C(C=C1)C#CC2=CC(=CC=C2)F
- InChIKey
- ZPKZAFDYFVJULO-CYBMUJFWSA-N
- InChI
- 1S/C19H19FN2O2/c1-13(19(2,3)24)22-18(23)17-10-9-15(12-21-17)8-7-14-5-4-6-16(20)11-14/h4-6,9-13,24H,1-3H3,(H,22,23)/t13-/m1/s1
- Synonymes
- 5-[2-(2-(3-Fluorophenyl)ethynyl]-N-[(1R)-2-hydroxy-1,2-dimethylpropyl]-2-pyridinecarboxamide
- AMG PERK 44CAS: 1883548-84-2 Formule: C34H28N4O2•HCl Poids moléculaire: 561.07● En stock — Entrepôt aux États-Unis, expédition vers l'EU* Article #: A286749Voir le produitTarifs et tailles des emballages
Identificateurs techniques
- Nom IUPAC
- 4-[2-amino-4-methyl-3-(2-methylquinolin-6-yl)benzoyl]-1-methyl-2,5-diphenylpyrazol-3-one;hydrochloride
- SMILES
- CC1=C(C(=C(C=C1)C(=O)C2=C(N(N(C2=O)C3=CC=CC=C3)C)C4=CC=CC=C4)N)C5=CC6=C(C=C5)N=C(C=C6)C.Cl
- InChIKey
- RNAKBTDDCHJCMT-UHFFFAOYSA-N
- InChI
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- Synonymes
- 4-[2-Amino-4-methyl-3-(2-methyl-6-quinolinyl)benzoyl]-1,2-dihydro-1-methyl-2,5-diphenyl-3H-pyrazol-3-one hydrochloride
- NSC 295642CAS: 77111-29-6 Formule: C15H14ClCuN3S2 Poids moléculaire: 399.42◐ .Sur commande · 8–12 semaines Article #: N352361Voir le produitTarifs et tailles des emballages
Identificateurs techniques
- Nom IUPAC
- (E)-benzylsulfanyl-[(E)-1-pyridin-2-ylethylidenehydrazinylidene]-sulfidomethane;chlorocopper(1+)
- SMILES
- CC(=NN=C([S-])SCC1=CC=CC=C1)C2=CC=CC=N2.Cl[Cu+]
- InChIKey
- MGXCRQNCPJBYKM-CWQUOYFRSA-L
- InChI
- 1S/C15H15N3S2.ClH.Cu/c1-12(14-9-5-6-10-16-14)17-18-15(19)20-11-13-7-3-2-4-8-13;;/h2-10H,11H2,1H3,(H,18,19);1H;/q;;+2/p-2/b17-12+;;
- Synonymes
- (E)-benzylsulfanyl-[(E)-1-pyridin-2-ylethylidenehydrazinylidene]-sulfidomethane;chlorocopper(1+) | DTXSID20444568 | N...
- ISRIB (trans-isomer)CAS: 1597403-47-8 Formule: C22H24Cl2N2O4 Poids moléculaire: 451.34● En stock — Entrepôt aux États-Unis, expédition vers l'EU* Article #: I275318Voir le produitTarifs et tailles des emballages
Identificateurs techniques
- Nom IUPAC
- 2-(4-chlorophenoxy)-N-[4-[[2-(4-chlorophenoxy)acetyl]amino]cyclohexyl]acetamide
- SMILES
- C1CC(CCC1NC(=O)COC2=CC=C(C=C2)Cl)NC(=O)COC3=CC=C(C=C3)Cl
- InChIKey
- HJGMCDHQPXTGAV-UHFFFAOYSA-N
- InChI
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- Synonymes
- ISRIB | ISRIB trans-isomer | BCP23947 | ISRIB, >=98% (HPLC) | N,N'-(Cyclohexane-1,4-diyl)bis(2-(4-chlorophenoxy)aceta...
- S-(Carboxymethyl)-L-cysteine● En stock — Entrepôt aux États-Unis, expédition vers l'EU* Article #: S161422Voir le produitTarifs et tailles des emballages
Identificateurs techniques
- Nom IUPAC
- (2R)-2-amino-3-(carboxymethylsulfanyl)propanoic acid
- SMILES
- N[C@@H](CSCC(O)=O)C(O)=O
- InChIKey
- GBFLZEXEOZUWRN-VKHMYHEASA-N
- InChI
- 1S/C5H9NO4S/c6-3(5(9)10)1-11-2-4(7)8/h3H,1-2,6H2,(H,7,8)(H,9,10)/t3-/m0/s1
- Synonymes
- Carbocysteine, L Isomer | Chilvax | Mucodyne | (2R)-2-amino-3-(carboxymethylsulfanyl)propanoic acid | (2R)-2-amino-3-...
- WKYMVmCAS: 187986-17-0 Formule: C41H61N9O7S2 Poids moléculaire: 856.11● En stock — Entrepôt aux États-Unis, expédition vers l'EU* Article #: W275202Voir le produitTarifs et tailles des emballages
Identificateurs techniques
- Synonymes
- Leukocyte chemoattractant peptide
- Obestatin human(trifluoroacetate salt)CAS: 1081110-72-6 PubChem CID: 146156385 Formule: C116H176N32O33（free basis） Poids moléculaire: 2546.86（free basis）● En stock — Entrepôt aux États-Unis, expédition vers l'EU* Article #: O287703Voir le produitTarifs et tailles des emballages
Identificateurs techniques
- Nom IUPAC
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- SMILES
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- InChIKey
- IXQOGPZNKNSCJR-UHFFFAOYSA-N
- InChI
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- GSK2656157, Inhibitor of eukaryotic translation initiation factor 2 alpha kinase 3CAS: 1337532-29-2 Formule: C23H21FN6O Poids moléculaire: 416.45Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. 10mM in DMSO● En stock — Entrepôt aux États-Unis, expédition vers l'EU* Article #: G421276Voir le produitTarifs et tailles des emballages
Identificateurs techniques
- Nom IUPAC
- 1-[5-(4-amino-7-methylpyrrolo[2,3-d]pyrimidin-5-yl)-4-fluoro-2,3-dihydroindol-1-yl]-2-(6-methylpyridin-2-yl)ethanone
- SMILES
- CC1=NC(=CC=C1)CC(=O)N2CCC3=C2C=CC(=C3F)C4=CN(C5=NC=NC(=C45)N)C
- InChIKey
- PRWSIEBRGXYXAJ-UHFFFAOYSA-N
- InChI
- show more
- Synonymes
- 1-[5-(4-Amino-7-methyl-7H-pyrrolo[2,3-d]pyrimidin-5-yl)-4-fluoro-2,3-dihydro-1H-indol-1-yl]-2-(6-methyl-2-pyridinyl)e...
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Foire aux questions
How is the PERK listing put together?
It draws on reported PERK annotations within Cell Cycle/DNA Damage and lists each compound with its structure, identifiers, and the activity published for it. Always check the underlying assay before comparing potency values across entries.
How do I choose a PERK modulator for my assay?
Start from the assay format and readout — biochemical, cell-based, or in vivo — then compare the PERK entries on potency, selectivity over related family members, and solubility in your vehicle. Where several chemotypes are available, a reference compound plus a structurally unrelated backup is the usual way to control for off-target effects.
Which specifications matter most for PERK compounds?
Purity and identity confirmation come first, then solubility in DMSO or your chosen vehicle, recommended storage temperature, and stability in solution. For PERK work in particular, freshly prepared stocks avoid most of the reproducibility problems seen with stored plates. All products are supplied for professional research and development use only, and are not for use in humans, animals, diagnostics, or therapy.
What if the PERK compound I need is not listed?
Search by CAS number or SMILES first, since analogs of PERK compounds are often catalogued under a related target. Custom synthesis and bulk enquiries go to [email protected]. We supply verified businesses, research institutions, universities, and government agencies.